Cited by 55Atrial Fibrillation Management and OutcomesCardiac electrophysiology and arrhythmiasCardiac Arrhythmias and Treatments

Usefulness of P-Wave Dispersion in Standard Twelve-Lead Electrocardiography to Predict Transition from Paroxysmal to Persistent Atrial Fibrillation

Koide, Yasushi, Yotsukura, Masayuki, Ando, Harunori, Aoki, Syuiti, Suzuki, Takaomi, Sakata, Konomi, Ootomo, Eiiti, Yoshino, Hideaki·2008·The American Journal of Cardiology

Abstract

A prospective study was conducted to investigate the validity of the hypothesis that P-wave dispersion (Pd) may be a clinically useful predictor of progression from paroxysmal to persistent atrial fibrillation (AF). Two hundred four consecutive patients with a diagnosis of paroxysmal AF were studied. Standard 12-lead electrocardiography and echocardiography were performed on all patients at the time of entry into the study. Pd was measured as the difference between maximum and minimum P-wave duration in any of the 12 leads. Mean follow-up was 66 +/- 8 months. Group I included patients (n = 132) in whom paroxysmal AF did not progress to persistent AF, and group II included those (n = 72) who developed persistent AF. In group II, age, percentage of men, percentage of patients with diabetes mellitus, maximum P-wave duration, Pd, and left atrial dimension were significantly higher than in group I (p <0.05). Multivariate logistic regression analysis using these 6 factors identified age (odds ratio 2.18, 95% confidence interval 1.41 to 3.41, p <0.01) and Pd (odds ratio 1.91, 95% confidence interval 1.51 to 2.44, p <0.01) as independent predictors of a transition to persistent AF. Pd >or=40 ms predicted progression to persistent AF with sensitivity of 71%, specificity of 77%, positive predictive value of 63%, negative predictive value of 83%, and accuracy of 75%. In conclusion, Pd was a clinically useful predictor of progression from paroxysmal to persistent AF.

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Crossref · 10.1016/j.amjcard.2008.04.065

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  • P-wave dispersion in standard twelve-lead ECG is a good predictor of transition from paroxysmal to persistent atrial fibrillation.

    “P-wave dispersion in standard twelve-lead ECG was found to be a good predictor of transition from paroxysmal to persistent atrial fibrillation. 12”

    From The Year of 2008 in Electrocardiology (2010) · cites this paper as [12]

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Authors
Koide, Y., Yotsukura, M., Ando, H., Aoki, S., Suzuki, T., Sakata, K., Ootomo, E., & Yoshino, H.
Affiliations
  • Yokufukai Hospital (JP)
  • Kyorin University (JP)
Corresponding author
Yoshino, Hideaki
Venue
The American Journal of Cardiology
Publisher
Elsevier BV
Published
2008-09
Volume
102
Issue
5
Pages
573-577
ISSN
0002-9149 (ISSN-L)
OpenAlex
W1989396587
Cited by
55
References
22
Citations by year
2026: 1 · 2025: 3 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 4 · 2020: 1 · 2019: 4 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 7 · 2014: 11 · 2013: 4 · 2012: 5
FWCI
1.45
Type
journal article
Language
en
Open access
closed
Locations
  • The American Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords
P-wave dispersion, paroxysmal atrial fibrillation, persistent atrial fibrillation, atrial fibrillation progression, P-wave duration, electrocardiographic predictors, left atrial diameter, age as risk factor, diabetes mellitus
MeSH terms
Adult, Aged, Atrial Fibrillation, Echocardiography, Electrocardiography, Female, Follow-Up Studies, Heart Atria, Humans, Male, Middle Aged, Predictive Value of Tests, Prospective Studies, Regression Analysis, ROC Curve, Severity of Illness Index, Tachycardia, Paroxysmal, Time Factors, Confidence Intervals, Disease Progression

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