Cited by 216Diabetes, Cardiovascular Risks, and LipoproteinsCardiovascular Health and Risk FactorsHealthcare Systems and Public Health

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Prevalence of the metabolic syndrome in patients with coronary heart disease, cerebrovascular disease, peripheral arterial disease or abdominal aortic aneurysm

Gorter, Petra M, Olijhoek, Jobien K, van der Graaf, Yolanda, Algra, Ale, Rabelink, Ton J, Visseren, Frank L.J·2004·Atherosclerosis

DOI 10.1016/j.atherosclerosis.2003.12.033

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Abstract

Metabolic syndrome patients are at increased risk for developing cardiovascular morbidity and mortality. The increasing prevalence of the metabolic syndrome in various asymptomatic populations has been well documented, however, limited information is available about the prevalence in manifest atherosclerotic vascular disease patients. The aim of this study is to determine the overall and gender-specific prevalence of the metabolic syndrome and its components in these patients. This cross-sectional survey of 1117 patients, aged 18-80 years, mean age 60+/-10 years, comprised patients with coronary heart disease (n=527), cerebrovascular disease (n=258), peripheral arterial disease (n=232) or abdominal aortic aneurysm (n=100). Metabolic syndrome was defined by Adult Treatment Panel III. The prevalence of the metabolic syndrome in the study population was 46%: 58% in PAD patients, 41% in CHD patients, 43% in CVD patients and 47% in AAA patients. Overall, women had a higher prevalence than men (56% versus 43%). Age did not influence the metabolic syndrome prevalence; crude odds ratios (crude OR) 1.00 (95% CI: 0.99-1.02). Our results demonstrate a high prevalence of the metabolic syndrome in patients with manifest atherosclerotic vascular disease. Screening for metabolic syndrome in patients with high risk for new vascular incidents may identify patients with even higher vascular risk and may direct anti-atherosclerotic treatment in order to prevent new vascular incidents in the same or another vascular bed.

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Authors: Gorter, P. M., Olijhoek, J. K., van der Graaf, Y., Algra, A., Rabelink, T. J., & Visseren, F. L. J.
Affiliations: University Medical Center Utrecht (NL)
Corresponding author: Olijhoek, Jobien K
ORCID: Algra, Ale
Rabelink, Ton J
Visseren, Frank L.J
Venue: Atherosclerosis
Publisher: Elsevier BV
Published: 2004-04
Volume: 173
Issue: 2
Pages: 361-367
ISSN: 0021-9150 (ISSN-L)
DOI: 10.1016/j.atherosclerosis.2003.12.033
OpenAlex: W2020922372
Cited by: 216
References: 18
Citations by year: 2026: 2 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 6 · 2021: 6 · 2020: 4 · 2019: 4 · 2018: 6 · 2017: 5 · 2016: 11 · 2015: 15 · 2014: 12 · 2013: 10 · 2012: 13
FWCI: 12.28
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Atherosclerosis (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
Keywords: metabolic syndrome, prevalence, coronary artery disease, cerebrovascular disease, peripheral arterial disease, abdominal aortic aneurysm, atherosclerosis, sex differences, metabolic syndrome screening, cardiovascular risk
MeSH terms: Adolescent, Adult, Aged, Aged, 80 and over, Arterial Occlusive Diseases, Cerebrovascular Disorders, Coronary Disease, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Netherlands, Cohort Studies, Comorbidity, Prevalence, Multivariate Analysis, Logistic Models, Survival Analysis, Peripheral Vascular Diseases, Aortic Aneurysm, Abdominal, Age Distribution, Sex Distribution, Risk Assessment, Metabolic Syndrome

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Prevalence of the metabolic syndrome in patients with coronary heart disease, cerebrovascular disease, peripheral arterial disease or abdominal aortic aneurysm

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