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Mobile Health Technology for Atrial Fibrillation Management Integrating Decision Support, Education, and Patient Involvement: mAF App Trial

Open access
Guo, Yutao, Chen, Yundai, Lane, Deirdre A., Liu, Lihong, Wang, Yutang, Lip, Gregory Y.H.·2017·The American Journal of Medicine

Abstract

Background Mobile Health technology for the management of patients with atrial fibrillation is unknown. Methods The simple mobile AF (mAF) App was designed to incorporate clinical decision-support tools (CHA 2 DS 2 -VASc [Congestive heart failure, Hypertension, Age ≥75 years, Diabetes Mellitus, Prior Stroke or TIA, Vascular disease, Age 65–74 years, Sex category], HAS-BLED [Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly, Drugs/alcohol concomitantly], SAMe-TT 2 R 2 [Sex, Age <60 years, Medical history, Treatment, Tobacco use, Race] scores), educational materials, and patient involvement strategies with self-care protocols and structured follow-up. Patients with atrial fibrillation were randomized into 2 groups (mAF App vs usual care) in a cluster randomized design pilot study. Patients' knowledge, quality of life, drug adherence, and anticoagulation satisfaction were evaluated at baseline, 1 month, and 3 months. Usability, feasibility, and acceptability of the mAF App were assessed at 1 month. Results A total of 113 patients were randomized to mAF App intervention (mean age, 67.4 years; 57.5% were male; mean follow-up, 69 days), and 96 patients were randomized to usual care (mean age, 70.9 years; 55.2% were male; mean follow-up, 95 days). More than 90% of patients reported that the mAF App was easy, user-friendly, helpful, and associated with significant improvements in knowledge compared with the usual care arm ( P values for trend <.05). Drug adherence and anticoagulant satisfaction were significantly better with the mAF App versus usual care (all P < .05). Quality of life scores were significantly increased in the mAF App arm versus usual care, with anxiety and depression reduced (all P < .05). Conclusions The pilot mAFA Trial is the first prospective randomized trial of Mobile Health technology in patients with atrial fibrillation, demonstrating that the mAF App, integrating clinical decision support, education, and patient-involvement strategies, significantly improved knowledge, drug adherence, quality of life, and anticoagulation satisfaction.

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Metadata

Authors
Guo, Y., Chen, Y., Lane, D. A., Liu, L., Wang, Y., & Lip, G. Y. H.
Venue
The American Journal of Medicine
Publisher
Elsevier BV
Published
2017-12
Volume
130
Issue
12
Pages
1388-1396.e6
ISSN
0002-9343 (ISSN-L)
OpenAlex
W2745811192
Cited by
230
References
8
FWCI
32.66
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Mobile Health Technology for Atrial Fibrillation Management Integrating Decision Support, Education, and Patient Involvement: mAF App Trial. https://app.cochat.ai/papers/10.1016/j.amjmed.2017.07.003
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Guo, Y., Chen, Y., Lane, D. A., Liu, L., Wang, Y., & Lip, G. Y. H. (2017). Mobile Health Technology for Atrial Fibrillation Management Integrating Decision Support, Education, and Patient Involvement: mAF App Trial. The American Journal of Medicine. https://doi.org/10.1016/j.amjmed.2017.07.003

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