Uncovering Consciousness in Unresponsive ICU Patients: Technical, Medical and Ethical Considerations
Open accessAbstract
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2019. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2019 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901 .
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Tubulin is partially composed of chromophores such as tryptophan, arranged in a manner similar to photosynthetic systems in plants and bacteria, which have been surmised to support coherent quantum effects.
“The specific composition of tubulin has also lent strength to quantum models of neural processing due to the fact that it is partially composed of chromophores such as tryptophan, arranged in a manner similar to photosynthetic systems in plants and bacteria 43,44 , which have been surmised to support coherent quantum effects.”
From Quantum effects in the brain: A review (2020) · cites this paper as [44]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The minimally conscious state: Definition and diagnostic criteria
Giacino, J. T., Ashwal, S., Childs, N., Cranford, R., Jennett, B., Katz, D. I., Kelly, J. P., Rosenberg, J. H., Whyte, J., Zafonte, R. D., et al. (2002) · Neurology · doi:10.1212/wnl.58.3.349 · Cited by 2,422 · see citing works
Detecting awareness in the vegetative state
Owen, A. M., Coleman, M. R., Boly, M., Davis, M. H., Laureys, S., & Pickard, J. D. (2006) · Science · doi:10.1126/science.1130197 · Cited by 1,978 · see citing works
Willful Modulation of Brain Activity in Disorders of Consciousness
Monti, M. M., Vanhaudenhuyse, A., Coleman, M. R., Boly, M., Pickard, J. D., Tshibanda, L., Owen, A. M., & Laureys, S. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0905370 · Cited by 1,469 · see citing works
Unresponsive wakefulness syndrome: a new name for the vegetative state or apallic syndrome
the European Task Force on Disorders of Consciousness, Laureys, S., Celesia, G. G., Cohadon, F., Lavrijsen, J. C. M., León‐Carrión, J., Sannita, W. G., Sazbon, L., Schmutzhard, E., von Wild, K. R. H., et al. (2010) · BMC Medicine · doi:10.1186/1741-7015-8-68 · Cited by 1,287 · see citing works
A theoretically based index of consciousness independent of sensory processing and behavior
Casali, A. G., Gosseries, O., Rosanova, M., Boly, M., Sarasso, S., Casali, K. R., Casarotto, S., Bruno, M.-A., Laureys, S., Tononi, G., et al. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3006294 · Cited by 1,246 · see citing works
PERSISTENT VEGETATIVE STATE AFTER BRAIN DAMAGE
Jennett, B., & Plum, F. (1972) · The Lancet · doi:10.1016/s0140-6736(72)90242-5 · Cited by 1,230 · see citing works
Outcome of delirium in critically ill patients: systematic review and meta-analysis
Salluh, J. I., Wang, H., Schneider, E. B., Nagaraja, N., Yenokyan, G., Damluji, A. A., Serafim, R. B., & Stevens, R. D. (2015) · BMJ · doi:10.1136/bmj.h2538 · Cited by 1,057 · see citing works
Practice guideline update recommendations summary: Disorders of consciousness
Giacino, J. T., Katz, D. I., Schiff, N. D., Whyte, J., Ashman, E. J., Ashwal, S., Barbano, R. L., Hammond, F. M., Laureys, S., Ling, G. S. F., et al. (2018) · Neurology · doi:10.1212/wnl.0000000000005926 · Cited by 785 · see citing works
Neural signature of the conscious processing of auditory regularities
Bekinschtein, T. A., Dehaene, S., Rohaut, B., Tadel, F., Cohen, L., & Naccache, L. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809667106 · Cited by 738 · see citing works
Self-citationBedside detection of awareness in the vegetative state: a cohort study
Cruse, D., Chennu, S., Chatelle, C., Bekinschtein, T. A., Fernández‐Espejo, D., Pickard, J. D., Laureys, S., & Owen, A. M. (2011) · The Lancet · doi:10.1016/s0140-6736(11)61224-5 · Cited by 714 · see citing works
Pfurtscheller, G. (2010) · Frontiers in Neuroscience · doi:10.3389/fnpro.2010.00003 · Cited by 673 · see citing works
Bruno, M., Vanhaudenhuyse, A., Thibaut, A., Moonen, G., & Laureys, S. (2011) · Journal of Neurology · doi:10.1007/s00415-011-6114-x · Cited by 670 · see citing works
Sitt, J. D., King, J.-R., El Karoui, I., Rohaut, B., Faugeras, F., Gramfort, A., Cohen, L., Sigman, M., Dehaene, S., & Naccache, L. (2014) · Brain · doi:10.1093/brain/awu141 · Cited by 608 · see citing works
Self-citationStender, J., Gosseries, O., Bruno, M.-A., Charland-Verville, V., Vanhaudenhuyse, A., Demertzi, A., Chatelle, C., Thonnard, M., Thibaut, A., Heine, L., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60042-8 · Cited by 550 · see citing works
The Diagnosis of Stupor and Coma
Poser, C. M. (1981) · JAMA · doi:10.1001/jama.1981.03310320080042 · Cited by 548 · see citing works
Turgeon, A. F., Lauzier, F., Simard, J.-F., Scales, D. C., Burns, K. E. A., Moore, L., Zygun, D. A., Bernard, F., Meade, M. O., Dung, T. C., et al. (2011) · Canadian Medical Association Journal · doi:10.1503/cmaj.101786 · Cited by 489 · see citing works
Stratification of unresponsive patients by an independently validated index of brain complexity
Casarotto, S., Comanducci, A., Rosanova, M., Sarasso, S., Fecchio, M., Napolitani, M., Pigorini, A., G. Casali, A., Trimarchi, P. D., Boly, M., et al. (2016) · Annals of Neurology · doi:10.1002/ana.24779 · Cited by 487 · see citing works
Cognitive Motor Dissociation Following Severe Brain Injuries
Schiff, N. D. (2015) · JAMA Neurology · doi:10.1001/jamaneurol.2015.2899 · Cited by 477 · see citing works
Comprehensive systematic review update summary: Disorders of consciousness
Giacino, J. T., Katz, D. I., Schiff, N. D., Whyte, J., Ashman, E. J., Ashwal, S., Barbano, R. L., Hammond, F. M., Laureys, S., Ling, G. S. F., et al. (2018) · Neurology · doi:10.1212/wnl.0000000000005928 · Cited by 432 · see citing works
Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients
Athena Demertzi, A., Antonopoulos, G., Heine, L., Voss, H. U., Crone, J. S., Angeles, C. D. L., Bahri, M. A., Perri, C. D., Vanhaudenhuyse, A., Charland‐Verville, V., et al. (2015) · Brain · doi:10.1093/brain/awv169 · Cited by 384 · see citing works
Early detection of consciousness in patients with acute severe traumatic brain injury
Edlow, B. L., Chatelle, C., Spencer-Salmon, C. A., Chu, C. J., Bodien, Y. G., O’Connor, K. L., Hirschberg, R. E., Hochberg, L. R., Giacino, J. T., Rosenthal, E. S., et al. (2017) · Brain · doi:10.1093/brain/awx176 · Cited by 377 · see citing works
Information Sharing in the Brain Indexes Consciousness in Noncommunicative Patients
King, J.-R., Sitt, J. D., Faugeras, F., Rohaut, B., El Karoui, I., Cohen, L., Naccache, L., & Dehaene, S. (2013) · Current Biology · doi:10.1016/j.cub.2013.07.075 · Cited by 370 · see citing works
Self-citationChennu, S., Annen, J., Wannez, S., Thibaut, A., Chatelle, C., Cassol, H., Martens, G., Schnakers, C., Gosseries, O., Menon, D., et al. (2017) · Brain · doi:10.1093/brain/awx163 · Cited by 339 · see citing works
Kondziella, D., Friberg, C. K., Frøkjær, V. G., Fabricius, M. E., & Møller, K. (2015) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2015-310958 · Cited by 320 · see citing works
Practice Guideline Update Recommendations Summary: Disorders of Consciousness
Giacino, J. T., Katz, D. I., Schiff, N. D., Whyte, J., Ashman, E. J., Ashwal, S., Barbano, R. L., Hammond, F. M., Laureys, S., Ling, G. S. F., et al. (2018) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2018.07.001 · Cited by 272 · see citing works
Hong, K.-S., & Khan, M. J. (2017) · Frontiers in Neurorobotics · doi:10.3389/fnbot.2017.00035 · Cited by 267 · see citing works
Determination of awareness in patients with severe brain injury using EEG power spectral analysis
Goldfine, A. M., Victor, J. D., Conte, M. M., Bardin, J. C., & Schiff, N. D. (2011) · Clinical Neurophysiology · doi:10.1016/j.clinph.2011.03.022 · Cited by 240 · see citing works
Nurse-Patient Communication Interactions in the Intensive Care Unit
Happ, M. B., Garrett, K. L., Thomas, D. D., Tate, J. A., GEORGE, E. L., Houze, M. P., Radtke, J., & Sereika, S. M. (2011) · American Journal of Critical Care · doi:10.4037/ajcc2011433 · Cited by 239 · see citing works
Minimally conscious state or cortically mediated state?
Naccache, L. (2018) · Brain · doi:10.1093/brain/awx324 · Cited by 181 · see citing works
The Diagnosis of Stupor and Coma, 3rd ed
MARSDEN, C. D. (1981) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.44.3.270-a · Cited by 156 · see citing works
Characterization of EEG signals revealing covert cognition in the injured brain
Curley, W. H., Forgacs, P. B., Voss, H. U., Conte, M. M., & Schiff, N. D. (2018) · Brain · doi:10.1093/brain/awy070 · Cited by 144 · see citing works
Constructing an ethical stereotaxy for severe brain injury: balancing risks, benefits and access
Fins, J. J. (2003) · Nature reviews. Neuroscience · doi:10.1038/nrn1079 · Cited by 137 · see citing works
Brain-Computer Interface: Current and Emerging Rehabilitation Applications
Daly, J. J., & Huggins, J. E. (2015) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2015.01.007 · Cited by 124 · see citing works
Factors related to the emotional responses of intubated patients to being unable to speak
Menzel, L. K. (1998) · Heart & Lung · doi:10.1016/s0147-9563(98)90036-x · Cited by 121 · see citing works
SSEPs and prognosis in postanoxic coma
Zandbergen, E. G. J., Koelman, J. H. T. M., de Haan, R. J., & Hijdra, A. (2006) · Neurology · doi:10.1212/01.wnl.0000230162.35249.7f · Cited by 120 · see citing works
Ethical, palliative, and policy considerations in disorders of consciousness
Fins, J. J., & Bernat, J. L. (2018) · Neurology · doi:10.1212/wnl.0000000000005927 · Cited by 115 · see citing works
Brain-Machine Interface (BMI) in paralysis
Chaudhary, U., Birbaumer, N., & Curado, M. R. (2015) · Annals of Physical and Rehabilitation Medicine · doi:10.1016/j.rehab.2014.11.002 · Cited by 112 · see citing works
Relationship between etiology and covert cognition in the minimally conscious state
Cruse, D., Chennu, S., Chatelle, C., Fernández‐Espejo, D., Bekinschtein, T. A., Pickard, J. D., Laureys, S., & Owen, A. M. (2012) · Neurology · doi:10.1212/wnl.0b013e318249f764 · Cited by 111 · see citing works
Harvey, D., Butler, J., Groves, J., Manara, A. R., Menon, D. K., Thomas, E., & Wilson, M. (2017) · British Journal of Anaesthesia · doi:10.1016/j.bja.2017.10.002 · Cited by 108 · see citing works
Hosker, C., & Ward, D. (2017) · BMJ · doi:10.1136/bmj.j2047 · Cited by 106 · see citing works
Claassen, J., Velazquez, A. G., Meyers, E. E., Witsch, J., Falo, M. C., Park, S., Agarwal, S., Schmidt, J. M., Schiff, N. D., Sitt, J. D., et al. (2016) · Annals of Neurology · doi:10.1002/ana.24752 · Cited by 102 · see citing works
Self-citationReforming the taxonomy in disorders of consciousness
Bayne, T., Hohwy, J., & Owen, A. M. (2017) · Annals of Neurology · doi:10.1002/ana.25088 · Cited by 94 · see citing works
Wijdicks, E. F. M., Kramer, A. A., Rohs, T. J., Hanna, S., Sadaka, F. G., O’Brien, J., Bible, S., Dickess, S. M., & Foss, M. (2014) · Critical Care Medicine · doi:10.1097/ccm.0000000000000707 · Cited by 82 · see citing works
Nonvocal Ventilated Patients Perceptions of Being Understood
Carroll, S. M. C. (2004) · Western Journal of Nursing Research · doi:10.1177/0193945903259462 · Cited by 79 · see citing works
Brain communication in the locked-in state
Massari, D. D., Ruf, C. A., Furdea, A., Matuz, T., van der Heiden, L., Halder, S., Silvoni, S., & Birbaumer, N. (2013) · Brain · doi:10.1093/brain/awt102 · Cited by 77 · see citing works
Rohaut, B., & Claassen, J. (2017) · British Journal of Anaesthesia · doi:10.1016/j.bja.2017.11.007 · Cited by 65 · see citing works
Self-citationDreaming and awareness during dexmedetomidine- and propofol-induced unresponsiveness
Radek, L., Kallionpää, R., Karvonen, M., Scheinin, A., Maksimow, A. T., Långsjö, J., Kaisti, K. K., Vahlberg, T. J., Revonsuo, A., Scheinin, H., et al. (2018) · British Journal of Anaesthesia · doi:10.1016/j.bja.2018.03.014 · Cited by 53 · see citing works
Feasibility of an EEG-based brain-computer interface in the intensive care unit
Chatelle, C., Spencer-Salmon, C. A., Cash, S. S., Hochberg, L. R., & Edlow, B. L. (2018) · Clinical Neurophysiology · doi:10.1016/j.clinph.2018.04.747 · Cited by 45 · see citing works
Disentangling conscious from unconscious cognitive processing with event-related EEG potentials
Rohaut, B., & Naccache, L. (2017) · Revue Neurologique · doi:10.1016/j.neurol.2017.08.001 · Cited by 44 · see citing works
Self-citationEliseyev, A., Auboiroux, V., Costecalde, T., Langar, L., Charvet, G., Mestais, C., Aksenova, T., & Benabid, A.-L. (2017) · Scientific Reports · doi:10.1038/s41598-017-16579-9 · Cited by 42 · see citing works
Self-citationArterial spin labeling and altered cerebral blood flow patterns in the minimally conscious state
Liu, A. A., Voss, H. U., Dyke, J. P., Heier, L., & Schiff, N. D. (2011) · Neurology · doi:10.1212/wnl.0b013e318233b229 · Cited by 41 · see citing works
Nosologic considerations in disorders of consciousness
Bernat, J. L. (2017) · Annals of Neurology · doi:10.1002/ana.25089 · Cited by 24 · see citing works
Dehzangi, O., & Farooq, M. (2018) · BioMed Research International · doi:10.1155/2018/9796238 · Cited by 22 · see citing works
Flagged first, then by citations
2 of the 55 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies
Edlow, B. L., Claassen, J., Schiff, N. D., & Greer, D. M. (2020) · Nature Reviews Neurology · doi:10.1038/s41582-020-00428-x · Cited by 744 · see citing works
Self-citationKondziella, D., Bender, A., Diserens, K., van Erp, W. S., Estraneo, A., Formisano, R., Laureys, S., Naccache, L., Öztürk, Ş., Rohaut, B., et al. (2020) · European Journal of Neurology · doi:10.1111/ene.14151 · Cited by 735 · see citing works
Self-citationClinical Aspects of Palliative Sedation in Prospective Studies. A Systematic Review
Arantzamendi, M., Belar, A., Payne, S. A., Rijpstra, M., Preston, N. J., Menten, J. J., der Elst, M. V., Radbruch, L., Hasselaar, J. G. J., & Centeno, C. (2020) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2020.09.022 · Cited by 134 · see citing works
Electroencephalogram in the intensive care unit: a focused look at acute brain injury
Alkhachroum, A. M., Appavu, B. L., Egawa, S., Foreman, B. P., Gaspard, N., Gilmore, E. J., Hirsch, L. J., Kurtz, P., Lambrecq, V., Kromm, J. A., et al. (2022) · Intensive Care Medicine · doi:10.1007/s00134-022-06854-3 · Cited by 117 · see citing works
Self-citationQuantum effects in the brain: A review
Adams, B., & Petruccione, F. (2020) · AVS Quantum Science · doi:10.1116/1.5135170 · Cited by 80 · see citing works
Cognitive Motor Dissociation: Gap Analysis and Future Directions
Claassen, J., Kondziella, D., Alkhachroum, A. M., Diringer, M. N., Edlow, B. L., Fins, J. J., Gosseries, O., Hannawi, Y., Rohaut, B., Caroline Schnakers, A., et al. (2023) · Neurocritical Care · doi:10.1007/s12028-023-01769-3 · Cited by 64 · see citing works
Self-citationRohaut, B., Calligaris, C., Hermann, B., Perez, P., Faugeras, F., Raimondo, F., King, J. R., Engemann, D., Marois, C., Le Guennec, L., et al. (2024) · Nature Medicine · doi:10.1038/s41591-024-03019-1 · Cited by 62 · see citing works
Self-citationPrognostication after cardiac arrest: how EEG and evoked potentials may improve the challenge
Benghanem, S., Pruvost‐Robieux, E., Bouchereau, E., Gavaret, M., & Cariou, A. (2022) · Annals of Intensive Care · doi:10.1186/s13613-022-01083-9 · Cited by 54 · see citing works
Improving Diagnosis and Prognosis in Acute Severe Brain Injury: A Multimodal Imaging Protocol
Kazazian, K., Norton, L. E., Laforge, G., Abdalmalak, A., Gofton, T. E., Debicki, D., Slessarev, M., Hollywood, S., Lawrence, K. S., & Owen, A. M. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.757219 · Cited by 45 · see citing works
Young, M. J., Edlow, B. L., & Bodien, Y. G. (2024) · Neurorehabilitation · doi:10.3233/nre-230123 · Cited by 33 · see citing works
Kazazian, K., Abdalmalak, A., Junior, S. L. N., Norton, L. E., Ardakani, R., Kolisnyk, M., Gofton, T. E., Mesquita, R. C., Owen, A. M., & Debicki, D. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2402723121 · Cited by 31 · see citing works
Rohaut, B., Doyle, K. W., Reynolds, A. S., Igwe, K. C., Couch, C., Matory, A., Rizvi, B. M., Roh, D. J., Velazquez, A. G., Megjhani, M., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-41042-2 · Cited by 30 · see citing works
Self-citationEEG Correlates of Language Function in Traumatic Disorders of Consciousness
Chatelle, C., Rosenthal, E. S., Bodien, Y. G., Spencer-Salmon, C. A., Giacino, J. T., & Edlow, B. L. (2020) · Neurocritical Care · doi:10.1007/s12028-019-00904-3 · Cited by 26 · see citing works
Kim, K. A., Kim, H., Ha, E. J., Yoon, B. C., & Kim, D. (2024) · Journal of Korean Neurosurgical Society · doi:10.3340/jkns.2023.0195 · Cited by 24 · see citing works
The intractable problems with brain death and possible solutions
Joffe, A. R., Khaira, G. K., & de Caen, A. R. (2021) · Philosophy Ethics and Humanities in Medicine · doi:10.1186/s13010-021-00107-9 · Cited by 25 · see citing works
Disorders of consciousness terminology: history, evolution and future directions
Zasler, N. D., Aloisi, M., Contrada, M., & Formisano, R. (2019) · Brain Injury · doi:10.1080/02699052.2019.1656821 · Cited by 21 · see citing works
Quantitative EEG signatures of delirium and coma in mechanically ventilated ICU patients
Roberson, S. W., Azeez, N. A., Fulton, J. N., Zhang, K. C., Lee, A. X. T., Ye, F., Pandharipande, P. P., Brummel, N. E., Patel, M. B., & Ely, E. W. (2022) · Clinical Neurophysiology · doi:10.1016/j.clinph.2022.11.012 · Cited by 21 · see citing works
Detecting awareness after acute brain injury
Kazazian, K., Edlow, B. L., & Owen, A. M. (2024) · The Lancet Neurology · doi:10.1016/s1474-4422(24)00209-6 · Cited by 20 · see citing works
van Dijck, J. T. J. M., Bartels, R., Lavrijsen, J. C. M., Ribbers, G. M., Kompanje, E. J. O., & Peul, W. C. (2019) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000671 · Cited by 18 · see citing works
Development of a brain-computer interface for patients in the critical care setting
Eliseyev, A., Gonzales, I. J., Le, A., Doyle, K. W., Egbebike, J. A., Velazquez, A. G., Agarwal, S., Roh, D. J., Park, S., Connolly, E. S., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0245540 · Cited by 18 · see citing works
Self-citationCovert Consciousness in the ICU
Edlow, B. L., & Menon, D. K. (2024) · Critical Care Medicine · doi:10.1097/ccm.0000000000006372 · Cited by 17 · see citing works
Classifying Disorders of Consciousness: Past, Present, and Future
Kondziella, D., & Stevens, R. D. (2022) · Seminars in Neurology · doi:10.1055/a-1883-1021 · Cited by 16 · see citing works
Schey, J. E., Schoch, M., & Kerr, D. C. (2024) · Neurocritical Care · doi:10.1007/s12028-024-02150-8 · Cited by 15 · see citing works
Unmasking Covert Language Processing in the Intensive Care Unit with Electroencephalography
Edlow, B. L., & Naccache, L. (2021) · Annals of Neurology · doi:10.1002/ana.26030 · Cited by 15 · see citing works
Naçi, L., & Owen, A. M. (2022) · Seminars in Neurology · doi:10.1055/a-1892-1715 · Cited by 13 · see citing works
Functional and structural brain connectivity in disorders of consciousness
Altmayer, V., Sangaré, A., Calligaris, C., Puybasset, L., Perlbarg, V., Naccache, L., Sitt, J. D., & Rohaut, B. (2024) · Brain Structure and Function · doi:10.1007/s00429-024-02839-8 · Cited by 10 · see citing works
Self-citationKazazian, K., Norton, L. E., Gofton, T. E., Debicki, D., & Owen, A. M. (2020) · Brain Sciences · doi:10.3390/brainsci10090604 · Cited by 9 · see citing works
Understanding, detecting, and stimulating consciousness recovery in the ICU
Kondziella, D., Amiri, M., Othman, M., Jakobsen, E. W., Jansen, T., & Møller, K. (2022) · Acta Neurochirurgica · doi:10.1007/s00701-022-05378-5 · Cited by 9 · see citing works
Петрова, М. В., Shevelev, O. A., Yuriev, M. Y., Zhdanova, M. A., Kostenkova, I. Z., & Kanarskii, M. M. (2022) · General Reanimatology · doi:10.15360/1813-9779-2022-2-45-52 · Cited by 8 · see citing works
Self-processing in coma, unresponsive wakefulness syndrome and minimally conscious state
Ferré, F., Heine, L., Naboulsi, E., Gobert, F., Beaudoin‐Gobert, M., Dailler, F., Buffières, W., Corneyllie, A., Sarton, B., Riu, B., et al. (2023) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2023.1145253 · Cited by 8 · see citing works
Disorders of Consciousness Rehabilitation
Young, M. J. (2023) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2023.06.016 · Cited by 8 · see citing works
Classification of Level of Consciousness in a Neurological ICU Using Physiological Data
Gomez, L., Shen, Q., Doyle, K. W., Vrosgou, A., Velazquez, A. G., Megjhani, M., Ghoshal, S., Roh, D. J., Agarwal, S., Park, S., et al. (2022) · Neurocritical Care · doi:10.1007/s12028-022-01586-0 · Cited by 7 · see citing works
Self-citationFunctional Neuroimaging in Patients With Disorders of Consciousness: Caution Advised
Elwell, C. E. (2023) · Journal of Neurosurgical Anesthesiology · doi:10.1097/ana.0000000000000920 · Cited by 6 · see citing works
Андреевич, Б. В., Ильина, К. А., & Ryabinkina, Y. V. (2021) · Annals of Clinical and Experimental Neurology · doi:10.54101/acen.2021.3.6 · Cited by 6 · see citing works
Shining Light on the Human Brain: An Optical BCI for Communicating with Patients with Brain Injuries
Abdalmalak, A., Laforge, G., Yip, L. C. M., Milej, D. F., González-Lara, L. E., Anazodo, U., Owen, A. M., & Lawrence, K. S. (2020) · Conference proceedings/Conference proceedings - IEEE International Conference on Systems, Man, and Cybernetics · doi:10.1109/smc42975.2020.9283123 · Cited by 6 · see citing works
Knapik, P., Borowik, D., Cieśla, D., & Trejnowska, E. (2021) · PLoS ONE · doi:10.1371/journal.pone.0253225 · Cited by 5 · see citing works
Advanced neuromonitoring techniques for medical and neurological ICU patients
Eshraghi, R., Yazdani, M. S., Bahrami, A., Amani‐Beni, R., Darouei, B., Mokhtari, M., & Hashemian, S. M. R. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111513 · Cited by 4 · see citing works
Reliability and validation of the Japanese version of the coma recovery scale-revised (CRS-R)
Kitano, T., Giacino, J. T., Bodien, Y. G., Waters, A. B., Hioki, D., Shinya, J., Nakayama, T., & Ohgi, S. (2024) · Brain Injury · doi:10.1080/02699052.2024.2309549 · Cited by 4 · see citing works
Neurological and systemic effects of cocaine toxicity: A case report and review of the literature
Hong, Z. M., & Kromm, J. A. (2024) · Medicine International · doi:10.3892/mi.2024.196 · Cited by 3 · see citing works
Nguyen, D., & Zainer, C. M. (2025) · The Linacre Quarterly · doi:10.1177/00243639251317690 · Cited by 3 · see citing works
Fu, J., Wu, Y., Feng, H., Chen, F., Feng, H., Pan, H., & Wang, H. (2025) · BMC Neurology · doi:10.1186/s12883-025-04189-2 · Cited by 2 · see citing works
Cortical signatures linked to behavior quantitatively track arousal levels
Gao, S., Bibineyshvili, Y., Safavynia, S. A., Calderón-Martínez, J., Grinspan, Z. M., & Calderon, D. P. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2413789122 · Cited by 2 · see citing works
Low frequency oscillations reflect neurovascular coupling and disappear after cerebral death
Schulthess, S., Friedl, S., Narula, G., Brandi, G., Willms, J. F., Keller, E., & Bicciato, G. (2024) · Scientific Reports · doi:10.1038/s41598-024-61819-4 · Cited by 2 · see citing works
Electrophysiology in disorders of consciousness
Ridha, M., Kumar, A., & Claassen, J. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-13408-1.00013-0 · Cited by 2 · see citing works
Self-citationHabibzadeh, H., Zhou, O., Norton, J. J. S., Vaughan, T. M., & Zois, D. (2021) · IEEE International Conference on Acoustics Speech and Signal Processing · doi:10.1109/icassp39728.2021.9414075 · Cited by 2 · see citing works
Disturbi della coscienza, coma
Hermann, B., Simony, M., & Rohaut, B. (2023) · EMC - Neurologia · doi:10.1016/s1634-7072(23)48428-0 · Cited by 1 · see citing works
Self-citationReflections on Consciousness in Intensive Care
Broomé, M., & Mathiesen, T. I. (2025) · Acta Paediatrica · doi:10.1111/apa.70372 · Cited by 1 · see citing works
Soulier, T., Colliot, O., Ayache, N., & Rohaut, B. (2023) · Anaesthesia Critical Care & Pain Medicine · doi:10.1016/j.accpm.2023.101301 · Cited by 1 · see citing works
Self-citationBernat, J. L. (2019) · Cambridge Quarterly of Healthcare Ethics · doi:10.1017/s0963180119000562 · Cited by 1 · see citing works
“DoC DoC”, your attention please!
Rohaut, B. (2022) · Clinical Neurophysiology · doi:10.1016/j.clinph.2022.10.007 · Cited by 1 · see citing works
Self-citationWhat criteria for neuropronostication: consciousness or ability? The neuro-intensivist’s dilemma
Engrand, N., Nicolas-Robin, A., Trouiller, P., & Welschbillig, S. (2024) · Critical Care · doi:10.1186/s13054-024-05098-5 · Cited by 1 · see citing works
General Discussion and Future Perspectives
Cassarini, C. (2019) · CRC Press eBooks · doi:10.1201/9780429448300-7
Neuro-prognostication: Don’t forget that time is brain!
Bouchereau, E., & Degos, V. (2019) · Anaesthesia Critical Care & Pain Medicine · doi:10.1016/j.accpm.2019.09.002
Éthique et temporalité en neuroréanimation
Bouchereau, E., & Degos, V. (2019) · Anesthésie & Réanimation · doi:10.1016/j.anrea.2019.09.008
How to deal an unconscious patient in ICU
Sayeed, A. (2023) · Z H Sikder Women’s Medical College Journal · doi:10.47648/zhswmcj.2023.v0502.09
Troubles de la conscience, coma
Hermann, B., Simony, M., & Rohaut, B. (2023) · HAL · doi:10.1016/s0246-0378(23)50453-x
Self-citationYoo, D., Tae, Y., Cho, K., Je, H. G., Kim, D., Son, B., Ju, M. H., Lee, C.-H., Lee, S., Kim, T., et al. (2025) · medRxiv · doi:10.1101/2025.01.10.25320368
Novel diagnostic and therapeutic approaches for patients suffering from disorders of consciousness
Hermann, B. (2019) · theses.fr (ABES) · doi:10.70675/e8620819z412fz4bd4z8475z998a979bfe82
Spontaneous slow waves index multiple dimensions of recovery in Disorders of ConsciousnessPreprint
Ruyant-Belabbas, A., Boullet, A., Manasova, D., Coz, A. L., Denis-Valente, M., Lejeune, F., Sitt, J. D., Naccache, L., Rohaut, B., & Andrillon, T. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.30.755786
Self-citation
- Authors
- Rohaut, B., Eliseyev, A., & Claassen, J.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Columbia University (US)
- Columbia University Irving Medical Center (US)
- Corresponding author
- Claassen, Jan
- Venue
- Critical Care
- Published
- 2019-03-09
- Volume
- 23
- Issue
- 1
- Pages
- 78-78
- ISSN
- 1364-8535 (ISSN-L)
- PMC
- PMC6408788
- OpenAlex
- W2924635711
- Cited by
- 59
- References
- 55
- Citations by year
- 2026: 1 · 2025: 7 · 2024: 12 · 2023: 8 · 2022: 9 · 2021: 7 · 2020: 7 · 2019: 8
- FWCI
- 1.13
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Critical Care (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- HAL (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Science Foundation (1347119)
- James S. McDonnell Foundation
- Dana Foundation
- Philippe Foundation
- National Institutes of Health
- U.S. National Library of Medicine (R01LM011826)
- Topics
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Keywords
- consciousness, unresponsive patients, intensive care unit, medical ethics, brain death determination, vegetative state, minimally conscious state, end-of-life decisions, neurocritical care
- MeSH terms
- Brain Injuries, Consciousness, Consciousness Disorders, Decision Support Techniques, Humans, Intensive Care Units, Persistent Vegetative State
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review