Can forced-use therapy be clinically applied after stroke? an exploratory randomized controlled trial11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.

Ploughman, Michelle; Corbett, Dale

doi:10.1016/j.apmr.2004.01.018

Cited by 106Stroke Rehabilitation and RecoveryTranscranial Magnetic Stimulation StudiesSpatial Neglect and Hemispheric Dysfunction

Can forced-use therapy be clinically applied after stroke? an exploratory randomized controlled trial11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.

Ploughman, Michelle, Corbett, Dale·2004·Archives of Physical Medicine and Rehabilitation

DOI 10.1016/j.apmr.2004.01.018

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Abstract

Objective To determine the efficacy, safety, and compliance with forced-use therapy (FUT) applied without additional "shaping" therapy during the rehabilitation phase of stroke. Design Prospective, randomized controlled trial. Setting Tertiary mixed rehabilitation center. Participants Consecutive sample of 30 inpatients or outpatients with first stroke showing minimal movement of the arm and hand. Subjects who scored below 26 on the Mini-Mental State Examination were excluded. Seven subjects either did not provide consent or withdrew from the study. The remaining subjects were randomized into the control group (n=13) and the FUT group (n=10). Intervention FUT involved wearing a thick constraint mitten on the sound arm for as many as 6 hours a day. Main outcome measures The Chedoke McMaster Impairment Inventory for arm, hand, postural control, and shoulder pain; Action Research Arm Test; grip strength; and FIM instrument. Results FUT subjects experienced 20% more recovery of the arm than did control subjects and more recovery of postural control (P=.04). Men benefited most from the program, and there was a tendency for FUT subjects to have more shoulder pain. Compliance was related to cognitive status. Conclusions FUT, without shaping therapy, appears to augment arm recovery, but a larger sample is required to confirm these findings. The FUT mitten was safe and well tolerated; however, more research is needed to determine the relation between FUT and hemiplegic shoulder pain.

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This relationship is subject to a dose-response increase, i.e., more intense training leads to a better response.
“This relationship is subject to a dose-response increase, ie, more intense training leads to a better response.8”
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Authors: Ploughman, M., & Corbett, D.
Affiliations: Memorial University of Newfoundland (CA)
Corresponding author: Ploughman, Michelle
ORCID: Ploughman, Michelle
Corbett, Dale
Venue: Archives of Physical Medicine and Rehabilitation
Publisher: Elsevier BV
Published: 2004-09
Volume: 85
Issue: 9
Pages: 1417-1423
ISSN: 0003-9993 (ISSN-L)
DOI: 10.1016/j.apmr.2004.01.018
OpenAlex: W1967959307
Cited by: 106
References: 20
Citations by year: 2026: 1 · 2025: 2 · 2024: 1 · 2023: 5 · 2021: 1 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 4 · 2014: 6 · 2013: 11 · 2012: 11
FWCI: 5.76
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Archives of Physical Medicine and Rehabilitation (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
Life Sciences › Neuroscience › Cognitive Neuroscience › Spatial Neglect and Hemispheric Dysfunction
Keywords: stroke rehabilitation, constraint-induced movement therapy, arm recovery, postural control, shoulder pain, hemiplegia, grip strength, medication adherence, cognitive status
MeSH terms: Stroke Rehabilitation, Activities of Daily Living, Acute Disease, Aged, Arm, Exercise Therapy, Female, Humans, Male, Middle Aged, Pain, Posture, Prospective Studies, Regression Analysis, Restraint, Physical, Severity of Illness Index, Shoulder Joint, Multivariate Analysis, Range of Motion, Articular, Treatment Outcome, Patient Selection, Hand Strength, Recovery of Function, Stroke

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