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MicroRNA-455–3P as a peripheral biomarker and therapeutic target for mild cognitive impairment and Alzheimer’s disease

Islam, Md Ariful, Sultana, Omme Fatema, Bandari, Madhuri, Kshirsagar, Sudhir, Manna, Pulak R., Reddy, P. Hemachandra·2024·Ageing Research Reviews
DOI 10.1016/j.arr.2024.102459PMC PMC11383742
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  • miR-455-3p levels have been reported in brain tissue, CSF, plasma, fibroblasts, and lymphocytes from AD patients.

    “Among these species, miR-455-3p has emerged as a promising cross-tissue biomarker candidate; levels have been reported in brain tissue, CSF, plasma, fibroblasts, and lymphocytes from AD patients, and experimental studies suggest neuroprotective effects on synaptic and mitochondrial function (Islam et al., 2024; Kumar et al., 2017; Kumar et al., 2021; Swingler et al., 2022).”

    From Cell-specific MicroRNA networks orchestrate the pathogenesis of Alzheimer’s disease (2026) · cites this paper as Islam et al., 2024

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Cited by

Sorted by citations

Authors
Islam, M. A., Sultana, O. F., Bandari, M., Kshirsagar, S., Manna, P. R., & Reddy, P. H.
ORCID
Reddy, P. Hemachandra
Venue
Ageing Research Reviews
Publisher
Elsevier BV
Published
2024-09
Volume
100
Pages
102459
ISSN
1568-1637
DOI
10.1016/j.arr.2024.102459
PMC
PMC11383742
Cited by
29
References
10
Language
en
Licence
Funders
NIH (AG079264)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

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