CoChat
Sign Up
Cited by 37Treatment of Major DepressionSchizophrenia research and treatmentBipolar Disorder and Treatment

Clinical correlates of age of onset in psychotic depression

Gournellis, Rossetos, Oulis, Panagiotis, Rizos, Emmanuel, Chourdaki, Evgenia, Gouzaris, Agis, Lykouras, Lefteris·2011·Archives of Gerontology and Geriatrics
DOI 10.1016/j.archger.2010.02.007
Open this paper in CoChat — free account

Abstract

The issue whether the clinical characteristics of unipolar psychotic major depression (PMD) vary according to the age of onset remains still unclear. Thus, the aim of this study was to assess comparatively a broad set of clinical characteristics of three groups of PMD patients, namely young early-onset (n=30), elderly early-onset (n=34) and elderly late-onset (n=35). Ninety-nine inpatients suffering from DSM-IV unipolar PMD were assessed on the basis of Structured Clinical Interview for DSM-IV (SCID-IV), Hamilton Rating Scale for Depression (HRSD) and a physical impairment rating scale. The elderly late-onset patients suffered from overall more severe depression compared to both early-onset ones, more psychic anxiety compared to elderly early-onset patients and more gastrointestinal symptoms compared to young early-onset patients. Additionally, they expressed significantly more frequently delusions of somatic content and higher scores on the HRSD item of hypochondriasis than their young early-onset counterparts. The group of elderly early-onset PMD patients was found to hold an intermediate position between the young early-onset and elderly late-onset PMD patients with regard to hypochondriacal ideation, gastrointestinal symptoms and delusions of somatic, guilt, and paranoid content. Their stability of delusional content across successive episodes was found to extend into old age. Nevertheless, they expressed additional somatic delusions. Overall, the findings of the present study suggest considerable differences between young early-onset, elderly early-onset and elderly late-onset PMD patients with respect to their clinical features.

Integrity signals

Registry

Crossref · 10.1016/j.archger.2010.02.007

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Gournellis, R., Oulis, P., Rizos, E., Chourdaki, E., Gouzaris, A., & Lykouras, L.
Affiliations
  • National and Kapodistrian University of Athens (GR)
  • The General Hospital of Heraklion "Venizeleio-Pananio" (GR)
Corresponding author
Gournellis, Rossetos
ORCID
Venue
Archives of Gerontology and Geriatrics
Publisher
Elsevier BV
Published
2011-01
Volume
52
Issue
1
Pages
94-98
ISSN
0167-4943 (ISSN-L)
DOI
10.1016/j.archger.2010.02.007
OpenAlex
W2004755440
Cited by
37
References
39
Citations by year
2026: 1 · 2024: 1 · 2023: 1 · 2022: 6 · 2021: 2 · 2019: 2 · 2018: 4 · 2017: 5 · 2016: 1 · 2015: 3 · 2014: 3 · 2013: 2 · 2012: 6
FWCI
1.88
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Archives of Gerontology and Geriatrics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords
psychotic depression, age of onset, early-onset depression, late-onset depression, elderly patients, somatic delusions, health anxiety, gastrointestinal symptoms, psychic anxiety, depression severity, persecutory delusions
MeSH terms
Affective Disorders, Psychotic, Age Factors, Aged, Delusions, Educational Status, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Recurrence, Retrospective Studies, Risk Factors, Sex Factors, Marital Status, Age of Onset

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review