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Cited by 3,220

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches

Open access
Zhang, Xi-Feng, Liu, Zhi-Guo, Shen, Wei, Gurunathan, Sangiliyandi·2016·International Journal of Molecular Sciences

Abstract

Recent advances in nanoscience and nanotechnology radically changed the way we diagnose, treat, and prevent various diseases in all aspects of human life. Silver nanoparticles (AgNPs) are one of the most vital and fascinating nanomaterials among several metallic nanoparticles that are involved in biomedical applications. AgNPs play an important role in nanoscience and nanotechnology, particularly in nanomedicine. Although several noble metals have been used for various purposes, AgNPs have been focused on potential applications in cancer diagnosis and therapy. In this review, we discuss the synthesis of AgNPs using physical, chemical, and biological methods. We also discuss the properties of AgNPs and methods for their characterization. More importantly, we extensively discuss the multifunctional bio-applications of AgNPs; for example, as antibacterial, antifungal, antiviral, anti-inflammatory, anti-angiogenic, and anti-cancer agents, and the mechanism of the anti-cancer activity of AgNPs. In addition, we discuss therapeutic approaches and challenges for cancer therapy using AgNPs. Finally, we conclude by discussing the future perspective of AgNPs.

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Metadata

Authors
Zhang, X.-F., Liu, Z.-G., Shen, W., & Gurunathan, S.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2016-09-13
Volume
17
Issue
9
Pages
1534
ISSN
1422-0067 (ISSN-L)
OpenAlex
W2519678626
Cited by
3,220
References
5
FWCI
63.88
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches. https://app.cochat.ai/papers/10.3390/ijms17091534
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Zhang, X.-F., Liu, Z.-G., Shen, W., & Gurunathan, S. (2016). Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms17091534

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.