Simpson, Richard J.

Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?

Duggal, N. A., Niemiro, G., Harridge, S. D. R., Simpson, R. J., & Lord, J. M. (2019) · Nature Reviews Immunology

Exercise and Physiological ResponsesPhysical Activity and Health

Cited by 436

Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions

Crucian, B. E., Choukèr, A., Simpson, R. J., Mehta, S., Marshall, G., Smith, S. M., Zwart, S. R., Heer, M., Ponomarev, S., Whitmire, A., et al. (2018) · Frontiers in Immunology

Spaceflight effects on biologySpace Exploration and Technology

Cited by 421

Exercise and the aging immune system

Simpson, R. J., Lowder, T. W., Spielmann, G., Bigley, A. B., LaVoy, E. C., & Kunz, H. (2012) · Ageing Research Reviews

Exercise and Physiological ResponsesImmune responses and vaccinations

Cited by 281

Aerobic fitness is associated with lower proportions of senescent blood T-cells in man

Spielmann, G., McFarlin, B. K., O’Connor, D. P., Smith, P. J. W., Pircher, H., & Simpson, R. J. (2011) · Brain, Behavior, and Immunity

Exercise and Physiological ResponsesT-cell and B-cell Immunology

Cited by 180

β2-Adrenergic receptor signaling mediates the preferential mobilization of differentiated subsets of CD8+ T-cells, NK-cells and non-classical monocytes in response to acute exercise in humans

Graff, R. M., Kunz, H. E., Agha, N. H., Baker, F. L., Laughlin, M., Bigley, A. B., Markofski, M. M., LaVoy, E. C., Katsanis, E., Bond, R. A., et al. (2018) · Brain, Behavior, and Immunity

Exercise and Physiological ResponsesCardiovascular and exercise physiology

Cited by 145

Toll-like receptor expression on classic and pro-inflammatory blood monocytes after acute exercise in humans

Simpson, R. J., McFarlin, B. K., McSporran, C., Spielmann, G., Hartaigh, B. Ó., & Guy, K. (2009) · Brain Behavior and Immunity

Exercise and Physiological ResponsesImmune Response and Inflammation

Cited by 125

High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects

Simpson, R. J., Florida-James, G. D., Cosgrove, C., Whyte, G. P., Macrae, S., Pircher, H., & Guy, K. (2007) · Journal of Applied Physiology

Exercise and Physiological ResponsesT-cell and B-cell Immunology

Cited by 101

Alterations in hematologic indices during long-duration spaceflight

Kunz, H., Quiriarte, H., Simpson, R. J., Ploutz-Snyder, R., McMonigal, K., Sams, C., & Crucian, B. (2017) · BMC Hematology

Spaceflight effects on biologyHigh Altitude and Hypoxia

Cited by 80

Training status and sex influence on senescent T-lymphocyte redistribution in response to acute maximal exercise

Brown, F. F., Bigley, A. B., Sherry, C., Neal, C. M., Witard, O. C., Simpson, R. J., & Galloway, S. D. R. (2014) · Brain, Behavior, and Immunity

Exercise and Physiological ResponsesCardiovascular and exercise physiology

Cited by 42

Sleep disruption and its effect on lymphocyte redeployment following an acute bout of exercise

Ingram, L. A., Simpson, R. J., Malone, E., & Florida-James, G. D. (2015) · Brain, Behavior, and Immunity

Sleep and Work-Related FatigueExercise and Physiological Responses

Cited by 38

Acute aerobic exercise in humans increases cytokine expression in CD27− but not CD27+ CD8+ T-cells

LaVoy, E. C., Bosch, J. A., Lowder, T. W., & Simpson, R. J. (2013) · Brain, Behavior, and Immunity

Exercise and Physiological ResponsesCardiovascular and exercise physiology

Cited by 33

The impact of 6-month training preparation for an Ironman triathlon on the proportions of naïve, memory and senescent T cells in resting blood

Cosgrove, C., Galloway, S. D. R., Neal, C., Hunter, A. M., McFarlin, B. K., Spielmann, G., & Simpson, R. J. (2012) · European Journal of Applied Physiology

Exercise and Physiological ResponsesSports Performance and Training

Cited by 26