Post COVID-19 splenic infarction with limb ischemia: A case report
Open accessAbstract
INTRODUCTION: and importance: COVID-19 has been associated with thrombotic events in a variety of organs and systems, with pulmonary embolism being the most prevalent. Splenic infarction, renal infarction, and intestinal ischemia have all been documented recently as abdominal visceral infarctions. CASE PRESENTATION: A 59 years old female patient with a history of COVID-19 disease was admitted to our hospital due to her left upper quadrant abdominal and left flank pain. She had a history of left heel color change in few days. We perform an ultrasound and it was shown vein thrombosis. So, heparin infusion was started for her. We also performed a thoraco-abdominopelvic computed tomography (CT) with intravenous and oral contrast. Total evidence suggests a splenic system infarction. A regular clinical examination for malignancy was performed on the patient and there was no evidence of cancer. Other probable reasons were ruled out. The patient was diagnosed with splenic infarction, Due to coagulopathy caused by SARS-Cov-2 infection. Treatment with heparin was continued for 5 days and she was discharged home on day 9 with oral agents. The patient was asymptomatic when she returned. The spleen had decreased in size on the follow-up CT, and there were no clinical complications. DISCUSSION AND CONCLUSIONS: Spleen artery thrombosis is a rare complication of COVID-19. In this report, we described a 59 years old female with a history of COVID-19. She was discharged home and in follow-up, there was no evidence of thrombosis anymore.
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COVID-19 is known to cause significant alteration of coagulation, causing thromboembolic acute events, of which the most documented were pulmonary embolism, acute myocardial infarction, and lower limb ischemia.
“COVID-19 is known to cause significant alteration of coagulation, causing thromboembolic acute events, of which the most documented were pulmonary embolism, acute myocardial infarction, and lower limb ischemia [6].”
From Acute mesenteric ischemia in COVID-19 patients (2021) · cites this paper as [6]
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Amr, Y. S., Al-Omari, A. Q., Saadeh, M. H., & Amr, S. S. (2025) · Open Journal of Pathology · doi:10.4236/ojpathology.2025.152007
- Authors
- Moradi, H., Mouzannar, S., & Miratashi Yazdi, S. A.
- Affiliations
- Isfahan University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
- Venue
- Annals of Medicine and Surgery
- Published
- 2021-11
- Volume
- 71
- Pages
- 102935
- ISSN
- 2049-0801 (ISSN-L)
- PMC
- PMC8500846
- OpenAlex
- W3205082871
- Cited by
- 6
- References
- 17
- Citations by year
- 2025: 1 · 2023: 1 · 2022: 3 · 2021: 1
- FWCI
- 0.40
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Annals of Medicine and Surgery (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic Thrombus and Embolism
- Keywords
- COVID-19 pandemic, splenic infarction, splenic artery thrombosis, limb ischemia, venous thrombosis, heparin anticoagulation, coagulopathy, SARS-CoV-2
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