Cited by 136Congenital Heart Disease StudiesCardiac and Coronary Surgery TechniquesTransplantation: Methods and Outcomes

Variation in outcomes for risk-stratified pediatric cardiac surgical operations: An analysis of the STS congenital heart surgery database

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Jacobs, Jeffrey Phillip, O'Brien, Sean M., Pasquali, Sara K., Jacobs, Marshall Lewis, Lacour-Gayet, François G., Tchervenkov, Christo I., Austin, Erle H., Pizarro, Christian +7 more·2012·The Annals of Thoracic Surgery

Abstract

Background We evaluated outcomes for groups of risk-stratified operations in The Society of Thoracic Surgeons Congenital Heart Surgery Database to provide contemporary benchmarks and examine variation between centers.Methods Patients undergoing surgery from 2005 to 2009 were included. Centers with more than 10% missing data were excluded. Discharge mortality and postoperative length of stay (PLOS) among patients discharged alive were calculated for groups of risk-stratified operations using the five Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery Congenital Heart Surgery mortality categories (STAT Mortality Categories). Power for analyzing between-center differences in outcome was determined for each STAT Mortality Category. Variation was evaluated using funnel plots and Bayesian hierarchical modeling.Results In this analysis of risk-stratified operations, 58,506 index operations at 73 centers were included. Overall discharge mortality (interquartile range among programs with more than 10 cases) was as follows: STAT Category 1=0.55% (0% to 1.0%), STAT Category 2=1.7% (1.0% to 2.2%), STAT Category 3=2.6% (1.1% to 4.4%), STAT Category 4=8.0% (6.3% to 11.1%), and STAT Category 5=18.4% (13.9% to 27.9%). Funnel plots with 95% prediction limits revealed the number of centers characterized as outliers by STAT Mortality Categories was as follows: Category 1=3 (4.1%), Category 2=1 (1.4%), Category 3=7 (9.7%), Category 4=13 (17.8%), and Category 5=13 (18.6%). Between-center variation in PLOS was analyzed for all STAT Categories and was greatest for STAT Category 5 operations.Conclusions This analysis documents contemporary benchmarks for risk-stratified pediatric cardiac surgical operations grouped by STAT Mortality Categories and the range of outcomes among centers. Variation was greatest for the more complex operations. These data may aid in the design and planning of quality assessment and quality improvement initiatives.

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Crossref · 10.1016/j.athoracsur.2012.01.105

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  • In a multicenter study focusing exclusively on neonates, a VVR score ≥ 35 at 48 h post-surgery was more predictive of prolonged mechanical ventilation than VIS, the ventilation index (VI), or lactate levels.

    “In a multicenter study focusing exclusively on neonates, a VVR score ≥ 35 at 48 h post-surgery was more predictive of prolonged mechanical ventilation than VIS, the ventilation index (VI), or lactate levels [46].”

    From Trends and Challenges in Noninvasive Hemodynamic Monitoring of Neonates Following Cardiac Surgery: A Narrative Review (2025) · cites this paper as [46]

    The Material and Methods > Analytic Methods passage identifies discharge mortality and postoperative length of stay as the study’s outcomes, not prolonged mechanical ventilation. Searches for VVR ≥35 at 48 hours, neonates, VIS, ventilation index, and lactate found no passage addressing the claimed prediction comparison. The cited paper’s copy therefore does not verify this claim. (LLM, conf=0.76)

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Authors
Jacobs, J. P., O'Brien, S. M., Pasquali, S. K., Jacobs, M. L., Lacour-Gayet, F. G., Tchervenkov, C. I., Austin, E. H., Pizarro, C., Pourmoghadam, K. K., Scholl, F. G., Welke, K. F., Gaynor, J. W., Clarke, D. R., Mayer, J. E., & Mavroudis, C.
Affiliations
  • University of South Florida (US)
  • Duke University (US)
  • Cleveland Clinic (US)
  • Montreal Children's Hospital (CA)
  • University of Louisville (US)
  • Alfred I. duPont Hospital for Children (US)
  • University of Oklahoma Health Sciences Center (US)
  • Joe DiMaggio Children's Hospital (US)
  • Seattle Children's Hospital (US)
  • Children's Hospital of Philadelphia (US)
  • University of Colorado Anschutz (US)
  • Boston Children's Hospital (US)
  • AdventHealth for Children (US)
Corresponding author
Jacobs, Jeffrey Phillip
Venue
The Annals of Thoracic Surgery
Publisher
Elsevier BV
Published
2012-08
Volume
94
Issue
2
Pages
564-572
ISSN
0003-4975 (ISSN-L)
OpenAlex
W2097421050
Cited by
136
References
14
Citations by year
2026: 5 · 2025: 8 · 2024: 6 · 2023: 14 · 2022: 4 · 2021: 13 · 2020: 7 · 2019: 7 · 2018: 7 · 2017: 9 · 2016: 18 · 2015: 5 · 2014: 18 · 2013: 12 · 2012: 2
FWCI
8.86
Type
journal article
Language
en
Open access
Locations
  • The Annals of Thoracic Surgery (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Heart, Lung, and Blood Institute (K08HL103631)
Topics
  • Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
  • Health Sciences › Medicine › Surgery › Cardiac and Coronary Surgery Techniques
  • Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
Keywords
pediatric cardiac surgery, congenital heart surgery, risk stratification, surgical outcomes, discharge mortality, postoperative hospital stay, quality standards, Society of Thoracic Surgeons Congenital Heart Surgery Database, quality improvement
MeSH terms
Adolescent, Child, Female, Heart Defects, Congenital, Heart Diseases, Cardiac Surgical Procedures, Humans, Male, Databases, Factual, Treatment Outcome, Risk Assessment, Benchmarking

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