The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Practice Guideline Update Recommendations Summary: Disorders of Consciousness
Open accessAbstract
OBJECTIVE: To update the 1995 American Academy of Neurology (AAN) practice parameter on persistent vegetative state and the 2002 case definition on minimally conscious state (MCS) and provide care recommendations for patients with prolonged disorders of consciousness (DoC). METHODS: Recommendations were based on systematic review evidence, related evidence, care principles, and inferences using a modified Delphi consensus process according to the AAN 2011 process manual, as amended. RECOMMENDATIONS: Clinicians should identify and treat confounding conditions, optimize arousal, and perform serial standardized assessments to improve diagnostic accuracy in adults and children with prolonged DoC (Level B). Clinicians should counsel families that for adults, MCS (vs vegetative state [VS]/ unresponsive wakefulness syndrome [UWS]) and traumatic (vs nontraumatic) etiology are associated with more favorable outcomes (Level B). When prognosis is poor, long-term care must be discussed (Level A), acknowledging that prognosis is not universally poor (Level B). Structural MRI, SPECT, and the Coma Recovery Scale-Revised can assist prognostication in adults (Level B); no tests are shown to improve prognostic accuracy in children. Pain always should be assessed and treated (Level B) and evidence supporting treatment approaches discussed (Level B). Clinicians should prescribe amantadine (100-200 mg bid) for adults with traumatic VS/UWS or MCS (4-16 weeks post injury) to hasten functional recovery and reduce disability early in recovery (Level B). Family counseling concerning children should acknowledge that natural history of recovery, prognosis, and treatment are not established (Level B). Recent evidence indicates that the term chronic VS/UWS should replace permanent VS, with duration specified (Level B). Additional recommendations are included.
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Self-citationMedical Aspects of the Persistent Vegetative State
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Seel, R. T., Sherer, M., Whyte, J., Katz, D. I., Giacino, J. T., Rosenbaum, A. M., Hammond, F. M., Kalmar, K., Pape, T. L.-B., Zafonte, R., et al. (2010) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2010.07.218 · Cited by 625
Self-citationSitt, J. D., King, J.-R., El Karoui, I., Rohaut, B., Faugeras, F., Gramfort, A., Cohen, L., Sigman, M., Dehaene, S., & Naccache, L. (2014) · Brain · doi:10.1093/brain/awu141 · Cited by 608
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Self-citationAccuracy of diagnosis of persistent vegetative state
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Cited by
Therapeutic interventions in patients with prolonged disorders of consciousness
Thibaut, A., Schiff, N., Giacino, J., Laureys, S., & Gosseries, O. (2019) · The Lancet Neurology · doi:10.1016/s1474-4422(19)30031-6 · Cited by 429
Self-citationRohaut, B., Calligaris, C., Hermann, B., Perez, P., Faugeras, F., Raimondo, F., King, J. R., Engemann, D., Marois, C., Le Guennec, L., et al. (2024) · Nature Medicine · doi:10.1038/s41591-024-03019-1 · Cited by 62
Uncovering Consciousness in Unresponsive ICU Patients: Technical, Medical and Ethical Considerations
Rohaut, B., Eliseyev, A., & Claassen, J. (2019) · Critical Care · doi:10.1186/s13054-019-2370-4 · Cited by 59
Farisco, M., & Changeux, J.-P. (2023) · Neuroscience of Consciousness · doi:10.1093/nc/niad016 · Cited by 29
Metadata
- Authors
- Giacino, J. T., Katz, D. I., Schiff, N. D., Whyte, J., Ashman, E. J., Ashwal, S., Barbano, R., Hammond, F. M., Laureys, S., Ling, G. S. F., Nakase-Richardson, R., Seel, R. T., Yablon, S., Getchius, T. S. D., Gronseth, G. S., & Armstrong, M. J.
- Venue
- Archives of Physical Medicine and Rehabilitation
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 99
- Issue
- 9
- Pages
- 1699-1709
- ISSN
- 0003-9993 (ISSN-L)
- OpenAlex
- W3203598446
- Cited by
- 269
- References
- 36
- FWCI
- 17.56
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Giacino, J. T., Katz, D. I., Schiff, N. D., Whyte, J., Ashman, E. J., Ashwal, S., Barbano, R., Hammond, F. M., Laureys, S., Ling, G. S. F., Nakase-Richardson, R., Seel, R. T., Yablon, S., Getchius, T. S. D., Gronseth, G. S., & Armstrong, M. J. (2018). Practice Guideline Update Recommendations Summary: Disorders of Consciousness. Archives of Physical Medicine and Rehabilitation. https://doi.org/10.1016/j.apmr.2018.07.001
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