Cited by 87Context-Aware Activity Recognition SystemsMedication Adherence and ComplianceNon-Invasive Vital Sign Monitoring

A wearable sensor system for medication adherence prediction

Kalantarian, Haik, Motamed, Babak, Alshurafa, Nabil, Sarrafzadeh, Majid·2016·Artificial Intelligence in Medicine

Abstract

Objective Studies have revealed that non-adherence to prescribed medication can lead to hospital readmissions, clinical complications, and other negative patient outcomes. Though many techniques have been proposed to improve patient adherence rates, they suffer from low accuracy. Our objective is to develop and test a novel system for assessment of medication adherence. Methods Recently, several smart pill bottle technologies have been proposed, which can detect when the bottle has been opened, and even when a pill has been retrieved. However, very few systems can determine if the pill is subsequently ingested or discarded. We propose a system for detecting user adherence to medication using a smart necklace, capable of determining if the medication has been ingested based on the skin movement in the lower part of the neck during a swallow. This, coupled with existing medication adherence systems that detect when medicine is removed from the bottle, can detect a broader range of use-cases with respect to medication adherence. Results Using Bayesian networks, we were able to correctly classify between chewable vitamins, saliva swallows, medication capsules, speaking, and drinking water, with average precision and recall of 90.17% and 88.9%, respectively. A total of 135 instances were classified from a total of 20 subjects. Conclusion Our experimental evaluations confirm the accuracy of the piezoelectric necklace for detecting medicine swallows and disambiguating them from related actions. Further studies in real-world conditions are necessary to evaluate the efficacy of the proposed scheme.

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Crossref · 10.1016/j.artmed.2016.03.004

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Authors
Kalantarian, H., Motamed, B., Alshurafa, N., & Sarrafzadeh, M.
Affiliations
  • University of California, Los Angeles (US)
  • Northwestern University (US)
Corresponding author
Kalantarian, Haik
Venue
Artificial Intelligence in Medicine
Publisher
Elsevier BV
Published
2016-05
Volume
69
Pages
43-52
ISSN
0933-3657 (ISSN-L)
OpenAlex
W2330005225
Cited by
86
References
52
Citations by year
2026: 3 · 2025: 8 · 2024: 7 · 2023: 14 · 2022: 11 · 2021: 12 · 2020: 8 · 2019: 7 · 2018: 6 · 2017: 9 · 2016: 1
FWCI
5.21
Type
journal article
Language
en
Open access
closed
Locations
  • Artificial Intelligence in Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Context-Aware Activity Recognition Systems
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
Keywords
medication adherence, wearable sensors, piezoelectric sensors, Bayesian networks, action classification, hospital readmission
MeSH terms
Wearable Electronic Devices, Administration, Oral, Bayes Theorem, Deglutition, Forecasting, Humans, Medication Adherence

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