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Cited by 369

The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.

Mobile Health Technology to Improve Care for Patients With Atrial Fibrillation

Open access
Guo, Yutao, Lane, Deirdre A., Wang, Limin, Zhang, Hui, Wang, Hao, Zhang, Wei, Wen, Jing, Xing, Yunli, Wu, Fang, Xia, Yunlong, Liu, Tong, Wu, Fan, Liang, Zhaoguang, Liu, Fan, Zhao, Yujie, Li, Rong, Li, Xin, Zhang, Lili, Guo, Jun, Burnside, Girvan, Chen, Yundai, Lip, Gregory Y.H., Guo, Yutao, Lip, Gregory Y.H., Lane, Deirdre A., Chen, Yundai, Wang, Liming, Eckstein, Jens, Thomas, G Neil, Tong, Liu, Mei, Feng, Xuejun, Liu, Xiaoming, Li, Zhaoliang, Shan, Xiangming, Shi, Wei, Zhang, Yunli, Xing, Jing, Wen, Fan, Wu, Sitong, Yang, Xiaoqing, Jin, Bo, Yang, Xiaojuan, Bai, Yuting, Jiang, Yangxia, Liu, Yingying, Song, Zhongju, Tan, Li, Yang, Tianzhu, Luan, Chunfeng, Niu, Lili, Zhang, Shuyan, Li, Zulu, Wang, Bing, Xv, Liming, Liu, Yuanzhe, Jin, Yunlong, Xia, Xiaohong, Chen, Fang, Wu, Lina, Zhong, Yihong, Sun, Shujie, Jia, Jing, Li, Nan, Li, Shijun, Li, Huixia, Liu, Rong, Li, Fan, Liu, Qingfeng, Ge, Tianyun, Guan, Yuan, Wen, Xin, Li, Yan, Ren, Xiaoping, Chen, Ronghua, Chen, Yun, Shi, Yulan, Zhao, Haili, Shi, Yujie, Zhao, Quanchun, Wang, Weidong, Sun, Lin, Wei, Chan, Esther, Guangliang, Shan, Chen, Yao, Wei, Zong, Dandi, Chen, Xiang, Han, Anding, Xu, Xiaohan, Fan, Ziqiang, Yu, Xiang, Gu, Fulin, Ge·2020·Journal of the American College of Cardiology
DOI 10.1016/j.jacc.2020.01.052
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Abstract

BACKGROUND Current management of patients with atrial fibrillation (AF) is limited by low detection of AF, non-adherence to guidelines, and lack of consideration of patients' preferences, thus highlighting the need for a more holistic and integrated approach to AF management. OBJECTIVE The objective of this study was to determine whether a mobile health (mHealth) technology-supported AF integrated management strategy would reduce AF-related adverse events, compared with usual care. METHODS This is a cluster randomized trial of patients with AF older than 18 years of age who were enrolled in 40 cities in China. Recruitment began on June 1, 2018 and follow-up ended on August 16, 2019. Patients with AF were randomized to receive usual care, or integrated care based on a mobile AF Application (mAFA) incorporating the ABC (Atrial Fibrillation Better Care) Pathway: A, Avoid stroke; B, Better symptom management; and C, Cardiovascular and other comorbidity risk reduction. The primary composite outcome was a composite of stroke/thromboembolism, all-cause death, and rehospitalization. Rehospitalization alone was a secondary outcome. Cardiovascular events were assessed using Cox proportional hazard modeling after adjusting for baseline risk. RESULTS There were 1,646 patients allocated to mAFA intervention (mean age, 67.0 years; 38.0% female) with mean follow-up of 262 days, whereas 1,678 patients were allocated to usual care (mean age, 70.0 years; 38.0% female) with mean follow-up of 291 days. Rates of the composite outcome of 'ischemic stroke/systemic thromboembolism, death, and rehospitalization' were lower with the mAFA intervention compared with usual care (1.9% vs. 6.0%; hazard ratio [HR]: 0.39; 95% confidence interval [CI]: 0.22 to 0.67; p < 0.001). Rates of rehospitalization were lower with the mAFA intervention (1.2% vs. 4.5%; HR: 0.32; 95% CI: 0.17 to 0.60; p < 0.001). Subgroup analyses by sex, age, AF type, risk score, and comorbidities demonstrated consistently lower HRs for the composite outcome for patients receiving the mAFA intervention compared with usual care (all p < 0.05). CONCLUSIONS An integrated care approach to holistic AF care, supported by mHealth technology, reduces the risks of rehospitalization and clinical adverse events. (Mobile Health [mHealth] technology integrating atrial fibrillation screening and ABC management approach trial; ChiCTR-OOC-17014138).

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Authors
Guo, Y., Lane, D. A., Wang, L., Zhang, H., Wang, H., Zhang, W., Wen, J., Xing, Y., Wu, F., Xia, Y., Liu, T., Wu, F., Liang, Z., Liu, F., Zhao, Y., Li, R., Li, X., Zhang, L., Guo, J., Burnside, G., Chen, Y., Lip, G. Y. H., Guo, Y., Lip, G. Y. H., Lane, D. A., Chen, Y., Wang, L., Eckstein, J., Thomas, G. N., Tong, L., Mei, F., Xuejun, L., Xiaoming, L., Zhaoliang, S., Xiangming, S., Wei, Z., Yunli, X., Jing, W., Fan, W., Sitong, Y., Xiaoqing, J., Bo, Y., Xiaojuan, B., Yuting, J., Yangxia, L., Yingying, S., Zhongju, T., Li, Y., Tianzhu, L., Chunfeng, N., Lili, Z., Shuyan, L., Zulu, W., Bing, X., Liming, L., Yuanzhe, J., Yunlong, X., Xiaohong, C., Fang, W., Lina, Z., Yihong, S., Shujie, J., Jing, L., Nan, L., Shijun, L., Huixia, L., Rong, L., Fan, L., Qingfeng, G., Tianyun, G., Yuan, W., Xin, L., Yan, R., Xiaoping, C., Ronghua, C., Yun, S., Yulan, Z., Haili, S., Yujie, Z., Quanchun, W., Weidong, S., Lin, W., Chan, E., Guangliang, S., Chen, Y., Wei, Z., Dandi, C., Xiang, H., Anding, X., Xiaohan, F., Ziqiang, Y., Xiang, G., & Fulin, G.
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2020-04
Volume
75
Issue
13
Pages
1523-1534
ISSN
0735-1097 (ISSN-L)
DOI
10.1016/j.jacc.2020.01.052
OpenAlex
W3013924214
Cited by
369
References
29
FWCI
30.59
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Mobile Health Technology to Improve Care for Patients With Atrial Fibrillation. https://app.cochat.ai/papers/10.1016/j.jacc.2020.01.052
The paper
Guo, Y., Lane, D. A., Wang, L., Zhang, H., Wang, H., Zhang, W., Wen, J., Xing, Y., Wu, F., Xia, Y., Liu, T., Wu, F., Liang, Z., Liu, F., Zhao, Y., Li, R., Li, X., Zhang, L., Guo, J., . . . Fulin, G. (2020). Mobile Health Technology to Improve Care for Patients With Atrial Fibrillation. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2020.01.052

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