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Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches
Open accessAbstract
Recent advances in nanoscience and nanotechnology radically changed the way we diagnose, treat, and prevent various diseases in all aspects of human life. Silver nanoparticles (AgNPs) are one of the most vital and fascinating nanomaterials among several metallic nanoparticles that are involved in biomedical applications. AgNPs play an important role in nanoscience and nanotechnology, particularly in nanomedicine. Although several noble metals have been used for various purposes, AgNPs have been focused on potential applications in cancer diagnosis and therapy. In this review, we discuss the synthesis of AgNPs using physical, chemical, and biological methods. We also discuss the properties of AgNPs and methods for their characterization. More importantly, we extensively discuss the multifunctional bio-applications of AgNPs; for example, as antibacterial, antifungal, antiviral, anti-inflammatory, anti-angiogenic, and anti-cancer agents, and the mechanism of the anti-cancer activity of AgNPs. In addition, we discuss therapeutic approaches and challenges for cancer therapy using AgNPs. Finally, we conclude by discussing the future perspective of AgNPs.
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Cites
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Cited by
Metal-Based Nanoparticles as Antimicrobial Agents: An Overview
Sánchez-López, E., Gomes, D., Esteruelas, G., Bonilla, L., Lopez-Machado, A. L., Galindo, R., Cano, A., Espina, M., Ettcheto, M., Camins, A., et al. (2020) · Nanomaterials · doi:10.3390/nano10020292 · Cited by 1,474
Ferdous, Z., & Nemmar, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072375 · Cited by 1,019
Advances in green synthesis of nanoparticles
Gour, A., & Jain, N. K. (2019) · Artificial Cells, Nanomedicine, and Biotechnology · doi:10.1080/21691401.2019.1577878 · Cited by 967
Current Research on Silver Nanoparticles: Synthesis, Characterization, and Applications
Dawadi, S., Katuwal, S., Gupta, A., Lamichhane, U., Thapa, R., Jaisi, S., Lamichhane, G., Bhattarai, D. P., & Parajuli, N. (2021) · Journal of Nanomaterials · doi:10.1155/2021/6687290 · Cited by 399
Nanoparticle-Mediated Combination Therapy: Two-in-One Approach for Cancer
Gurunathan, S., Kang, M.-H., Qasim, M., & Kim, J.-H. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19103264 · Cited by 367
Self-citation
Metadata
- Authors
- Zhang, X.-F., Liu, Z.-G., Shen, W., & Gurunathan, S.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2016-09-13
- Volume
- 17
- Issue
- 9
- Pages
- 1534
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2519678626
- Cited by
- 3,220
- References
- 5
- FWCI
- 63.88
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.