The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Applications of ATR-FTIR spectroscopic imaging to biomedical samples
Open accessAbstract
FTIR spectroscopic imaging in ATR (Attenuated Total Reflection) mode is a powerful tool for studying biomedical samples. This paper summarises recent advances in the applications of ATR-FTIR imaging to dissolution of pharmaceutical formulations and drug release. The use of two different ATR accessories to obtain chemical images of formulations in contact with water as a function of time is demonstrated. The innovative use of the diamond ATR accessory allowed in situ imaging of tablet compaction and dissolution. ATR-FTIR imaging was also applied to obtain images of the surface of skin and the spatial distribution of protein and lipid rich domains was obtained. Chemical images of cross-section of rabbit aorta were obtained using a diamond ATR accessory and the possibility of in situ imaging of arterial samples in contact with aqueous solution was demonstrated for the first time. This experiment opens an opportunity to image arterial samples in contact with solutions containing drug molecules. This approach may help in understanding the mechanisms of treatment of atherosclerosis.
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Citations
Cites
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Fourier Transform Spectroscopic Imaging Using an Infrared Focal-Plane Array Detector
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Imaging of colorectal adenocarcinoma using FT-IR microspectroscopy and cluster analysis
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FT-IR spectroscopic investigations of single cells on the subcellular level
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Infrared spectroscopic characterization of mineralized tissues
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Self-citationCombined approach of FTIR imaging and conventional dissolution tests applied to drug release
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Cited by
Zhang, X.-F., Liu, Z.-G., Shen, W., & Gurunathan, S. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17091534 · Cited by 3,220
Techniques for physicochemical characterization of nanomaterials
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ATR-FTIR spectroscopic imaging: recent advances and applications to biological systems
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Metadata
- Authors
- Kazarian, S. G., & Chan, K. L. A.
- Venue
- Biochimica et Biophysica Acta (BBA) - Biomembranes
- Publisher
- Elsevier BV
- Published
- 2006-07
- Volume
- 1758
- Issue
- 7
- Pages
- 858-867
- ISSN
- 0005-2736 (ISSN-L)
- OpenAlex
- W1967809548
- Cited by
- 379
- References
- 21
- FWCI
- 5.53
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
