Peroxisomal β-oxidation—A metabolic pathway with multiple functions

Biochemistry of mammalian peroxisomes revisited

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β-Oxidation of fatty acids in mitochondria, peroxisomes, and bacteria: A century of continued progress

Kunau, W. (1995) · Progress in Lipid Research · doi:10.1016/0163-7827(95)00011-9 · Cited by 510

The biochemistry of peroxisomal β-oxidation in the yeast Saccharomyces cerevisiae

Hiltunen, J. K., Mursula, A. M., Rottensteiner, H., Wierenga, R. K., Kastaniotis, A. J., & Gurvitz, A. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00017-2 · Cited by 348

Role of β-Oxidation in Jasmonate Biosynthesis and Systemic Wound Signaling in Tomato

Li, C., Schilmiller, A. L., Liu, G., Lee, G. I., Jayanty, S. S., Sageman, C., Vrebalov, J., Giovannoni, J. J., Yagi, K., Kobayashi, Y., et al. (2005) · The Plant Cell · doi:10.1105/tpc.104.029108 · Cited by 304

Genetic Analysis of Indole-3-butyric Acid Responses in Arabidopsis thaliana Reveals Four Mutant Classes

Zolman, B. K., Yoder, A., & Bartel, B. (2000) · Genetics · doi:10.1093/genetics/156.3.1323 · Cited by 290

The role Acyl-CoA thioesterases play in mediating intracellular lipid metabolism

Hunt, M. C., & Alexson, S. E. H. (2002) · Progress in Lipid Research · doi:10.1016/s0163-7827(01)00017-0 · Cited by 278

2,4-Dichlorophenoxybutyric Acid–Resistant Mutants of Arabidopsis Have Defects in Glyoxysomal Fatty Acid β-Oxidation

Hayashi, M., Toriyama, K., Kondo, M., & Nishimura, M. (1998) · The Plant Cell · doi:10.1105/tpc.10.2.183 · Cited by 274

Chewing the fat: β-oxidation in signalling and development

Baker, A., Graham, I. A., Holdsworth, M., Smith, S. M., & Theodoulou, F. L. (2006) · Trends in Plant Science · doi:10.1016/j.tplants.2006.01.005 · Cited by 271

Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene

Fan, C.-Y., Pan, J., Chu, R., Lee, D., Kluckman, K. D., Usuda, N., Singh, I., Yeldandi, A. V., Rao, M. S., Maeda, N., et al. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.40.24698 · Cited by 268

Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy

Ferdinandusse, S., Denis, S., Clayton, P. T., Graham, A., Rees, J. E., Allen, J. T., McLean, B. N., Brown, A. Y., Vreken, P., Waterham, H. R., et al. (2000) · Nature Genetics · doi:10.1038/72861 · Cited by 262

Requirement for 3‐ketoacyl‐CoA thiolase‐2 in peroxisome development, fatty acid β‐oxidation and breakdown of triacylglycerol in lipid bodies of Arabidopsis seedlings

Germain, V., Rylott, E. L., Larson, T. R., Sherson, S. M., Bechtold, N., Carde, J., Bryce, J. H., Graham, I. A., & Smith, S. M. (2001) · The Plant Journal · doi:10.1046/j.1365-313x.2001.01095.x · Cited by 249

Gene structure, intracellular localization, and functional roles of sterol carrier protein-2

Gallegos, A. M., Atshaves, B. P., Storey, S. M., Starodub, O., Petrescu, A. D., Huang, H., McIntosh, A. L., Martin, G. G., Chao, H., Kier, A. B., et al. (2001) · Progress in Lipid Research · doi:10.1016/s0163-7827(01)00015-7 · Cited by 231

Peroxisomal multifunctional beta-oxidation protein of Saccharomyces cerevisiae. Molecular analysis of the fox2 gene and gene product.

Hiltunen, J. K., Wenzel, B., Beyer, A., Erdmann, R., Fosså, A., & Kunau, W. H. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50476-8 · Cited by 196

Structure and function of human 17β-hydroxysteroid dehydrogenases

Lukacik, P., Kavanagh, K. L., & Oppermann, U. C. T. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2005.12.007 · Cited by 195

Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy

Ferdinandusse, S., Denis, S., Clayton, P. T., Graham, A., Rees, J. E., Allen, J. T., McLean, B. N., Brown, A. Y., Vreken, P., Waterham, H. R., et al. (2001) · Biochemical Society Transactions · doi:10.1042/bst029a029c · Cited by 192

Peroxisomal βoxidation system of rat liver. Copurification of enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase

Osumi, T., & Hashimoto, T. (1979) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(79)90669-7 · Cited by 182

Peroxisomal bifunctional protein from rat liver is a trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities.

Palosaari, P. M., & Hiltunen, J. K. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39819-9 · Cited by 181

Sucrose rescues seedling establishment but not germination of Arabidopsis mutants disrupted in peroxisomal fatty acid catabolism

Pinfield‐Wells, H., Rylott, E. L., Gilday, A. D., Graham, S., Job, K., Larson, T. R., & Graham, I. A. (2005) · The Plant Journal · doi:10.1111/j.1365-313x.2005.02498.x · Cited by 178

A Defect in b-Oxidation Causes Abnormal Inflorescence Development in Arabidopsis

Richmond, T., & Bleecker, A. B. (1999) · The Plant Cell · doi:10.2307/3871086 · Cited by 171

The thiolase superfamily: condensing enzymes with diverse reaction specificities

Haapalainen, A. M., Meriläinen, G., & Wierenga, R. K. (2006) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.11.011 · Cited by 167

Identification of the peroxisomal β-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids

Ferdinandusse, S., Denis, S. W., van Roermund, C. W. T., Wanders, R. J. A., & Dacremont, G. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m300512-jlr200 · Cited by 150

Properties of Mitochondrial and Peroxisomal Enoyl-CoA Hydratases from Rat Liver1

Furuta, S., Miyazawa, S., Osumi, T., Hashimoto, T., & Ui, N. (1980) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a133057 · Cited by 150

Peroxisomal β‐oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: isocitrate dehydrogenase provides NADPH for reduction of double bonds at even positions

van Roermund, C. W. T., Hettema, E. H., Kal, A. J., van den Berg, M., Tabak, H. F., & Wanders, R. J. A. (1998) · The EMBO Journal · doi:10.1093/emboj/17.3.677 · Cited by 148

Gene-Specific Involvement of β-Oxidation in Wound-Activated Responses in Arabidopsis

Castillo, M. C., Martínez, C., Buchala, A. J., Métraux, J., & León, J. (2004) · PLANT PHYSIOLOGY · doi:10.1104/pp.104.039925 · Cited by 148

Mutations in the gene encoding peroxisomal sterol carrier protein X (SCPx) cause leukencephalopathy with dystonia and motor neuropathy

Ferdinandusse, S., Kostopoulos, P., Denis, S., Rusch, H., Overmars, H., Dillmann, U., Reith, W., Haas, D., Wanders, R. J. A., Duran, M., et al. (2006) · The American Journal of Human Genetics · doi:10.1086/503921 · Cited by 145

Quantitative Determination of Expression of the Prostate Cancer Protein α-Methylacyl-CoA Racemase Using Automated Quantitative Analysis (AQUA)

Rubin, M. A., Zerkowski, M. P., Camp, R. L., Kuefer, R., Hofer, M. D., Chinnaiyan, A. M., & Rimm, D. L. (2004) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63171-9 · Cited by 145

Degradation of Unsaturated Fatty Acids. Identification of Intermediates in the Degradation of cis-4-Decenoyl-CoA by Extracts of Beef-Liver Mitochondria

Kunau, W., & DOMMES, P. (1978) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1978.tb12707.x · Cited by 138

β-Oxidation – strategies for the metabolism of a wide variety of acyl-CoA esters

Hiltunen, J. K., & Qin, Y. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(00)00013-5 · Cited by 136

beta-Oxidation of polyunsaturated fatty acids by rat liver peroxisomes. A role for 2,4-dienoyl-coenzyme A reductase in peroxisomal beta-oxidation.

Hiltunen, J. K., Kärki, T., Hassinen, I. E., & Osmundsen, H. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66592-5 · Cited by 133

Increased Flow of Fatty Acids toward β-Oxidation in Developing Seeds of Arabidopsis Deficient in Diacylglycerol Acyltransferase Activity or Synthesizing Medium-Chain-Length Fatty Acids

Poirier, Y., Ventre, G., & Caldelari, D. (1999) · PLANT PHYSIOLOGY · doi:10.1104/pp.121.4.1359 · Cited by 120

Porcine 80-kDa protein reveals intrinsic 17β-hydroxysteroid dehydrogenase, fatty acyl-CoA-hydratase/dehydrogenase, and sterol transfer activities

Leenders, F., Tesdorpf, J. G., Markus, M., Engel, T., Seedorf, U., & Adamski, J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.10.5438 · Cited by 116

A Novel Acyl-CoA Oxidase That Can Oxidize Short-chain Acyl-CoA in Plant Peroxisomes

Hayashi, H., Bellis, L. D., Ciurli, A., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.18.12715 · Cited by 115

Purification and properties of an α‐methylacyl‐CoA racemase from rat liver

Schmitz, W., Fingerhut, R., & Conzelmann, E. (1994) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1994.tb18870.x · Cited by 115

Structural basis for channelling mechanism of a fatty acid β‐oxidation multienzyme complex

Ishikawa, M., Tsuchiya, D., Oyama, T., Tsunaka, Y., & Morikawa, K. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600298 · Cited by 114

Discovery and Clinical Application of a Novel Prostate Cancer Marker

Jiang, Z., Woda, B. A., Wu, C., & Yang, X. J. (2004) · American Journal of Clinical Pathology · doi:10.1309/ejuyuqpex1mg68mk · Cited by 112

Peroxisomal Straight-chain Acyl-CoA Oxidase and D-bifunctional Protein Are Essential for the Retroconversion Step in Docosahexaenoic Acid Synthesis

Su, H., Moser, A. B., Moser, H. W., & Watkins, P. A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106326200 · Cited by 111

Peroxisome Proliferator–induced Pleiotropic Responses: Pursuit of a Phenomenona

Reddy, J. K., & Chu, R. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb18616.x · Cited by 110

The Arabidopsis thaliana multifunctional protein gene (MFP2) of peroxisomal β‐oxidation is essential for seedling establishment

Rylott, E. L., Eastmond, P. J., Gilday, A. D., Slocombe, S. P., Larson, T. R., Baker, A., & Graham, I. A. (2006) · The Plant Journal · doi:10.1111/j.1365-313x.2005.02650.x · Cited by 110

Sterol carrier protein-2: structure reveals function

Stolowich, N. J., Petrescu, A. D., Huang, H., Martin, G. G., Scott, A. I., & Schroeder, F. (2002) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-002-8416-8 · Cited by 107

Arabidopsis Mutants in Short- and Medium-chain Acyl-CoA Oxidase Activities Accumulate Acyl-CoAs and Reveal That Fatty Acid β-Oxidation Is Essential for Embryo Development

Rylott, E. L., Rogers, C. A., Gilday, A. D., Edgell, T., Larson, T. R., & Graham, I. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300826200 · Cited by 104

The Identification of a Succinyl-CoA Thioesterase Suggests a Novel Pathway for Succinate Production in Peroxisomes

Westin, M. A. K., Hunt, M. C., & Alexson, S. E. H. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508479200 · Cited by 99

Fusion and Fission

Finger, F. P., & White, J. G. (2002) · Cell · doi:10.1016/s0092-8674(02)00668-2 · Cited by 95

Absence of Spontaneous Peroxisome Proliferation in Enoyl-CoA Hydratase/l-3-Hydroxyacyl-CoA Dehydrogenase-deficient Mouse Liver

Qi, C., Zhu, Y., Pan, J., Usuda, N., Maeda, N., Yeldandi, A. V., Rao, M. S., Hashimoto, T., & Reddy, J. K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.22.15775 · Cited by 92

NADPH-dependent beta-oxidation of unsaturated fatty acids with double bonds extending from odd-numbered carbon atoms.

Smeland, T. E., Nada, M. A. R., Cuebas, D. A., & Schulz, H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.15.6673 · Cited by 91

Peroxisomal multifunctional protein-2: The enzyme, the patients and the knockout mouse model.

Huyghe, S., Mannaerts, G. P., Baes, M., & Van Veldhoven, P. P. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2006.04.006 · Cited by 91

The Saccharomyces cerevisiae Peroxisomal 2,4-Dienoyl-CoA Reductase Is Encoded by the Oleate-inducible GeneSPS19

Gurvitz, A., Rottensteiner, H., Kilpeläinen, S. H., Hartig, A., Hiltunen, J. K., Binder, M., Dawes, I. W., & Hamilton, B. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.35.22140 · Cited by 89

Identification of Peroxisomal Acyl-CoA Thioesterases in Yeast and Humans

Jones, J. M., Nau, K., Geraghty, M. T., Erdmann, R., & Gould, S. J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.14.9216 · Cited by 87

Functions and Organization of Peroxisomal β‐Oxidation

Mannaerts, G. P., & Veldhoven, P. P. V. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb18611.x · Cited by 85

A mouse model for α-methylacyl-CoA racemase deficiency: adjustment of bile acid synthesis and intolerance to dietary methyl-branched lipids

Savolainen, K., Kotti, T. J., Schmitz, W., Savolainen, T. I., Sormunen, R. T., Ilves, M., Vainio, S. J., Conzelmann, E., & Hiltunen, J. K. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh107 · Cited by 83

Crystal Structure of the (R)-Specific Enoyl-CoA Hydratase from Aeromonas caviae Involved in Polyhydroxyalkanoate Biosynthesis

Hisano, T., Tsuge, T., Fukui, T., Iwata, T., Miki, K., & Doi, Y. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205484200 · Cited by 83

Peroxisomal β-Oxidation Enzymes

Hashimoto, T. (1999) · Neurochemical Research · doi:10.1023/a:1022540030918 · Cited by 79

The crystal structure of dienoyl-CoA isomerase at 1.5 å resolution reveals the importance of aspartate and glutamate sidechains for catalysis

Modis, Y., Filppula, S. A., Novikov, D. K., Norledge, B. V., Hiltunen, J. K., & Wierenga, R. K. (1998) · Structure · doi:10.1016/s0969-2126(98)00098-7 · Cited by 78

Peroxisomal β‐oxidation of 2‐methyl‐branched acyl‐CoA esters stereospecific recognition of the 2S‐methyl compounds by trihydroxycoprostanoyl‐CoA oxidase and pristanoyl‐CoA oxidase

Veldhoven, P. P. V., Croes, K., Asselberghs, S., Herdewijn, P. A., & Mannaerts, G. P. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00508-x · Cited by 75

Crystal structure of the liganded SCP-2-like domain of human peroxisomal multifunctional enzyme type 2 at 1.75 Å resolution 1 1Edited by R. Huber

Haapalainen, A. M., van Aalten, D. M. F., Meriläinen, G., Jalonen, J. E., Pirilä, P., Wierenga, R. K., Hiltunen, J. K., & Glumoff, T. (2001) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.5084 · Cited by 74

A Two-domain Structure of One Subunit Explains Unique Features of Eukaryotic Hydratase 2

Koski, M. K., Haapalainen, A. M., Hiltunen, J. K., & Glumoff, T. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400293200 · Cited by 68

Polyhydroxyalkanoate synthesis in transgenic plants as a new tool to study carbon flow through β‐oxidation

Mittendorf, V., Bongcam, V., Petrolati, L. A., Coullerez, G., Martini, N., & Poirier, Y. (1999) · The Plant Journal · doi:10.1046/j.1365-313x.1999.00572.x · Cited by 66

Peroxisomal Δ3-cis-Δ2-trans-Enoyl-CoA Isomerase Encoded by ECI1 Is Required for Growth of the Yeast Saccharomyces cerevisiae on Unsaturated Fatty Acids

Gurvitz, A., Mursula, A. M., Firzinger, A., Hamilton, B., Kilpeläinen, S. H., Hartig, A., Ruis, H., Hiltunen, J. K., & Rottensteiner, H. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.47.31366 · Cited by 65

Cloning, sequencing, and characterization of five genes coding for Acyl-CoA oxidase isozymes in the yeastYarrowia lipolytica

Wang, H., Dall, M. L., Waché, Y., Laroche, C., Belin, J., & Nicaud, J. (1999) · Cell Biochemistry and Biophysics · doi:10.1007/bf02738170 · Cited by 63

Amino acid sequence similarities of the mitochondrial short chain delta 3, delta 2-enoyl-CoA isomerase and peroxisomal multifunctional delta 3, delta 2-enoyl-CoA isomerase, 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase enzyme in rat liver. The proposed occurrence of isomerization and hydration in the same catalytic domain of the multifunctional enzyme

Palosaari, P. M., Vihinen, M., Mäntsälä, P., Alexson, S. E. H., Pihlajaniemi, T. A., & Hiltunen, J. K. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99081-2 · Cited by 62

In Mouse α-Methylacyl-CoA Racemase, the Same Gene Product Is Simultaneously Located in Mitochondria and Peroxisomes

Kotti, T. J., Savolainen, K., Helander, H. M., Yagi, A., Novikov, D. K., Kalkkinen, N., Conzelmann, E., Hiltunen, J. K., & Schmitz, W. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002067200 · Cited by 60

Changing Stereochemistry for a Metabolic Pathway in Vivo

Filppula, S. A., Sormunen, R. T., Hartig, A., Kunau, W., & Hiltunen, J. K. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.46.27453 · Cited by 57

Carnitine acyltransferases in rat liver peroxisomes

BIEBER, L. L., Krahling, J. B., Clarke, P., Valkner, K. J., & Tolbert, N. E. (1981) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(81)90494-x · Cited by 57

Crystal Structure of 2-Enoyl-CoA Hydratase 2 from Human Peroxisomal Multifunctional Enzyme Type 2

Koski, M. K., Haapalainen, A. M., Hiltunen, J. K., & Glumoff, T. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.11.009 · Cited by 57

NADPH-dependent reductive metabolism of cis-5 unsaturated fatty acids. A revised pathway for the beta-oxidation of oleic acid

Tserng, K., & Jin, S. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99001-0 · Cited by 53

A defect in glyoxysomal fatty acid β-oxidation reduces jasmonic acid accumulation in Arabidopsis

Afitlhile, M. M., Fukushige, H., Nishimura, M., & Hildebrand, D. F. (2005) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2005.03.016 · Cited by 53

Δ3,5-Δ2,4-Dienoyl-CoA Isomerase from Rat Liver

Filppula, S. A., Yagi, A., Kilpeläinen, S. H., Novikov, D., FitzPatrick, D. R., Vihinen, M., Valle, D. L., & Hiltunen, J. K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.1.349 · Cited by 50

The crystal structure of Δ3-Δ2-enoyl-CoA isomerase

Mursula, A. M., van Aalten, D. M. F., Hiltunen, J. K., & Wierenga, R. K. (2001) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.4671 · Cited by 50

α-Methylacyl-CoA Racemase from Mycobacterium tuberculosis

Savolainen, K., Bhaumik, P., Schmitz, W., Kotti, T. J., Conzelmann, E., Wierenga, R. K., & Hiltunen, J. K. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m409704200 · Cited by 49

Futile Cycling of Intermediates of Fatty Acid Biosynthesis toward Peroxisomal β-Oxidation in Saccharomyces cerevisiae

Marchesini, S., & Poirier, Y. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305574200 · Cited by 47

Molecular Identification and Characterization of the Arabidopsis Δ3,5,Δ2,4-Dienoyl-Coenzyme A Isomerase, a Peroxisomal Enzyme Participating in the β-Oxidation Cycle of Unsaturated Fatty Acids

Goepfert, S., Vidoudez, C., Rezzonico, E., Hiltunen, J. K., & Poirier, Y. (2005) · PLANT PHYSIOLOGY · doi:10.1104/pp.105.064311 · Cited by 47

Molecular Cloning and Characterization of Two Mouse Peroxisome Proliferator-activated Receptor α (PPARα)-regulated Peroxisomal Acyl-CoA Thioesterases

Westin, M., Alexson, S. E. H., & Hunt, M. C. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313863200 · Cited by 47

Comparison of the stability and substrate specificity of purified peroxisomal 3-oxoacyl-CoA thiolases A and B from rat liver

Antonenkov, V. D., Veldhoven, P. P. V., Waelkens, E., & Mannaerts, G. P. (1999) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(99)00003-7 · Cited by 46

Structural biology of the thioester-dependent degradation and synthesis of fatty acids

Bhaumik, P., Koski, M. K., Glumoff, T., Hiltunen, J. K., & Wierenga, R. K. (2005) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2005.10.010 · Cited by 44

Fusion and Fission, the Evolution of Sterol Carrier Protein-2

Edqvist, J., & Blomqvist, K. (2006) · Journal of Molecular Evolution · doi:10.1007/s00239-005-0086-3 · Cited by 42

Acyl-CoA Oxidase 1 from Arabidopsis thaliana. Structure of a Key Enzyme in Plant Lipid Metabolism

Pedersen, L., & Henriksen, A. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.10.062 · Cited by 42

Channeling of 3-hydroxy-4-trans-decenoyl coenzyme A on the bifunctional beta-oxidation enzyme from rat liver peroxisomes and on the large subunit of the fatty acid oxidation complex from Escherichia coli.

Yang, S., Cuebas, D. A., & Schulz, H. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66723-7 · Cited by 41

Yeast Peroxisomal Multifunctional Enzyme: (3R)-Hydroxyacyl-CoA Dehydrogenase Domains A and B Are Required for Optimal Growth on Oleic Acid

Qin, Y.-M., Marttila, M. S., Haapalainen, A. M., Siivari, K. M., Glumoff, T., & Hiltunen, J. K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.40.28619 · Cited by 41

Significance of the Reductase-dependent Pathway for the β-Oxidation of Unsaturated Fatty Acids with Odd-numbered Double Bonds

Shoukry, K., & Schulz, H. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.12.6892 · Cited by 40

Role and Organization of Peroxisomal β-Oxidation

Veldhoven, P. P. V., & Mannaerts, G. P. (2002) · Advances in experimental medicine and biology · doi:10.1007/0-306-46818-2_31 · Cited by 39

Chlorpromazine and carnitine-dependency of rat liver peroxisomal β-oxidation of long-chain fatty acids

Vamecq, J. (1987) · Biochemical Journal · doi:10.1042/bj2410783 · Cited by 35

The Peroxisomal Acyl-CoA Thioesterase Pte1p from Saccharomyces cerevisiae Is Required for Efficient Degradation of Short Straight Chain and Branched Chain Fatty Acids

Maeda, I., Delessert, S., Hasegawa, S., Seto, Y., Zuber, S., & Poirier, Y. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511762200 · Cited by 33

Peroxisomal Degradation of trans-Unsaturated Fatty Acids in the Yeast Saccharomyces cerevisiae

Gurvitz, A., Hamilton, B., Ruis, H., & Hartig, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m003305200 · Cited by 30

Intermediate Channeling on the Trifunctional β-Oxidation Complex from Pig Heart Mitochondria

Yao, K.-W., & Schulz, H. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.30.17816 · Cited by 30

Molecular cloning, gene structure and expression profile of two mouse peroxisomal 3-ketoacyl-CoA thiolase genes

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Binary Structure of the Two-Domain (3R)-Hydroxyacyl-CoA Dehydrogenase from Rat Peroxisomal Multifunctional Enzyme Type 2 at 2.38 Å Resolution

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