CoChat
Sign Up
Cited by 17

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

8-Iso-prostaglandin F2α as a biomarker of type 2 low airway inflammation and remodeling in adult asthma

Woo, Seong-Dae, Park, Hee Sun, Yang, Eun-Mi, Ban, Ga-Young, Park, Hae-Sim·2024·Annals of Allergy, Asthma & Immunology
DOI 10.1016/j.anai.2024.04.007
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.anai.2024.04.007

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Figures

Figure 1 (A) Comparisons of urinary 8-iso-PGF2 a concentrations among noneosinophilic and eosinophilic asthma groups and healthy control participants. (B) Receiver operating characteristic curve analysis for distinguishing noneosinophilic asthma in patients with asthma. AUC, area under the curve; PGF2 a , prostaglandin F2 a .
Figure 1 (A) Comparisons of urinary 8-iso-PGF2 a concentrations among noneosinophilic and eosinophilic asthma groups and healthy control participants. (B) Receiver operating characteristic curve analysis for distinguishing noneosinophilic asthma in patients with asthma. AUC, area under the curve; PGF2 a , prostaglandin F2 a .CC-BY-NC-ND · From the PDF
Figure 2 Spearman correlations of urinary 8-iso-PGF2 a concentrations with serum markers associated with neutrophilic in fl ammation (A, B), epithelial-derived airway remodeling (C-E), and antioxidant property (F) in patients with asthma. 8-iso-PGF2 a , 8-iso-prostaglandin F2 a ; CC16, club cell protein 16; MMP-9, matrix metalloproteinase; MPO, myeloperoxidase; TGFb 1, transforming growth factor b 1; TIMP-1, tissue inhibitor of metalloproteinase-1.
Figure 2 Spearman correlations of urinary 8-iso-PGF2 a concentrations with serum markers associated with neutrophilic in fl ammation (A, B), epithelial-derived airway remodeling (C-E), and antioxidant property (F) in patients with asthma. 8-iso-PGF2 a , 8-iso-prostaglandin F2 a ; CC16, club cell protein 16; MMP-9, matrix metalloproteinase; MPO, myeloperoxidase; TGFb 1, transforming growth factor b 1; TIMP-1, tissue inhibitor of metalloproteinase-1.CC-BY-NC-ND · From the PDF
Figure 3 Spearman correlations of urinary 8-iso-PGF2 a concentrations with lung function parameters (A-D) and airway reversibility (E) in patients with asthma. 8-iso-PGF2 a , 8iso-prostaglandin F2 a ; FEF25%-75%, forced expiratory fl ow at 25% to 75% of FVC; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity.
Figure 3 Spearman correlations of urinary 8-iso-PGF2 a concentrations with lung function parameters (A-D) and airway reversibility (E) in patients with asthma. 8-iso-PGF2 a , 8iso-prostaglandin F2 a ; FEF25%-75%, forced expiratory fl ow at 25% to 75% of FVC; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity.CC-BY-NC-ND · From the PDF
Figure 4 Comparative analysis of urinary 8-iso-PGF2 a concentrations according to asthma symptom scores in 114 patients with asthma by ACQ-6 (A), ACT (B), and AQLQ (C). 8-isoPGF2 a , 8-iso-prostaglandin F2 a ; ACQ-6, asthma control questionnaire-6; ACT, asthma control test; AQLQ, asthma quality of life questionnaire.
Figure 4 Comparative analysis of urinary 8-iso-PGF2 a concentrations according to asthma symptom scores in 114 patients with asthma by ACQ-6 (A), ACT (B), and AQLQ (C). 8-isoPGF2 a , 8-iso-prostaglandin F2 a ; ACQ-6, asthma control questionnaire-6; ACT, asthma control test; AQLQ, asthma quality of life questionnaire.CC-BY-NC-ND · From the PDF
Figure 5 (A, D) Comparison of urine and serum concentrations between obese and nonobese asthma groups. (B) Comparison of urinary 8-iso-PGF2 a concentrations between smokers and nonsmokers asthma groups. (C) Pearson correlations of urinary 8-iso-PGF2 a concentrations with age in patients with asthma. 8-iso-PGF2 a , 8-iso-prostaglandin F2 a ; BMI, body mass index.
Figure 5 (A, D) Comparison of urine and serum concentrations between obese and nonobese asthma groups. (B) Comparison of urinary 8-iso-PGF2 a concentrations between smokers and nonsmokers asthma groups. (C) Pearson correlations of urinary 8-iso-PGF2 a concentrations with age in patients with asthma. 8-iso-PGF2 a , 8-iso-prostaglandin F2 a ; BMI, body mass index.CC-BY-NC-ND · From the PDF
Image 6
CC-BY-NC-ND · From the PDF
eFigure 2. Serum 8-iso-PGF2 a concentrations in adult asthma. Comparisons of serum 8-iso-PGF2 a concentrations between patients with asthma and healthy control participants (A), and spearman correlations between serum and urinary 8-iso-PGF2 a concentrations (B). 8-iso-PGF2 a , 8-iso-prostaglandin F2 a .
eFigure 2. Serum 8-iso-PGF2 a concentrations in adult asthma. Comparisons of serum 8-iso-PGF2 a concentrations between patients with asthma and healthy control participants (A), and spearman correlations between serum and urinary 8-iso-PGF2 a concentrations (B). 8-iso-PGF2 a , 8-iso-prostaglandin F2 a .CC-BY-NC-ND · From the PDF

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 1 references

Research works printed but not linked: 28

  1. Porsbjerg, 2023, Asthma, Lancet, 401, 858, 10.1016/S0140-6736(22)02125-0 · DOI
  2. Sokolowska, 2021, Current perspective on eicosanoids in asthma and allergic diseases: EAACI Task Force consensus report, part I, Allergy, 76, 114, 10.1111/all.14295 · DOI
  3. Kolmert, 2021, Urinary leukotriene E4 and prostaglandin D2 metabolites increase in adult and childhood severe asthma characterized by type 2 inflammation. A clinical observational study, Am J Respir Crit Care Med, 203, 37, 10.1164/rccm.201909-1869OC · DOI
  4. Sahiner, 2011, Oxidative stress in asthma, World Allergy Organ J, 4, 151, 10.1097/WOX.0b013e318232389e · DOI
  5. Basu, 2010, Bioactive eicosanoids: role of prostaglandin F 2α and F 2-isoprostanes in inflammation and oxidative stress related pathology, Mol Cells, 30, 383, 10.1007/s10059-010-0157-1 · DOI
  6. Milne, 2011, Isoprostane generation and function, Chem Rev, 111, 5973, 10.1021/cr200160h · DOI
  7. Jonasson, 2009, Allergen-induced formation of F2-isoprostanes in a murine asthma model identifies oxidative stress in acute airway inflammation in vivo, Prostaglandins Leukot Essent Fatty Acids, 80, 1, 10.1016/j.plefa.2008.10.001 · DOI
  8. Wood, 2005, Induced sputum 8-isoprostane concentrations in inflammatory airway diseases, Am J Respir Crit Care Med, 171, 426, 10.1164/rccm.200408-1010OC · DOI
  9. Morrow, 1995, Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers—smoking as a cause of oxidative damage, N Engl J Med, 332, 1198, 10.1056/NEJM199505043321804 · DOI
  10. Abdo, 2021, Raised sputum extracellular DNA confers lung function impairment and poor symptom control in an exacerbation-susceptible phenotype of neutrophilic asthma, Respir Res, 22, 167, 10.1186/s12931-021-01759-z · DOI
  11. Svenningsen, 2017, Asthma endotypes and an overview of targeted therapy for asthma, Front Med., 4, 158, 10.3389/fmed.2017.00158 · DOI
  12. Wan, 2020, Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/NF-κB pathway and secrete chemokines, Aging (Albany NY), 12, 16820, 10.18632/aging.103479 · DOI
  13. Quoc, 2021, S100A9 in adult asthmatic patients: a biomarker for neutrophilic asthma, Exp Mol Med, 53, 1170, 10.1038/s12276-021-00652-5 · DOI
  14. Juniper, 1999, Development and validation of a questionnaire to measure asthma control, Eur Respir J, 14, 902, 10.1034/j.1399-3003.1999.14d29.x · DOI · Paper page
  15. Sá-Sousa, 2015, Asthma control in the Portuguese National Asthma Survey, Rev Port Pneumol (2006), 21, 209
  16. Louis, 2023, Predictors of change in asthma-related quality of life: a longitudinal real-life study in adult asthmatics, Qual Life Res, 32, 1507, 10.1007/s11136-022-03339-0 · DOI
  17. Lee, 2021, Biomarkers for severe asthma: lessons from longitudinal cohort studies, Allergy Asthma Immunol Res, 13, 375, 10.4168/aair.2021.13.3.375 · DOI
  18. Dworski, 2001, Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2α), Clin Exp Allergy, 31, 387, 10.1046/j.1365-2222.2001.01055.x · DOI
  19. Monteseirín, 2001, Elevated secretion of myeloperoxidase by neutrophils from asthmatic patients: the effect of immunotherapy, J Allergy Clin Immunol, 107, 623, 10.1067/mai.2001.113566 · DOI
  20. Dickerhof, 2020, Myeloperoxidase inhibition decreases morbidity and oxidative stress in mice with cystic fibrosis-like lung inflammation, Free Radic Biol Med, 152, 91, 10.1016/j.freeradbiomed.2020.03.001 · DOI
  21. Sousa, 1994, Increased expression of the monocyte chemoattractant protein-1 in bronchial tissue from asthmatic Participants, Am J Respir Cell Mol Biol, 10, 142, 10.1165/ajrcmb.10.2.8110469 · DOI
  22. Barbaro, 2014, Exhaled matrix metalloproteinase-9 (MMP-9) in different biological phenotypes of asthma, Eur J Intern Med, 25, 92, 10.1016/j.ejim.2013.08.705 · DOI
  23. Kim, 2023, Roles of tissue inhibitor of metalloproteinase-1 in severe asthma, Allergy Asthma Immunol Res, 15, 416, 10.4168/aair.2023.15.4.416 · DOI
  24. Halwani, 2011, Role of transforming growth factor–β in airway remodeling in asthma, Am J Respir Cell Mol Biol, 44, 127, 10.1165/rcmb.2010-0027TR · DOI
  25. Goudarzi, 2023, Association of serum CC16 levels with eosinophilic inflammation and respiratory dysfunction in severe asthma, Respir Med, 206, 10.1016/j.rmed.2022.107089 · DOI
  26. Quoc, 2024, Contribution of monocyte and macrophage extracellular traps to neutrophilic airway inflammation in severe asthma, Allergol Int, 73, 81, 10.1016/j.alit.2023.06.004 · DOI
  27. Vazzana, 2013, Enhanced lipid peroxidation and platelet activation as potential contributors to increased cardiovascular risk in the low-HDL phenotype, J Am Heart Assoc, 2, 10.1161/JAHA.113.000063 · DOI
  28. Fitzpatrick, 2020, T2-“low” asthma: overview and management strategies, J Allergy Clin Immunol Pract, 8, 452, 10.1016/j.jaip.2019.11.006 · DOI

Cited by

Sorted by citations

See all 17

Metadata

Authors
Woo, S.-D., Park, H. S., Yang, E.-M., Ban, G.-Y., & Park, H.-S.
ORCID
Park, Hae-Sim
Venue
Annals of Allergy, Asthma & Immunology
Publisher
Elsevier BV
Published
2024-07
Volume
133
Issue
1
Pages
73-80.e2
ISSN
1081-1206
DOI
10.1016/j.anai.2024.04.007
Cited by
17
References
1
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: 8-Iso-prostaglandin F2α as a biomarker of type 2 low airway inflammation and remodeling in adult asthma. https://app.cochat.ai/papers/10.1016/j.anai.2024.04.007
The paper
Woo, S.-D., Park, H. S., Yang, E.-M., Ban, G.-Y., & Park, H.-S. (2024). 8-Iso-prostaglandin F2α as a biomarker of type 2 low airway inflammation and remodeling in adult asthma. Annals of Allergy, Asthma & Immunology. https://doi.org/10.1016/j.anai.2024.04.007