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Cited by 496Antimicrobial Resistance in StaphylococcusDermatological diseases and infestationsOtolaryngology and Infectious Diseases

The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.

High Prevalence of Methicillin-Resistant Staphylococcus aureus in Emergency Department Skin and Soft Tissue Infections

Frazee, Bradley W., Lynn, Jeremy, Charlebois, Edwin D., Lambert, Larry, Lowery, Derrick, Perdreau-Remington, Francoise·2005·Annals of Emergency Medicine
DOI 10.1016/j.annemergmed.2004.10.011
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Abstract

Study objective We sought to determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) among emergency department (ED) patients with skin and soft tissue infections, identify demographic and clinical variables associated with MRSA, and characterize MRSA by antimicrobial susceptibility and genotype. Methods This was a prospective observational study involving a convenience sample of patients who presented with skin and soft tissue infections to a single urban public hospital ED in California. Nares and infection site cultures were obtained. A health and lifestyle questionnaire was administered, and predictor variables independently associated with MRSA were determined by multivariate logistic regression. All S aureus isolates underwent antibiotic susceptibility testing. Eighty-five MRSA isolates underwent genotyping by pulsed field gel electrophoresis, staphylococcal chromosomal cassette mec (SCC mec ) typing, and testing for Panton-Valentine leukocidin genes. Results Of 137 subjects, 18% were homeless, 28% injected illicit drugs, 63% presented with a deep or superficial abscess, and 26% required admission for the infection. MRSA was present in 51% of infection site cultures. Of 119 S aureus isolates (from infection site and nares), 89 (75%) were MRSA. Antimicrobial susceptibility among MRSA isolates was trimethoprim/sulfamethoxazole 100%, clindamycin 94%, tetracycline 86%, and levofloxacin 57%. Among predictor variables independently associated with MRSA…

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Metadata

Authors
Frazee, B. W., Lynn, J., Charlebois, E. D., Lambert, L., Lowery, D., & Perdreau-Remington, F.
Affiliations
University of California, San Francisco (US)
Corresponding author
Frazee, Bradley W.
ORCID
Venue
Annals of Emergency Medicine
Publisher
Elsevier BV
Published
2005-03
Volume
45
Issue
3
Pages
311-320
ISSN
0196-0644 (ISSN-L)
DOI
10.1016/j.annemergmed.2004.10.011
OpenAlex
W2148133809
Cited by
494
References
62
Citations by year
2026: 2 · 2025: 11 · 2024: 11 · 2023: 11 · 2022: 10 · 2021: 9 · 2020: 10 · 2019: 15 · 2018: 15 · 2017: 11 · 2016: 13 · 2015: 25 · 2014: 23 · 2013: 24 · 2012: 30
FWCI
21.05
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Annals of Emergency Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
  • Health Sciences › Medicine › Infectious Diseases › Dermatological diseases and infestations
  • Health Sciences › Medicine › Infectious Diseases › Otolaryngology and Infectious Diseases
Keywords
methicillin-resistant Staphylococcus aureus, skin and soft tissue infections, emergency department patients, community-acquired MRSA, antimicrobial susceptibility, Panton-Valentine leukocidin, furunculosis, risk factors, homeless patients, intravenous drug use, empirical antibiotic therapy, abscess
MeSH terms
Adolescent, Adult, California, Carrier State, Emergency Service, Hospital, Female, Furunculosis, Genotype, Humans, Male, Microbial Sensitivity Tests, Middle Aged, Nose, Prospective Studies, Staphylococcal Infections, Staphylococcal Skin Infections, Staphylococcus aureus, Urban Health, Prevalence, Logistic Models, Odds Ratio, Methicillin Resistance, Community-Acquired Infections, Soft Tissue Infections

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