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Impact of O-GlcNAc on cardioprotection by remote ischaemic preconditioning in non-diabetic and diabetic patients

Jensen, R. V., Zachara, N. E., Nielsen, P. H., Kimose, H., Kristiansen, S. B., & Bøtker, H. E. (2012) · Cardiovascular Research · doi:10.1093/cvr/cvs337 · Cited by 100 · see citing works

The mitochondrial KATP channel—Fact or fiction?

Garlid, K., & Halestrap, A. P. (2012) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2011.12.011 · Cited by 85 · see citing works

Physiological consequences of complex II inhibition for aging, disease, and the mKATP channel

Wojtovich, A. P., Smith, C. O., Haynes, C. M., Nehrke, K. W., & Brookes, P. S. (2013) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2012.12.007 · Cited by 83 · see citing works

New and revisited approaches to preserving the reperfused myocardium

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Mammalian ACSF3 Protein Is a Malonyl-CoA Synthetase That Supplies the Chain Extender Units for Mitochondrial Fatty Acid Synthesis

Witkowski, A., Thweatt, J. L., & Smith, S. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.291591 · Cited by 80 · see citing works

Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain complexes I and III

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Novel channels of the inner mitochondrial membrane

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Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex II

Kôrge, P., John, S., Calmettes, G., & Weiss, J. N. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.768325 · Cited by 63 · see citing works

A spectrophotometric coupled enzyme assay to measure the activity of succinate dehydrogenase

Jones, A. J. Y., & Hirst, J. (2013) · Analytical Biochemistry · doi:10.1016/j.ab.2013.07.018 · Cited by 62 · see citing works

Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart

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A Novel Mitochondrial KATPChannel Assay

Wojtovich, A. P., Williams, D. M., Karcz, M., Lopes, C. M. B., Gray, D. A., Nehrke, K. W., & Brookes, P. S. (2010) · Circulation Research · doi:10.1161/circresaha.109.215400 · Cited by 55 · see citing works

Predicting and Defining Steroid Resistance in Pediatric Nephrotic Syndrome Using Plasma Proteomics

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Mitochondrial ion transport pathways: Role in metabolic diseases

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Synthesis and Antineoplastic Evaluation of Mitochondrial Complex II (Succinate Dehydrogenase) Inhibitors Derived from Atpenin A5

Wang, H., Huwaimel, B., Verma, K., Miller, J. E., Germain, T., Kinarivala, N., Pappas, D., Brookes, P. S., & Trippier, P. C. (2017) · ChemMedChem · doi:10.1002/cmdc.201700196 · Cited by 52 · see citing works

Mitochondrial function and Aβ in Alzheimer's disease postmortem brain

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Krebs cycle metabolites and preferential succinate oxidation following neonatal hypoxic-ischemic brain injury in mice

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Aging-related compensated hypogonadism: Role of metabolomic analysis in physiopathological and therapeutic evaluation

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Pre‐ischaemic mitochondrial substrate constraint by inhibition of malate‐aspartate shuttle preserves mitochondrial function after ischaemia–reperfusion

Jespersen, N. R., Yokota, T., Støttrup, N. B., Bergdahl, A., Pælestik, K., Povlsen, J. A., Dela, F., & Bøtker, H. E. (2017) · The Journal of Physiology · doi:10.1113/jp273408 · Cited by 47 · see citing works

Direct Activation of β-Cell KATP Channels with a Novel Xanthine Derivative

Raphemot, R., Swale, D. R., Dadi, P., Jacobson, D., Cooper, P., Wojtovich, A. P., Banerjee, S., Nichols, C., & Denton, J. (2014) · Molecular Pharmacology · doi:10.1124/mol.114.091884 · Cited by 40 · see citing works

Mitochondrial Reactive Oxygen Species Generated at the Complex-II Matrix or Intermembrane Space Microdomain Have Distinct Effects on Redox Signaling and Stress Sensitivity in Caenorhabditis elegans

Trewin, A. J., Bahr, L. L., Almast, A., Berry, B. J., Wei, A. Y., Foster, T. H., & Wojtovich, A. P. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2018.7681 · Cited by 43 · see citing works

Bioenergetic defect associated with mK ATP channel opening in a mouse model carrying a mitofusin 2 mutation

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Predicting and Defining Steroid Resistance in Pediatric Nephrotic Syndrome Using Plasma Metabolomics

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Acid enhancement of ROS generation by complex-I reverse electron transport is balanced by acid inhibition of complex-II: Relevance for tissue reperfusion injury

Milliken, A. S., Kulkarni, C. A., & Brookes, P. S. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101733 · Cited by 40 · see citing works

Signaling pathways targeting mitochondrial potassium channels

Rotko, D., Kunz, W. S., Szewczyk, A. M., & Kulawiak, B. (2020) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2020.105792 · Cited by 39 · see citing works

The Slo(w) path to identifying the mitochondrial channels responsible for ischemic protection

Smith, C. O., Nehrke, K. W., & Brookes, P. S. (2017) · Biochemical Journal · doi:10.1042/bcj20160623 · Cited by 37 · see citing works

Ischemic Preconditioning Decreases Mitochondrial Proton Leak and Reactive Oxygen Species Production in the Postischemic Heart

Quarrie, R., Cramer, B., Lee, D. S., Steinbaugh, G. E., Erdahl, W. L., Pfeiffer, D. R., Zweier, J. L., & Crestanello, J. A. (2010) · Journal of Surgical Research · doi:10.1016/j.jss.2010.09.018 · Cited by 37 · see citing works

Regulated production of free radicals by the mitochondrial electron transport chain: Cardiac ischemic preconditioning☆

Matsuzaki, S., Szweda, P. A., Szweda, L. I., & Humphries, K. M. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.05.008 · Cited by 35 · see citing works

Fatty acid nitroalkenes induce resistance to ischemic cardiac injury by modulating mitochondrial respiration at complex II

Koenitzer, J. R., Bonacci, G., Woodcock, S. R., Chen, C.-S., Cantú‐Medellín, N., Kelley, E. E., & Schopfer, F. J. (2015) · Redox Biology · doi:10.1016/j.redox.2015.11.002 · Cited by 35 · see citing works

Inhibition of succinate-linked respiration and complex II activity by hydrogen peroxide

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Chromophore-Assisted Light Inactivation of Mitochondrial Electron Transport Chain Complex II in Caenorhabditis elegans

Wojtovich, A. P., Wei, A. Y., Sherman, T. A., Foster, T. H., & Nehrke, K. W. (2016) · Scientific Reports · doi:10.1038/srep29695 · Cited by 34 · see citing works

Preservation of the in vivo state of mitochondrial network for ex vivo physiological study of mitochondria

Kondrashova, M. N., Zakharchenko, M. V., & Khunderyakova, N. (2009) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2009.04.020 · Cited by 33 · see citing works

Ischemic and hypoxic preconditioning protect cardiac muscles via intracellular ROS signaling

Zuo, L., Roberts, W. J., Tolomello, R. C., & Goins, A. T. (2012) · Frontiers in Biology · doi:10.1007/s11515-012-1225-z · Cited by 33 · see citing works

Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex III

Kôrge, P., Calmettes, G., John, S., & Weiss, J. N. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.768317 · Cited by 32 · see citing works

The C. elegans mitochondrial K+ATP channel: A potential target for preconditioning

Wojtovich, A. P., Burwell, L. S., Sherman, T. A., Nehrke, K. W., & Brookes, P. S. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.09.043 · Cited by 31 · see citing works

Mechanisms of the Beneficial Actions of Ischemic Preconditioning on Subcellular Remodeling in Ischemic-Reperfused Heart

Muller, B. A. L., & Dhalla, N. S. (2010) · Current Cardiology Reviews · doi:10.2174/157340310793566118 · Cited by 29 · see citing works

Mitochondrial K+ Transport: Modulation and Functional Consequences

Pereira, O. R., & Kowaltowski, A. J. (2021) · Molecules · doi:10.3390/molecules26102935 · Cited by 26 · see citing works

Anti-aging effects of chlorpropamide depend on mitochondrial complex-II and the production of mitochondrial reactive oxygen species

Mao, Z., Liu, W., Huang, Y., Sun, T., Bao, K., Feng, J., Moskalev, A., Hu, Z., & Li, J. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.08.007 · Cited by 26 · see citing works

Mitochondrial Inhibition in Rat Retinal Cell Cultures as a Model of Metabolic Compromise: Mechanisms of Injury and Neuroprotection

Wood, J. P. M., Mammone, T., Chidlow, G., Greenwell, T., & Casson, R. J. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.11-9171 · Cited by 25 · see citing works

Ischemic preconditioning preserves mitochondrial membrane potential and limits reactive oxygen species production

Quarrie, R., Lee, D. S., Steinbaugh, G. E., Cramer, B., Erdahl, W. L., Pfeiffer, D. R., Zweier, J. L., & Crestanello, J. A. (2012) · Journal of Surgical Research · doi:10.1016/j.jss.2012.05.090 · Cited by 25 · see citing works

Respiratory complex II in mitochondrial dysfunction-mediated cytotoxicity: Insight from cadmium

Belyaeva, E. A. (2018) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2018.06.009 · Cited by 24 · see citing works

Mitochondrial plasticity in the cerebellum of two anoxia-tolerant sharks: contrasting responses to anoxia/reoxygenation

Devaux, J. B. L., Hickey, A. J., & Renshaw, G. M. C. (2019) · Journal of Experimental Biology · doi:10.1242/jeb.191353 · Cited by 24 · see citing works

Modification of Ischemia/Reperfusion-Induced Alterations in Subcellular Organelles by Ischemic Preconditioning

Tappia, P. S., Shah, A. K., Ramjiawan, B., & Dhalla, N. S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073425 · Cited by 23 · see citing works

The emerging role of the mitochondrial fatty-acid synthase (mtFASII) in the regulation of energy metabolism

Wehbe, Z., Behringer, S., Alatibi, K. I., Watkins, D., Rosenblatt, D. S., Spiekerkoetter, U., & Tucci, S. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2019.07.012 · Cited by 22 · see citing works

Mitochondrial ATP‐sensitive potassium channel activity and hypoxic preconditioning are independent of an inwardly rectifying potassium channel subunit in Caenorhabditis elegans

Wojtovich, A. P., DiStefano, P. S., Sherman, T., Brookes, P. S., & Nehrke, K. W. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.01.021 · Cited by 22 · see citing works

Optical Control of Cellular ATP Levels with a Photocaged Adenylate Kinase

Zhou, W., Hankinson, C. P., & Deiters, A. (2020) · ChemBioChem · doi:10.1002/cbic.201900757 · Cited by 22 · see citing works

Inhibition of Succinate Dehydrogenase by Diazoxide Is Independent of the ATP-Sensitive Potassium Channel Subunit Sulfonylurea Type 1 Receptor

Anastacio, M. M., Kanter, E. M., Keith, A. D., Schuessler, R. B., Nichols, C. G., & Lawton, J. S. (2013) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2013.01.048 · Cited by 22 · see citing works

Self‐photocatalyzed Homolytic Dehalogenative Alkylation/Cyclization of Unactivated Alkenes Based on the Quinazolinone Skeleton via Energy Transfer

Sun, B. X., Tang, X., Shi, R., Yan, Z., Li, B., Tang, C., Jin, C., Wu, C., & Shen, R. (2021) · Asian Journal of Organic Chemistry · doi:10.1002/ajoc.202100606 · Cited by 21 · see citing works

Inhibition of Snowshoe Hare Succinate Dehydrogenase Activity as a Mechanism of Deterrence for Papyriferic Acid in Birch

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Cardioprotective Mechanism of Diazoxide Involves the Inhibition of Succinate Dehydrogenase

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Routes for Potassium Ions across Mitochondrial Membranes: A Biophysical Point of View with Special Focus on the ATP-Sensitive K+ Channel

Kravenska, Y., Checchetto, V., & Szabó, I. (2021) · Biomolecules · doi:10.3390/biom11081172 · Cited by 21 · see citing works

Mitochondrialne kanały potasowe: podsumowanie

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Middle age aggravates myocardial ischemia through surprising upholding of complex II activity, oxidative stress, and reduced coronary perfusion

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The mitochondrial complex II and ATP-sensitive potassium channel interaction: quantitation of the channel in heart mitochondria.

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Modulation of mitochondrial site-specific hydrogen peroxide efflux by exogenous stressors

Okoye, C. N., Stevens, D., & Kamunde, C. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.12.234 · Cited by 18 · see citing works

Inhibition of lipolysis: A novel explanation for the hypothermic actions of acetaminophen in non-febrile rodents

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Traditional and novel tools to probe the mitochondrial metabolism in health and disease

Zhang, Y., & Avalos‬, J. L. (2017) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1373 · Cited by 17 · see citing works

P o 2 cycling protects diaphragm function during reoxygenation via ROS, Akt, ERK, and mitochondrial channels

Zuo, L., Pannell, B. K., Re, A. T., Best, T. M., & Wagner, P. D. (2015) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00174.2015 · Cited by 16 · see citing works

The 40-Hz White Light-Emitting Diode (LED) Improves the Structure–Function of the Brain Mitochondrial KATP Channel and Respiratory Chain Activities in Amyloid Beta Toxicity

Nazari, M., Vajed-Samiei, T., Torabi, N., Fahanik‐Babaei, J., Saghiri, R., Khodagholi, F., & Eliassi, A. (2022) · Molecular Neurobiology · doi:10.1007/s12035-021-02681-7 · Cited by 15 · see citing works

Alternative Targets for Modulators of Mitochondrial Potassium Channels

Wrzosek, A., Gałecka, S., Żochowska, M., Olszewska, A., & Kulawiak, B. (2022) · Molecules · doi:10.3390/molecules27010299 · Cited by 15 · see citing works

Mitochondrial cardiovascular diseases: molecular mechanisms, multi-omics exploration and therapeutic strategies

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Ion channel-mediated mitochondrial volume regulation and its relationship with mitochondrial dynamics

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The effect of atp-dependent potassium uptake on mitochondrial functions under acute hypoxia

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Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity**

Huwaimel, B., Bhakta, M., Kulkarni, C. A., Milliken, A. S., Wang, F., Peng, A., Brookes, P. S., & Trippier, P. C. (2020) · ChemMedChem · doi:10.1002/cmdc.202000729 · Cited by 13 · see citing works

Targeting the Host Mitochondria as a Novel Human Cytomegalovirus Antiviral Strategy

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Plasma metabolomics pilot study suggests age and sex-based differences in the metabolic response to traumatic injury

Lusczek, E. R., Myers, C., Popovsky, K., Mulier, K. E., Beilman, G. J., & Sawyer, R. G. (2018) · Injury · doi:10.1016/j.injury.2018.09.033 · Cited by 13 · see citing works

Metabolic Regulation of Copper Toxicity during Marine Mussel Embryogenesis

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Altered mitochondrial functioning induced by preoperative fasting may underlie protection against renal ischemia/reperfusion injury

Verweij, M., Sluiter, W. J., van den Engel, S., Jansen, E. H. J. M., IJzermans, J. N. M., & de Bruin, R. W. F. (2012) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24360 · Cited by 11 · see citing works

Cardioprotective mechanisms of mitochondria-targeted S-nitrosating agent and adenosine triphosphate-sensitive potassium channel opener are mutually exclusive

Ahmad, T., Wang, J., Velez, A. K., Suarez‐Pierre, A., Clement, K. C., Dong, J., Sebestyen, K., Canner, J. K., Murphy, M. P., & Lawton, J. S. (2021) · JTCVS Open · doi:10.1016/j.xjon.2021.07.036 · Cited by 10 · see citing works

2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver

Kosharskyy, B., Vydyanathan, A., Zhang, L., Shaparin, N., Geohagen, B. C., Bivin, W. W., Liu, Q., Gavin, T., & LoPachin, R. M. (2015) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.114.221622 · Cited by 10 · see citing works

Mitochondria from rat uterine smooth muscle possess ATP-sensitive potassium channel

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Connexin 43 modulates reverse electron transfer in cardiac mitochondria from inducible knock-out Cx43Cre−ER(T)/fl mice by altering the coenzyme Q pool

Consegal, M., Miró‐Casas, E., Barba, I., Ruiz‐Meana, M., Inserte, J., Benito, B., Rodrı́guez, C., Ganse, F. G., Rubio-Unguetti, L., Llorens-Cebrià, C., et al. (2024) · Basic Research in Cardiology · doi:10.1007/s00395-024-01052-2 · Cited by 8 · see citing works

Copper modulates heart mitochondrial H2O2 emission differently during fatty acid and pyruvate oxidation

Isei, M. O., Stevens, D., & Kamunde, C. (2022) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2022.109267 · Cited by 7 · see citing works

The protection effects of (1E,6E)-1,7-diphenylhepta-1,6-diene-3,5-dione, a curcumin analogue, against operative liver injury in rats

Chi, X., Yu, D., Li, P., Lu, Q., Jiang, W., & Hao, K. (2017) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2016.12.042 · Cited by 8 · see citing works

Effect of hypoxen on bioenergetic processes in mitochondria and activity of ATP-sensitive potassium channel

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Deficiency of Mitochondrial Functions and Peroxidation of Frontoparietal Cortex Enhance Isoflurane Sensitivity in Aging Mice

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Malonate induces the browning of white adipose tissue in high-fat diet induced obesity model

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Intracellular calcium, preconditioning and regulation of cellular respiration in heart

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Respiratory uncoupling by increased H+ or K+ flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition

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Anoxia-reoxygenation alters H2O2 efflux and sensitivity of redox centers to copper in heart mitochondria

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Effect of diazoxide on AS-30D rat ascites hepatoma cells treated by Cd2+

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A robust method for assessing mitochondrial function in healthy and diseased frozen cardiac tissue

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