The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Diagnosis and Treatment of Peptic Ulcer Disease
Abstract
Peptic ulcer disease continues to be a source of significant morbidity and mortality worldwide. Approximately two-thirds of patients found to have peptic ulcer disease are asymptomatic. In symptomatic patients, the most common presenting symptom of peptic ulcer disease is epigastric pain, which may be associated with dyspepsia, bloating, abdominal fullness, nausea, or early satiety. Most cases of peptic ulcer disease are associated with Helicobacter pylori infection or the use of nonsteroidal anti-inflammatory drugs (NSAIDs), or both. In this review, we discuss the role of proton pump inhibitors in the management of peptic ulcer disease, highlight the latest guidelines about the diagnosis and management of H. pylori, and discuss the latest evidence in the management of complications related to peptic ulcer disease, including endoscopic intervention for peptic ulcer-related bleeding. Timely diagnosis and treatment of peptic ulcer disease and its sequelae are crucial in order to minimize associated morbidity and mortality, as is prevention of peptic ulcer disease among patients at high risk, including those infected with H. pylori and users of NSAIDs.
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Cites
Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration
Marshall, B., & Warren, J. R. (1984) · The Lancet · doi:10.1016/s0140-6736(84)91816-6 · Cited by 5,509
UNIDENTIFIED CURVED BACILLI ON GASTRIC EPITHELIUM IN ACTIVE CHRONIC GASTRITIS
ROBINWARREN, J. (1983) · The Lancet · doi:10.1016/s0140-6736(83)92719-8 · Cited by 3,597
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
Malfertheiner, P., Megraud, F., O'Morain, C. A., Gisbert, J. P., Kuipers, E. J., Axon, A. T., Bazzoli, F., Gasbarrini, A., Atherton, J., Graham, D. Y., et al. (2017) · Gut · doi:10.1136/gutjnl-2016-312288 · Cited by 2,946
Pathogenesis of Helicobacter pylori Infection
Kusters, J. G., van Vliet, A. H. M., & Kuipers, E. J. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.00054-05 · Cited by 2,526
ACG Clinical Guideline: Treatment of Helicobacter pylori Infection
Chey, W. D., Leontiadis, G. I., Howden, C. W., & Moss, S. F. (2017) · American Journal of Gastroenterology · doi:10.1038/ajg.2016.563 · Cited by 1,604
Malfertheiner, P., Chan, F. K., & McColl, K. E. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60938-7 · Cited by 1,488
Helicobacter pylori in peptic ulcer disease.
van Rensburg, O. (2004) · PubMed · Cited by 1,310
Freedberg, D. E., Kim, L. S., & Yang, Y.-X. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.01.031 · Cited by 891
Gralnek, I., Dumonceau, J.-M., Kuipers, E., Lanas, A., Sanders, D., Kurien, M., Rotondano, G., Hucl, T., Dinis-Ribeiro, M., Marmo, R., et al. (2015) · Endoscopy · doi:10.1055/s-0034-1393172 · Cited by 828
Self-citationManagement of Patients With Ulcer Bleeding
Laine, L., & Jensen, D. M. (2012) · American Journal of Gastroenterology · doi:10.1038/ajg.2011.480 · Cited by 807
Cited by
Perforated and bleeding peptic ulcer: WSES guidelines
Tarasconi, A., Coccolini, F., Biffl, W. L., Tomasoni, M., Ansaloni, L., Picetti, E., Molfino, S., Shelat, V., Cimbanassi, S., Weber, D. G., et al. (2020) · World Journal of Emergency Surgery · doi:10.1186/s13017-019-0283-9 · Cited by 373
Metadata
- Authors
- Kavitt, R. T., Lipowska, A. M., Anyane-Yeboa, A., & Gralnek, I. M.
- Venue
- The American Journal of Medicine
- Publisher
- Elsevier BV
- Published
- 2019-04
- Volume
- 132
- Issue
- 4
- Pages
- 447-456
- ISSN
- 0002-9343 (ISSN-L)
- OpenAlex
- W2908381102
- Cited by
- 313
- References
- 46
- FWCI
- 25.28
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kavitt, R. T., Lipowska, A. M., Anyane-Yeboa, A., & Gralnek, I. M. (2019). Diagnosis and Treatment of Peptic Ulcer Disease. The American Journal of Medicine. https://doi.org/10.1016/j.amjmed.2018.12.009
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
