Aerobic fitness is associated with lower proportions of senescent blood T-cells in man

Spielmann, Guillaume, McFarlin, Brian K., O’Connor, Daniel P., Smith, Paula J.W., Pircher, Hanspeter, Simpson, Richard J.·2011·Brain, Behavior, and Immunity
DOI 10.1016/j.bbi.2011.07.226

Cited by (180)

Items 101–180 of 180

  1. T cell subsets’ distribution in elite karate athletes as a response to physical effort
    Dorota Kostrzewa‐Nowak, Rafał Buryta, Robert Nowak · 2018 · Journal of Medical Biochemistry
  2. Density of CD3+ and CD8+ Cells in the Microenvironment of Colorectal Cancer according to Prediagnostic Physical Activity
    David Renman, Björn Gylling, Linda Vidman, Stina Bodén, Karin Strigård, Richard Palmqvist, Sophia Harlid, Ulf Gunnarsson, Bethany R. Van Guelpen · 2021 · Cancer Epidemiology Biomarkers & Prevention
  3. Epigenetic Age Monitoring in Professional Soccer Players for Tracking Recovery and the Effects of Strenuous Exercise
    Robert T. Brooke, Thomas Köcher, Roland Zauner, Juozas Gordevičius, Milda Milčiūtė, Marc Nowakowski, Christian Haser, Thomas Blobel, Johanna Sieland, Daniel Langhoff et al. · 2025 · Aging Cell
  4. COVID-19 and physical activity: What is the relation between exercise immunology and the current pandemic situation?
    Guilherme Gomes Azizi, Marco Antônio Orsini, Sérgio Duarte Dortas, Paulo Alberto dos Santos Vieira, Ricardo Steiner De Carvalho, Cláudio Sérgio da Rocha Pires, Sebastião Carlos Ferreira Da Silva, Bruno Mendes de Sá Pinto, Carlos Eduardo Cardoso, Adalgiza Mafra Moreno et al. · 2020 · Revista Brasileira de Fisiologia do Exercício
  5. Physical Activity and Depression in Breast Cancer Patients: Mechanisms and Therapeutic Potential
    Anlong Li, Xinyi Zheng, Dajie Liu, Runze Huang, Han Ge, Ling Jie Cheng, Mingjun Zhang, Huaidong Cheng · 2025 · Current Oncology
  6. Assessment of selected exercise-induced CD3+ cell subsets and cell death parameters among soccer players
    Robert Nowak, Dorota Kostrzewa‐Nowak · 2019 · Journal of Medical Biochemistry
  7. Immunological parameters in elderly women: Correlations with aerobic power, muscle strength and mood state
    Vagner Raso, Valéria Maria Natale, Alberto José da Silva Duarte, Júlia María D’Andréa Greve, Roy Jesse Shephard · 2012 · Brain Behavior and Immunity
  8. Levels of cardiorespiratory fitness in men exerts strong impact on lymphocyte function after mitogen stimulation
    Gilson Pires Dorneles, Fábio Santos Lira, Pedro Roosevelt Torres Romão, Karsten Krüger, José Cesar Rosa Neto, Alessandra Peres, Barbara Moura Antunes · 2021 · Journal of Applied Physiology
  9. Mitochondrial Mass of Naïve T Cells Is Associated with Aerobic Fitness and Energy Expenditure of Active and Inactive Adults
    JESSICA R. ALLEY, Rudy J. Valentine, MARIAN L. KOHUT · 2022 · Medicine & Science in Sports & Exercise
  10. Exercise to Support Optimal Immune Function
    Forrest L. Baker, Richard J. Simpson · 2020 · ACSMʼs Health & Fitness Journal
  11. Cytomegalovirus Infection Impairs the Mobilization of Tissue-Resident Innate Lymphoid Cells into the Peripheral Blood Compartment in Response to Acute Exercise
    Eunhan Cho, Bailey M. Theall, James Stampley, Joshua Granger, Neil Michael Johannsen, Brian A. Irving, Guillaume Spielmann · 2021 · Viruses
  12. Using cardiorespiratory fitness to operationalize vitality: a path analysis on the hierarchical structure of intrinsic capacity
    Ruby Yu, Derek Lai, Grace Suk-Man Leung, Cecilia Tong, Jean Woo · 2024 · The journal of nutrition health & aging
  13. Global research landscape of telomere biology in infectious diseases: mechanistic links between host–pathogen interactions and immune ageing
    Theophilus Nang Wakai, Nina Ghislaine Yensii, Fabrice Banadzem Kernyuy, Mercy Bella-Omunagbe, Shalom Nwodo Chinedu, Israel Sunmola Afolabi · 2026 · Frontiers in Aging
  14. The aging immune system: Dysregulation, compensatory mechanisms, and prospects for intervention
    Ludmila Müller, Graham Pawelec · 2021 · Elsevier eBooks
  15. Can we jog our way to a younger-looking immune system?
    Suzi Hong · 2011 · Brain Behavior and Immunity
  16. The Impact of Different Types of Physical Effort on the Expression of Selected Chemokine and Interleukin Receptor Genes in Peripheral Blood Cells
    Robert Nowak, Alicja Trzeciak-Ryczek, Andrzej Ciechanowicz, Andrzej Brodkiewicz, Elżbieta Urasińska, Dorota Kostrzewa‐Nowak · 2023 · Cells
  17. Effect of a Multifactorial Weight Loss Intervention on HDL Cholesterol Efflux Capacity and Immunosenescence: A Randomized Controlled Trial
    Laura Díez-Ricote, Esther Cuadrado‐Soto, Andrés Pastor-Fernández, Gema de la Peña, Javier Martı́nez-Botas, Olga Castañer, Miguel Ángel Martínez‐González, Jordi Salas‐Salvadó, Pablo J. Fernández-Marcos, Diego Gómez‐Coronado et al. · 2024 · Journal of the American Nutrition Association
  18. Exercise role in improving the immune system and physical fitness during Corona pandemic period and associated exercise guidelines
    Sajad Ahmadizad, Minoo Bassami · 2020 · Journal of Sport and Exercise Physiology
  19. Exercise and Immunity: Beliefs and Facts
    Patricia López, Carolina Chamorro-Viña, Mariana Gómez-García, María Fernández-del-Valle · 2023 · Springer eBooks
  20. Higher Body Mass Index Is Associated With Greater Proportions of Effector CD8+ T Cells Expressing CD57 in Women Living With HIV
    Michael J. A. Reid, Sanjiv M. Baxi, Lila A. Sheira, ALAN L. LANDAY, Edward A. Frongillo, Adebola Adedimeji, Mardge H. Cohen, Eryka Wentz, Deborah Gustafson, Daniel J. Merenstein et al. · 2017 · JAIDS Journal of Acquired Immune Deficiency Syndromes
  21. Associations of Global Country Profiles and Modifiable Risk Factors with COVID-19 Cases and Deaths
    Samuel Joseph Burden, Josefien Rademaker, Benjamin David Weedon, Luke Whaymand, Helen Dawes, Alexander Jones · 2020 · medRxiv
  22. An exercise immune fitness test to unravel mechanisms of Post-Acute Sequelae of COVID-19
    Mario C.-H.K. Deng · 2023 · Expert Review of Clinical Immunology
  23. Physical exercise, the immune system and infection risk: implications for prehabilitation and rehabilitation for solid organ transplantation candidates and recipients
    NICOLETTE CLAIRE BISHOP · 2024 · Current Opinion in Organ Transplantation
  24. Reduced Naïve T Cell Numbers Correlate with Increased Low-Grade Systemic Inflammation During Ageing and Can be Modulated by Physical Activity
    Eugenio Merellano-Navarro, Alexandra Olate‐Briones, Leandra Norambuena-Mardones, Vicente Rojas-Ramos, Alexandra Márquez de la Plata-Luna, Jorge Y. Faúndez-Acuña, Javiera C Moraga, Noelia Escobedo, Andrés A. Herrada · 2021 · International Journal of Morphology
  25. Aging Immunity and the Impact of Physical Exercise
    Austin B. Bigley, Forrest L. Baker, Guillaume Spielmann, Richard J. Simpson · 2019 · Springer eBooks
  26. Aging Immunity and the Impact of Physical Exercise
    Guillaume Spielmann, Austin B. Bigley, Emily C. P. LaVoy, Richard J. Simpson · 2013 · Springer eBooks
  27. Lifestyle Interventions to Improve Immunesenescence
    David B. Bartlett, Kim M. Huffman · 2016 · Springer eBooks
  28. The Aging Immune System
    Ludmila Müller, Graham Pawelec · 2015 · Elsevier eBooks
  29. Excessive physical exercise caused a decrease in CD4+ and Hematopoietic Stem Cell (HSC) levels in Wistar rats
    Si Ngurah Oka Putrawan, I Made Jawi, I Wayan Putu Sutirta Yasa, Anak Agung Ngurah Subawa, Ida Bagus Putra Manuaba · 2022 · Bali Medical Journal
  30. The Evaluation of Physiopathological and Immunological Exercise Effects During Pandemic and Pathogenicity on Coronavirus COVID-19 (with Considerations and Instructions of Doing Related Physical Activity)
    Abolfazl Aghababaeyan, Sadegh Ali Azimi, Mohammad Bagher Nikzad · 2024 · Comprehensive Health and Biomedical Studies
  31. Modified High-Intensity Interval Training and its effects on immunometabolic regulation in sedentary young adults with overweight and obesity.
    Carmen Paulina Rodríguez-López, María Cristina González-Torres, Oralia Nájera-Medina · 2023 · Investigación Clínica
  32. An Exercise Immune Fitness Test to Unravel Disease Mechanisms—A Proof-of-Concept Heart Failure Study
    Galyna Bondar, Abhinandan Das Mahapatra, Tra-Mi Bao, Irina Silacheva, Adrian Hairapetian, Thomas Vu, Stephanie Su, Ananya Katappagari, G. Liana, Joshua Chandran et al. · 2024 · Journal of Clinical Medicine
  33. Differential effects of whole blood heat treatment on the ex vivo inflammatory profile of untrained and trained men
    Gilson Pires Dorneles, Keli Cristine Reiter, Aline Aparecida Zonin Dos Passos, Bruna Marmett, Igor Martins da Silva, Maeli Andressa Santos, Maurício da Silva Krause, Alessandra Peres, Pedro Roosevelt Torres Romão · 2021 · Cytokine
  34. Immunosenescence and exercise-mediated modulation of the innate immune response to Influenza infection in mice
    Shibani Naik · 2013 · Iowa State University Digital Repository (Iowa State University)
  35. Physical activity regulates the immune response to breast cancer by a hematopoietic stem cell-autonomous mechanism
    Lyne Khair, Katherine Hayes, Amanda A. Tutto, Amruta Samant, Lindsay M Ferreira, Tammy Nguyen, Michael A. Brehm, Louis M. Messina · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  36. Effect of aging and exercise on hTERT expression in thymus tissue of hTERT transgenic bacterial artificial chromosome mice
    Jeongjin Kim, Alexander Ahn, Jeffrey Y. Ying, Jesse Pollens-Voigt, Andrew T. Ludlow · 2024 · GeroScience
  37. Exploring Chronic Pain, Immune Dysfunction and Lifestyle: A Focus on T Cell Exhaustion and Senescence
    Yanthe Buntinx, Jolien Hendrix, Arne Wyns, Jente Van Campenhout, Huan-Yu Xiong, Thessa Laeremans, Sara Cuesta‐Sancho, Joeri L. Aerts, Jo Nijs, Andrea Polli · 2025 · Biomolecules
  38. Exercise Ameliorates Immunosenescence: From Mechanisms to Interventions
    Haili Xiao, Jianchang Ren · 2025 · Biology
  39. Exercise and tissue-resident memory T cells: from circulating numbers to spatial immune remodeling
    Enli Xie, Yushan He, Tainan Cao, Changchun Li, Zhiming Wang · 2026 · Frontiers in Immunology
  40. Impact of exercise intervention on immune function during aging
    Junyu Bai, Jinqiao Zhang · 2026 · Frontiers in Immunology
  41. The role of targeting cell senescence in vascular diseases and its potential application
    Hui-Yu Wang, Yang-Nan Ding, Ziyu Wei, Hou‐Zao Chen, De‐Pei Liu · 2022 · Scientia Sinica Vitae
  42. Association of Physical Activity level with the COVID-19 Incidence in Patients with Type 2 Diabetes
    Rastegar Hoseini, Zahra Hoseini, Elahe Bahmani, Mahsa Ahmadi Darmian · 2022 · Journal of Advances in Medical and Biomedical Research
  43. Age-related disease: Diabetes
    Allyson K. Palmer, James L. Kirkland · 2024 · Elsevier eBooks
  44. Physical activity affects DNA methylation-derived inflammation markers in a community-based Parkinson's disease study
    Yang Cheng Hu, Keren Zhang, Kimberly C. Paul, Jin Zhou, Jeff M. Bronstein, Cynthia Kusters, Beate R. Ritz · 2025 · Brain Behavior & Immunity - Health
  45. Relationship of Physical Activity Level with Quality of Life and General Health Among COVID-19 Recovered Individuals
    Mahnaz Azmodeh, Rastegar Hoseini, Ehsan Amiri · 2021 · Modern Care Journal
  46. Human Immune System and Exercise Medicine: Current Process and Future Directions
    Li Shen, Bairong Shen · 2022 · Springer eBooks
  47. Psychosocial and behavioral determinants of immune aging
    Jerrald L. Rector · 2015 · University of Birmingham Institutional Research Archive (University of Birmingham)
  48. The effects of exercise on intracellular Ca2+homeostasis, Ca2+-regulating gene expression and mitogen-induced cell proliferation of murine splenic lymphocytes
    Renyi Liu, Justus Liebig University Giessen · 2013 · University writing server of the Justus Liebig University Giessen (Justus-Liebig-Universität Gießen)
  49. The impact of exercise, adiposity and persistent viral infection on blood T-Cell phenotype and function
    Guillaume Spielmann · 2026 · Edinburgh Napier Research Repository (Edinburgh Napier University)
  50. Exercise and Immunosenescence
    Richard J. Simpson, Guillaume Spielmann · 2012 · Springer eBooks
  51. Exercício e mobilização de linfócitos T senescentes: Uma meta-análise
    Luciéle Guerra Minuzzi, Ana Maria Teixeira, José Pedro Ferreira · 2015 · Motricidade
  52. Impacto da prática da atividade física moderada regular no retardo da imunossenescência de idosos
    Léia Cristina Rodrigues da Silva · 2016 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  53. The role of physical activity in the molecular regulation of colon cancer risk
    Barnabas Shaw · 2015 · UEA Digital Repository (University of East Anglia)
  54. Beyond COVID-19: Preparing Fitness Centers for the Next Pandemic
    William Armstrong, Nishu N. Dayal, William A. Braun · 2021 · Strength and conditioning journal
  55. Effects of Physical Activity Status and Exercise Modality on the T-Cell and Monocyte Response to Acute Exercise in Older Adults
    Rachel Graff Levine · 2020
  56. Modulation of adaptive immunity through acute exercise, metabolism-targeting pharmacological agents, and chronic exercise training
    Jessica Alley · 2021 · Iowa State University Digital Repository (Iowa State University)
  57. The Role of Exercise and Physical Activity against COVID-19: A Narrative Review Study
    Diako Heidary, Aref Mehdipour · 2021 · Depiction of Health
  58. Impact of physical activity on immune function and inflammation in the elderly
    David B. Bartlett · 2014 · University of Birmingham Institutional Research Archive (University of Birmingham)
  59. Aging Immunity and the Impact of Physical Exercise
    Austin B. Bigley, Forrest L. Baker, Guillaume Spielmann, Richard J. Simpson · 2017 · Springer eBooks
  60. Immunologic
    Jeffrey A. Claridge, Brenda M. Zosa · 2017 · Springer eBooks
  61. Cytomegalovirus
    James Edward Turner · 2020 · Springer eBooks
  62. Effect of Exercise Program on Immunity System of Male Geriatrics with Immunodeficiency Disorders
    Ph.D. EMAD TAHA AZZA EL AZIZ, M.D. M. IBRAHEM SARAH Y. ABDELAZIZ · 2021 · The Medical Journal of Cairo University/The Medical Journal of Cairo University
  63. Immunosenescence
    Richard J. Simpson · 2012 · Springer eBooks
  64. Cytomegalovirus
    James Edward Turner · 2019 · Springer eBooks
  65. Impacto de una intervención sobre algunos parámetros de inflamación en pacientes con sobrepeso u obesidad con y sin síndrome metabólico
    Carmen Paulina Rodríguez López · 2019
  66. Cancer Rehabilitation or Physical Exercise Effect on Immune Function
    Shinichiro Morishita, Jack Brian Fu, Atsuhiro Tsubaki · 2022 · Springer eBooks
  67. Neuroimmunoregulation of Cancer: The Case for Multiple Myeloma
    Sheeba Ba Aqeel, Caitlin M. James, Jens Hillengass, Elizabeth A. Repasky · 2023 · Springer eBooks
  68. Bewegung und Gesundheit: Immunsystem im Fokus
    Barbara Strasser, Christopher Weyh, Karsten Krüger · 2024 · Springer eBooks
  69. Exercise immunology in 2 decades: systematic review and bibliometric analysis
    Suryanto Agung Prabowo, Ainun Zulfikar Rizki, Alvin Afandi, Mohammed Aljunaid, Junian Cahyanto Wibawa, Abdul Rachman Syam Tuasikal, Joseph Lobo, Novadri Ayubi · 2025
  70. Cancer Rehabilitation or Physical Exercise Effect on Immune Function
    Shinichiro Morishita, Jack Brian Fu, Atsuhiro Tsubaki · 2025 · Springer eBooks
  71. Lower CD8+ T‐cell senescence partially mediates the neuroprotection of higher aerobic fitness
    Bernadette A. Fausto, Elizabeth Akbulut, Mustafa Sheikh, Diana Grass, Nica Aquino, Luis Garza‐Martinez, Fanyu Hercules Tawe, Stephanie Ghaly, Alicia L Codrington, Andrew Gamil et al. · 2026 · Alzheimer s & Dementia Translational Research & Clinical Interventions
  72. Strength training modulates inflammation in pre-frail older women: Involvement of Treg cells
    Érica Leandro Marciano Vieira, Fernanda Matos Coelho, Sara Rezaei, Daniele Sirineu Pereira, Caio T. Fagundes, Juscelio Pereira Silva, Walderez O. Dutra, Mauro Martins Teixeira, Leani Souza Máximo Pereira, Albená Nunes Silva et al. · 2026 · Brain Behavior and Immunity Integrative
  73. Immunosenescence
    Richard J. Simpson · 2026 · Springer eBooks
  74. The Impact of Cardiorespiratory Fitness on Cytotoxic T Cell Metabolism and Function
    Justin C. Crane, Charles F. Hodgman, Rebekah M. Maddux, Heather L. Caslin, Mitzie Laughlin, Stacey L. Gorniak, Emily C. P. LaVoy · 2026 · Medicine & Science in Sports & Exercise
  75. Perioperative Therapie des operablen nicht-kleinzelligen Lungenkarzinoms
    Michelle Thieser, Frank Langer, Cornelia Kropf-Sanchen, Jan Stratmann · 2026 · Zeitschrift für Pneumologie
  76. CD31 + T‐cells express greater VEGF ‐A than CD31 − counterparts with expression exacerbated with advancing age in male adults
    Luke Stephen, Graham P. Wright, David J. Muggeridge, Melanie Leggate, Vignesh Nariyamattu Chandrakumar, Mark Ross · 2026 · Physiological Reports
  77. Association of objectively assessed physical activity with immune cell infiltration of the tumor microenvironment in non-metastatic colon cancer
    David Renman, Sofia Edin, Ulf Gunnarson, Niillas Blind, Karin Strigård, Richard Palmqvist · 2026 · International Journal of Colorectal Disease
  78. Multiomics profiling identifies molecular and cellular signatures of regular exercise in human peripheral blood
    Xuemei Song, Jingzhi Lv, Siliang Ge, Sihan Xu, Yisha Wu, Yuhui Zheng, Wenwen Zhou, Lifeng Li, Yan Zhang, Jiaqiang Zhang et al. · 2026 · Science Advances
  79. The Impact of Aerobic Exercise on Circulating T-Cells and NK-Cells in Colorectal Cancer Survivors: A Secondary Analysis of a Randomized Trial
    Eunhan Cho, Stephanie L. E. Compton, Shengping Yang, Mohamedtaki Abdulaziz Tejani, Ahmed Zakari, Justin C. Brown, Guillaume Spielmann · 2026 · Cancer Control
  80. Investigating Sports Activity and Training During the COVID-19 Era, Sports Care for Individuals Who Have Recovered from COVID-19, and Exercise Prescription for Special Groups
    Abolfazl Aghababaeian, Sadegh Ali Azimi, Mohammad Bagher Nikzad, Sadegh Abbasian, Mohammad Ali Sardar · 2026 · Asian Journal of Sports Medicine