Cited by 166Medication Adherence and ComplianceMobile Health and mHealth ApplicationsPharmacy and Medical Practices

Medication adherence: emerging use of technology

Open access
Granger, Bradi B, Bosworth, Hayden B·2011·Current Opinion in Cardiology

Abstract

PURPOSE OF REVIEW: Adherence to proven, effective medications remains low, resulting in high rates of clinical complications, hospital readmissions, and death. The use of technology to identify patients at risk and to target interventions for poor adherence has increased. This review focuses on research that tests these emerging technologies and evaluates the effect of technology-based adherence interventions on cardiovascular outcomes. RECENT FINDINGS: Recent studies have evaluated technology-based interventions to improve medication adherence by using pharmaceutical databases, tailoring educational information to individual patient needs, delivering technology-driven reminders to patients and providers, and integrating in-person interventions with electronic alerts. Cellular phone reminders and in-home electronic technology used to communicate reminder messages have shown mixed results. Only one study has shown improvement in both adherence and clinical outcome. Current trials suggest that increasing automated reminders will complement but not replace the benefits seen with in-person communication for medication taking. SUMMARY: Integration of in-person contacts with technology-driven medication adherence reminders, electronic medication reconciliation, and pharmaceutical databases may improve medication adherence and have a positive effect on cardiovascular clinical outcomes. Opportunities for providers to monitor the quality of care based on new adherence research are evolving and may be useful as standards for quality improvement emerge.

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Crossref · 10.1097/hco.0b013e328347c150

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99 of 99 references verified0 citation errors · 0 not checkable

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  • Poor adherence to prescribed medicines is considered a significant health challenge and one of the leading causes for emergency complications arising from issues related to heart disease, diabetes, hypertension and mental health.

    “Medication management for older adults remains an essential area of research, as poor adherence to prescribed medicines is considered to be a signifcant health challenge [15] and one of the leading causes for emergency complications arising from issues related to heart disease, diabetes, hypertension and mental health [4,15].”

    From A Collaborative Approach to Support Medication Management in Older Adults with Mild Cognitive Impairment Using Conversational Assistants (CAs) (2022) · cites this paper as [15]

    The Introduction calls poor medication adherence a major global public-health challenge and associates it with serious complications and increased hospitalization in cardiovascular disease, including hypertension. It does not establish that nonadherence is a leading cause of emergency complications, or make that claim for diabetes or mental-health conditions. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • The analysis of reminder use is based on a research methodology that relies on self-reported adherence as the primary factor for the validation of medication use.

    “the analysis of reminder use is based on a research methodology that relies on self-reported adherence as the primary factor for the validation of medication use [19-23].”

    From Voice Assistant Reminders and the Latency of Scheduled Medication Use in Older Adults With Pain: Descriptive Feasibility Study (2021) · cites this paper as [21]

    The 'Pharmaceutical database technologies and automated alerts' section discusses reminder studies using electronic monitoring and refill adherence, but does not say that self-reported adherence was their primary means of validating medication use. The only self-reported-adherence match is a title in the References; a search for adherence-measurement methods found no passage establishing the claimed methodology. Page numbers are unavailable in our copy. (LLM, conf=0.73)

    Experimental — accuracy not yet measured

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Cites

1 retracted

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Research works printed but not linked: 3

  1. [26]Bosworth HB Improving Patient Treatment Adherence: A Clinician Guidebook 2010 Springer New York
  2. [62]Inglis SC Clark RA Cleland JG Telemonitoring in patients with heart failure N Engl J Med 2011 364 11 1078 1079 author reply 1079-1080 21410377
  3. [69]Committee on Quality of Health Care in America IoM Crossing the Quality Chasm: A New Health System for the 21st Century 2001 National Academies Press Washington, DC

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Authors
Granger, B. B., & Bosworth, H. B.
Affiliations
Duke University (US)
Corresponding author
Granger, Bradi B
Venue
Current Opinion in Cardiology
Published
2011-07
Volume
26
Issue
4
Pages
279-287
ISSN
0268-4705 (ISSN-L)
OpenAlex
W1972147101
Cited by
165
References
98
Citations by year
2026: 4 · 2025: 5 · 2024: 4 · 2023: 11 · 2022: 17 · 2021: 16 · 2020: 8 · 2019: 9 · 2018: 12 · 2017: 19 · 2016: 11 · 2015: 18 · 2014: 9 · 2013: 14 · 2012: 8
FWCI
1.42
Type
journal article
Language
en
Open access
Locations
  • Current Opinion in Cardiology (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Center for Research Resources (UL1RR024128)
Topics
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
Keywords
medication adherence, technology-based interventions, medication reminders, pharmaceutical databases, personalized patient education, cardiovascular outcomes, hospital readmission, quality of care monitoring
MeSH terms
Cardiovascular Diseases, Humans, Self Care, Databases, Factual, Reminder Systems, Patient Satisfaction, Practice Guidelines as Topic, Electronic Mail, Cell Phone, Medication Adherence

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