Prevalence of Syncope in a Population Aged More Than 45 Years
Abstract
Purpose Our current understanding of the prevalence of syncope is based on a few small studies of highly selected populations. We sought to estimate the prevalence and recurrence rate of syncope in the general population aged more than 45 years and to analyze their associations with age and sex. Methods We performed a cross-sectional survey of 1925 randomly selected residents of Olmsted County, Minn, 45 years or older, from January 1998 to August 2000. Results The median age of the 1925 participants was 62 years, and 905 (47.0%) were male. Overall, 364 subjects reported an episode of syncope in their lifetime, giving an estimated prevalence of 19% (95% confidence interval, 17%-21%). The age-specific prevalence rates were 45 to 54 years (20%), 55 to 64 years (20%), 65 to 74 years (15%), and 75 years or more (21%) (P = .86). Females reported a higher prevalence of syncope (22% vs 15%, P Conclusions The prevalence of syncope is estimated at 19% in the general population aged more than 45 years. Females have a higher prevalence, and there is no association of syncope prevalence with age.
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In a cross section of 1,925 randomly selected residents of Olmsted County, Minnesota, with a median age of 62 years (all age >45 years), 364 reported an episode of syncope in their lifetime; the estimated prevalence of syncope was 19%.
“In a cross section of 1,925 randomly selected residents of Olmsted County, Minnesota, with a median age of 62 years (all age >45 years), 364 reported an episode of syncope in their lifetime; the estimated prevalence of syncope was 19%.”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [44]
Females reported a higher prevalence of syncope than males (22% versus 15%, p<0.001).
“Females reported a higher prevalence of syncope (22% versus 15%, p<0.001) (44).”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [44]
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Prevalence and triggers of syncope in medical students
Ganzeboom, K. S., Colman, N., Reitsma, J. B., Shen, W. K., & Wieling, W. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(03)00127-9 · Cited by 366 · see citing works
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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.03.004 · Cited by 484 · see citing works
Self-citation2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.03.003 · Cited by 327 · see citing works
Self-citationShen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.03.002 · Cited by 155 · see citing works
Self-citationEdvardsson, N., Garutti, C., Rieger, G., Linker, N. J., & for the PICTURE Study Investigators (2014) · Clinical Cardiology · doi:10.1002/clc.22300 · Cited by 28 · see citing works
Dan, G.-A., Scherr, D., Jubele, K., Farkowski, M. M., Iliodromitis, K., Conte, G., Jędrzejczyk-Patej, E., Vitali-Serdoz, L., & Potpara, T. S. (2020) · EP Europace · doi:10.1093/europace/euaa085 · Cited by 20 · see citing works
Childhood trauma and lifetime syncope burden among older adults
O'Hare, C., McCrory, C., O'Leary, N., O'Brien, H., & Kenny, R. A. (2017) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2017.03.019 · Cited by 18 · see citing works
- Authors
- Chen, L. Y., Shen, W.-K., Mahoney, D. W., Jacobsen, S. J., & Rodeheffer, R. J.
- Affiliations
- Mayo Clinic (US)
- Corresponding author
- Chen, Lin Y.
- Venue
- The American Journal of Medicine
- Publisher
- Elsevier BV
- Published
- 2006-12
- Volume
- 119
- Issue
- 12
- Pages
- 1088.e1-1088.e7
- ISSN
- 0002-9343 (ISSN-L)
- OpenAlex
- W2070948364
- Cited by
- 111
- References
- 2
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 19 · 2023: 8 · 2022: 2 · 2021: 6 · 2020: 5 · 2019: 3 · 2018: 5 · 2017: 14 · 2016: 3 · 2015: 1 · 2014: 4 · 2013: 6 · 2012: 5
- FWCI
- 4.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- UCLA - Biblioteca de Ciencias de la Salud (submittedVersion)
- Funders
- National Heart, Lung, and Blood Institute (HL 55502, R01HL055502)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR030582, AR30582)
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- syncope, prevalence, older adults, age-specific prevalence, sex differences, recurrence rate, general population, Olmsted County, Minnesota
- MeSH terms
- Aged, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Syncope, Prevalence
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