The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Usefulness of Immunosuppression for Giant Cell Myocarditis
Open accessAbstract
Giant cell myocarditis (GCM) is a rare and highly lethal disorder. The only multi-center case series with treatment data lacked data on cardiac function and had a retrospective design. We conducted a prospective, multi-center study of immunosuppression including cyclosporine and steroids for acute, microscopically-confirmed GCM. From June 1999 to June 2005, 11 subjects received high dose steroids, cyclosporine, and in 9 cases muromonab-CD3 in a standard protocol. Among these, 7 of 11 were female, the mean age was 60±15 years, and the mean time from symptom onset to presentation was 27±33 days. During one year of treatment, one subject died of respiratory complications at day 178, and 2 subjects received heart transplantations on days 2 and 27 respectively. Serial endomyocardial biopsies revealed that after 4 weeks of treatment the degree of necrosis, cellular inflammation and giant cells decreased (P=.001). One subject, who completed the trial, subsequently died of a fatal GCM recurrence after withdrawal of immunosuppression. Her case demonstrates for the first time that there is a risk of recurrent, sometimes fatal GCM after cessation of immunosuppression. In conclusion, this prospective study of immunosuppression for GCM confirms retrospective case reports that such therapy improves long-term survival. Additionally, withdrawal of immunosuppression can be associated with fatal GCM recurrence.
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Cites
Idiopathic Giant-Cell Myocarditis — Natural History and Treatment
Cooper, L. T., Berry, G. J., & Shabetai, R. (1997) · New England Journal of Medicine · doi:10.1056/nejm199706263362603 · Cited by 757
Self-citationCaforio, A. L. P., Calabrese, F., Angelini, A., Tona, F., Vinci, A., Bottaro, S., Ramondo, A., Carturan, E., Iliceto, S., Thiene, G., et al. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehm076 · Cited by 484
Kodama, M., Matsumoto, Y., Fujiwara, M., Masani, F., Izumi, T., & Shibata, A. (1990) · Clinical Immunology and Immunopathology · doi:10.1016/0090-1229(90)90039-s · Cited by 330
Caforio, A. L. P., Mahon, N. J., Tona, F., & McKenna, W. J. (2002) · European Journal of Heart Failure · doi:10.1016/s1388-9842(02)00010-7 · Cited by 273
Cytotoxic mAb from rheumatic carditis recognizes heart valves and laminin
Galvin, J. E., Hemric, M. E., Ward, K., & Cunningham, M. W. (2000) · Journal of Clinical Investigation · doi:10.1172/jci7132 · Cited by 248
Self-citationKodama, M., Matsumoto, Y., & FUJIWARA, M. T. (1992) · Circulation · doi:10.1161/01.cir.85.5.1918 · Cited by 120
Lt, C., Berry, G. J., Rizeq, M. N., & SCHROEDER, J. S. (1995) · PubMed · Cited by 73
Costanzo-Nordin, M. R., Silver, M. A., OʼConnell, J. B., Scanlon, P. J., & Robinson, J. A. (1987) · European Heart Journal · doi:10.1093/eurheartj/8.suppl_j.271 · Cited by 26
Cardiac Transplantation for Pediatric Giant Cell Myocarditis
Das, B. B., Recto, M. R., Johnsrude, C. L., Klein, L. R., Orman, K. L., Shoemaker, L. R., Mitchell, M. J., & Austin, E. H. (2006) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2005.11.444 · Cited by 25
Fernandez Martinez, J., & Jesús, D. (1967) · PubMed · Cited by 11
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2013 ACCF/AHA Guideline for the Management of Heart Failure
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.05.019 · Cited by 12,536
Caforio, A. L. P., Pankuweit, S., Arbustini, E., Basso, C., Gimeno-Blanes, J., Felix, S. B., Fu, M., Heliö, T., Heymans, S., Jahns, R., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht210 · Cited by 3,479
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31829e8776 · Cited by 2,106
2020 ESC guidelines on sports cardiology and exercise in patients with cardiovascular disease
Pelliccia, A., Sharma, S., Gati, S., Bäck, M., Börjesson, M., Caselli, S., Collet, J.-P., Corrado, D., Drezner, J. A., Halle, M., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehaa605 · Cited by 1,958
Kindermann, I., Barth, C., Mahfoud, F., Ukena, C., Lenski, M., Yilmaz, A., Klingel, K., Kandolf, R., Sechtem, U., Cooper, L. T., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.09.074 · Cited by 919
Self-citation
Metadata
- Authors
- Cooper, L. T., Hare, J. M., Tazelaar, H. D., Edwards, W. D., Starling, R. C., Deng, M. C., Menon, S., Mullen, G. M., Jaski, B., Bailey, K. R., Cunningham, M. W., & Dec, G. W.
- Venue
- The American Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2008-12
- Volume
- 102
- Issue
- 11
- Pages
- 1535-1539
- ISSN
- 0002-9149 (ISSN-L)
- OpenAlex
- W2039855971
- Cited by
- 320
- References
- 10
- FWCI
- 6.38
- Type
- journal article
- Language
- en
- Open access
- green
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- Cooper, L. T., Hare, J. M., Tazelaar, H. D., Edwards, W. D., Starling, R. C., Deng, M. C., Menon, S., Mullen, G. M., Jaski, B., Bailey, K. R., Cunningham, M. W., & Dec, G. W. (2008). Usefulness of Immunosuppression for Giant Cell Myocarditis. The American Journal of Cardiology. https://doi.org/10.1016/j.amjcard.2008.07.041
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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