Neural circuits subserving behavioral flexibility and their relevance to schizophrenia

A review of MRI findings in schizophrenia

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Blockade of NMDA Receptors and Apoptotic Neurodegeneration in the Developing Brain

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Dissociation in prefrontal cortex of affective and attentional shifts

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Medial Frontal Cortex Mediates Perceptual Attentional Set Shifting in the Rat

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Wisconsin Card Sorting revisited: Distinct neural circuits participating in different stages of the task identified by event-related functional magnetic resonance imaging

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The reduced neuropil hypothesis: a circuit based model of schizophrenia

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Supranormal Stimulation of D1Dopamine Receptors in the Rodent Prefrontal Cortex Impairs Spatial Working Memory Performance

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The Time of Prenatal Immune Challenge Determines the Specificity of Inflammation-Mediated Brain and Behavioral Pathology

Meyer, U., Nyffeler, M., Engler, A., Urwyler, A., Schedlowski, M., Knuesel, I., Yee, B. K., & Feldon, J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0099-06.2006 · Cited by 774

Organization of the afferent connections of the mediodorsal thalamic nucleus in the rat, related to the mediodorsal-prefrontal topography

Groenewegen, H. J. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90339-9 · Cited by 732

Cognitive Inflexibility After Prefrontal Serotonin Depletion

Clarke, H. F., Dalley, J. W., Crofts, H. S., Robbins, T. W., & Roberts, A. C. (2004) · Science · doi:10.1126/science.1094987 · Cited by 632

Orexin deficiency modulates cognitive flexibility in a sex‐dependent manner

Durairaja, A., & Fendt, M. (2020) · Genes Brain & Behavior · doi:10.1111/gbb.12707 · Cited by 41

Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy

Ferguson, B. R., Glick, C., & Huguenard, J. R. (2023) · eLife · doi:10.7554/elife.78349 · Cited by 33

Sex differences during place learning in the túngara frog

Liu, Y., & Burmeister, S. S. (2017) · Animal Behaviour · doi:10.1016/j.anbehav.2017.04.002 · Cited by 34

Bisphenol A impairs the memory function and glutamatergic homeostasis in a sex-dependent manner in mice: Beneficial effects of diphenyl diselenide

Jardim, N. S., Sartori, G., Sari, M. H. M., Müller, S. G., & Nogueira, C. W. (2017) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2017.05.035 · Cited by 34

DREADDs: The Power of the Lock, the Weakness of the Key. Favoring the Pursuit of Specific Conditions Rather than Specific Ligands

Goutaudier, R., Coizet, V., Carcenac, C., & Carnicella, S. (2019) · eNeuro · doi:10.1523/eneuro.0171-19.2019 · Cited by 34

Cognition- and circuit-based dysfunction in a mouse model of 22q11.2 microdeletion syndrome: effects of stress

Tripathi, A., Spedding, M., Schenker, E., Didriksen, M., Cressant, A., & Jay, T. M. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0687-z · Cited by 35

Behavioral flexibility is increased by optogenetic inhibition of neurons in the nucleus accumbens shell during specific time segmentsPreprint

Aquili, L., Liu, A. W., Shindou, M., Shindou, T., & Wickens, J. R. (2014) · Learning & Memory · doi:10.1101/lm.034199.113 · Cited by 35

Selective Role of the Putamen in Serial Reversal Learning in the Marmoset

Jackson, S. A. W., Horst, N. K., Axelsson, S. F. A., Horiguchi, N., Cockcroft, G. J., Robbins, T. W., & Roberts, A. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy276 · Cited by 35

Cannabis-Induced Hypodopaminergic Anhedonia and Cognitive Decline in Humans: Embracing Putative Induction of Dopamine Homeostasis

Blum, K., Khalsa, J. H., Cadet, J. L., Baron, D. A., Bowirrat, A., Boyett, B., Lott, L., Brewer, R., Gondré‐Lewis, M. C., Bunt, G. C., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.623403 · Cited by 32

Cerebellar contribution to higher and lower order rule learning and cognitive flexibility in mice

Dickson, P. E., Cairns, J., Goldowitz, D., & Mittleman, G. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.03.040 · Cited by 36

Genetic Variation in the Psychiatric Risk Gene CACNA1C Modulates Reversal Learning Across Species

Sykes, L., Haddon, J. E., Lancaster, T. M., Sykes, A., Azzouni, K., Ihssen, N., Moon, A. L., Lin, T. E., Linden, D. E. J., Owen, M. J., et al. (2018) · Schizophrenia Bulletin · doi:10.1093/schbul/sby146 · Cited by 32

Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome

Dickson, P. E., Corkill, B., McKimm, E., Miller, M. M., Calton, M. A., Goldowitz, D., Blaha, C. D., & Mittleman, G. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.05.060 · Cited by 30

Neuronal circuits and physiological roles of the basal ganglia in terms of transmitters, receptors and related disorders

Yamada, K., TAKAHASHI, S. Y., Karube, F., Fujiyama, F., Kobayashi, K., Nishi, A., & Momiyama, T. (2016) · The Journal of Physiological Sciences · doi:10.1007/s12576-016-0445-4 · Cited by 29

Altered Corticolimbic Control of the Nucleus Accumbens by Long-term Δ9-Tetrahydrocannabinol Exposure

Hwang, E.-K., & Lupica, C. R. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.07.024 · Cited by 29

Hypofrontality and Posterior Hyperactivity in Early Schizophrenia: Imaging and Behavior in a Preclinical Model

Kaneko, G., Sanganahalli, B. G., Groman, S. M., Wang, H., Coman, D., Rao, J. U., Hermán, P., Jiang, L., Rich, K. M., de Graaf, R. A., et al. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.05.019 · Cited by 30

Subunit-specific NMDAR antagonism dissociates schizophrenia subtype-relevant oscillopathies associated with frontal hypofunction and hippocampal hyperfunction

Pittman-Polletta, B., Hu, K., & Kocsis, B. (2018) · Scientific Reports · doi:10.1038/s41598-018-29331-8 · Cited by 29

Stress-induced impairments in prefrontal-mediated behaviors and the role of the N-methyl-d-aspartate receptor

Graybeal, C., Kiselycznyk, C., & Holmes, A. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.02.042 · Cited by 30

Strain differences in profiles of dopaminergic neurotransmission in the prefrontal cortex of the BALB/C vs. C57Bl/6 mice: Consequences of stress and afobazole

Anderzhanova, E. A., Bächli, H., Бунеева, О. А., Narkevich, V. B., Medvedev, A. E., Thoeringer, C. K., Wotjak, C. T., & Кудрин, В. С. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.03.015 · Cited by 28

Cortico-limbic–striatal contribution after response and reversal learning: A metabolic mapping study

Fidalgo, C., Conejo, N. M., González‐Pardo, H., & Arias, J. L. (2010) · Brain Research · doi:10.1016/j.brainres.2010.10.066 · Cited by 27

Calcium channels as therapeutic targets

Belardetti, F., & Zamponi, G. W. (2012) · Wiley Interdisciplinary Reviews Membrane Transport and Signalling · doi:10.1002/wmts.38 · Cited by 27

Lesions to the ventral, but not the dorsal, medial prefrontal cortex enhance latent inhibition

George, D. N., Duffaud, A. M., Pothuizen, H. H. J., Haddon, J. E., & Killcross, S. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07178.x · Cited by 27

N-methyl-D-aspartate receptor-mediated glutamate transmission in nucleus accumbens plays a more important role than that in dorsal striatum in cognitive flexibility

Ding, X., Qiao, Y., Piao, C., Zheng, X., Liu, Z., & Liang, J. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00304 · Cited by 26

Impact of partial dopamine depletion on cognitive flexibility in BDNF heterozygous mice

Parikh, V., Naughton, S. X., Yegla, B., & Guzman, D. M. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4229-6 · Cited by 29

Moderate prenatal alcohol exposure alters the number and function of GABAergic interneurons in the murine orbitofrontal cortex

Kenton, J. A., Ontiveros, T., Bird, C. W., Valenzuela, C. F., & Brigman, J. L. (2020) · Alcohol · doi:10.1016/j.alcohol.2020.06.001 · Cited by 26

Acute Vagus Nerve Stimulation Facilitates Short Term Memory and Cognitive Flexibility in Rats

Driskill, C. M., Childs, J. E., Itmer, B., Rajput, J. S., & Kroener, S. (2022) · Brain Sciences · doi:10.3390/brainsci12091137 · Cited by 28

Long-term memory, synaptic plasticity and dopamine in rodent medial prefrontal cortex: Role in executive functions

Sheynikhovich, D., Otani, S., Bai, J., & Arleo, A. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.1068271 · Cited by 31

Maternal Separation Induces Alterations in Reversal Learning and Brain-Derived Neurotrophic Factor Expression in Adult Rats

Xue, X., Shao, S., Wang, W., & Shao, F. (2013) · Neuropsychobiology · doi:10.1159/000356188 · Cited by 26

Impairments in set-shifting but not reversal learning in the neonatal ventral hippocampal lesion model of schizophrenia: further evidence for medial prefrontal deficits

Placek, K., Dippel, W. C., Jones, S., & Brady, A. M. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.08.034 · Cited by 25

The Reelin (RELN) gene is associated with executive function in healthy individuals.

Baune, B. T., Konrad, C., Suslow, T., Domschke, K., Birosova, E., Sehlmeyer, C., & Beste, C. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.08.002 · Cited by 25

Ketamine-Treatment During Late Adolescence Impairs Inhibitory Synaptic Transmission in the Prefrontal Cortex and Working Memory in Adult Rats

Pérez, M. Á., Morales, C., Santander, O., García, F., Gómez, I., Peñaloza‐Sancho, V., Fuentealba, P., Dagnino‐Subiabre, A., Moya, P. R., & Fuenzalida, M. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00372 · Cited by 24

Nucleus accumbens dopamine D2-receptor expressing neurons control behavioral flexibility in a place discrimination task in the IntelliCagePreprint

Macpherson, T., Morita, M., Wang, Y., Sasaoka, T., Sawa, A., & Hikida, T. (2016) · Learning & Memory · doi:10.1101/lm.042507.116 · Cited by 25

M 1 -selective muscarinic allosteric modulation enhances cognitive flexibility and effective salience in nonhuman primates

Hassani, S. A., Neumann, A. R., Russell, J. K., Jones, C. K., & Womelsdorf, T. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2216792120 · Cited by 21

Deletion of glycine transporter 1 (GlyT1) in forebrain neurons facilitates reversal learning: Enhanced cognitive adaptability?

Singer, P., Boison, D., Möhler, H., Feldon, J., & Yee, B. K. (2009) · Behavioral Neuroscience · doi:10.1037/a0016676 · Cited by 25

Blockade of glycine transporter 1 by SSR-504734 promotes cognitive flexibility in glycine/NMDA receptor-dependent manner

Nikiforuk, A., Kos, T., Rafa, D., Behl, B., Bespalov, A., & Popik, P. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.04.010 · Cited by 24

Subtype-selective nicotinic acetylcholine receptor agonists can improve cognitive flexibility in an attentional set shifting task

Wood, C., Kohli, S., Malcolm, E. M., Allison, C., & Shoaib, M. C. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.01.006 · Cited by 27

Catecholaminergic modulation of indices of cognitive flexibility: A pharmaco-tDCS study

Dennison, O., Gao, J., Lim, L. W., Stagg, C. J., & Aquili, L. (2018) · Brain stimulation · doi:10.1016/j.brs.2018.12.001 · Cited by 25

The initial stage of reversal learning is impaired in mice hemizygous for the vesicular glutamate transporter (VGluT1)

Granseth, B., Andersson, F. K., & Lindström, S. H. (2015) · Genes, Brain and Behavior · doi:10.1111/gbb.12230 · Cited by 23

Performance in hippocampus- and PFC-dependent cognitive domains are not concomitantly impaired in rats exposed to 20 cGy of 1 GeV/n 56Fe particles

Britten, R. A., Miller, V. D., Hadley, M. M., Jewell, J. S., & Macadat, E. (2016) · Life Sciences in Space Research · doi:10.1016/j.lssr.2016.06.005 · Cited by 23

Differential Plasticity in Auditory and Prefrontal Cortices, and Cognitive-Behavioral Deficits Following Noise-Induced Hearing Loss

Wieczerzak, K. B., Patel, S. V., MacNeil, H., Scott, K. E., Schormans, A. L., Hayes, S. H., Herrmann, B., & Allman, B. L. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.11.019 · Cited by 25

Dopamine and Serotonin Interactively Modulate Prefrontal Cortex Neurons In Vitro

Pietro, N. C. D., & Seamans, J. K. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.08.007 · Cited by 23

Touchscreen-paradigm for mice reveals cross-species evidence for an antagonistic relationship of cognitive flexibility and stability

Richter, S. H., Vogel, A. S., Ueltzhöffer, K. J., Muzzillo, C., Vogt, M. A., Lankisch, K., Armbruster‐Genc, D., Riva, M. A., Fiebach, C. J., Gass, P., et al. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00154 · Cited by 22

Local blockade of NMDA receptors in the rat prefrontal cortex increases c-Fos expression in multiple subcortical regions

Nowak, K., Meyza, K. Z., Nikolaev, E., Hunt, M. J., & Kasicki, S. (2012) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2012-1894 · Cited by 22

Medium spiny neurons of the anterior dorsomedial striatum mediate reversal learning in a cell-type-dependent manner

Wang, X., Qiao, Y., Dai, Z., Sui, N., Shen, F., Zhang, J., & Liang, J. (2018) · Brain Structure and Function · doi:10.1007/s00429-018-1780-4 · Cited by 22

Effects of D- and L-govadine on the disruption of touchscreen object-location paired associates learning in rats by acute MK-801 treatment

Lins, B. R., Phillips, A. G., & Howland, J. G. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4064-1 · Cited by 21

Behavioral flexibility predicts increased ability to resist excessive methamphetamine self‐administration

Istin, M., Thiriet, N., & Solinas, M. (2016) · Addiction Biology · doi:10.1111/adb.12384 · Cited by 21

Prefrontal Theta Oscillations Promote Selective Encoding of Behaviorally Relevant Events

Jarovi, J., Volle, J., Yu, X., Guan, L., & Takehara‐Nishiuchi, K. (2018) · eNeuro · doi:10.1523/eneuro.0407-18.2018 · Cited by 24

Thalamostriatal System Controls the Acquisition, Performance, and Flexibility of Learning Behavior

Kato, S., Nishizawa, K., & Kobayashi, K. (2021) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2021.729389 · Cited by 20

Overexpression of αCaMKII impairs behavioral flexibility and NMDAR-dependent long-term depression in the medial prefrontal cortex

Ma, J., Duan, Y., Qin, Z., Wang, J., Liu, W., Xu, M., Zhou, S., & Cao, X. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.09.051 · Cited by 19

Performance on a strategy set shifting task in rats following adult or adolescent cocaine exposure

Kantak, K. M., Barlow, N., Tassin, D. H., Brisotti, M. F., & Jordan, C. J. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3598-y · Cited by 20

Different dosing regimens of repeated ketamine administration have opposite effects on novelty processing in rats

Schumacher, A., Sivanandan, B., Tolledo, E. C., Woldegabriel, J. T., & Ito, R. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.03.007 · Cited by 22

Abundant collateralization of temporal lobe projections to the accumbens, bed nucleus of stria terminalis, central amygdala and lateral septum

Reichard, R. A., Subramanian, S., Desta, M. T., Sura, T. A., Becker, M. L., Ghobadi, C. W., Parsley, K. P., & Zahm, D. S. (2016) · Brain Structure and Function · doi:10.1007/s00429-016-1321-y · Cited by 23

Behavioural inflexibility in a comorbid rat model of striatal ischemic injury and mutant hAPP overexpression

Levit, A., Regis, A. M., Garabon, J. R., Oh, S., Desai, S. J., Rajakumar, N., Hachinski, V., Ağca, Y., Agca, C., Whitehead, S. N., et al. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.07.006 · Cited by 21

Oxytocin and vasopressin in the hippocampus

Zăgrean, A., Georgescu, I.-A., Ieșanu, M. I., Ionescu, R.-B., Haret, R. M., Panaitescu, A. M., & Zăgrean, L. (2022) · Vitamins and hormones · doi:10.1016/bs.vh.2021.11.002 · Cited by 20

Chronic stress causes striatal disinhibition mediated by SOM-interneurons in male mice

Rodrigues, D., Jacinto, L., Falcão, M., Castro, A. C., Cruz, A., Santa, C., Manadas, B. J., Marques, F., Sousa, N., & Monteiro, P. (2022) · Nature Communications · doi:10.1038/s41467-022-35028-4 · Cited by 22

A preclinical assessment of d.l-govadine as a potential antipsychotic and cognitive enhancer

Lapish, C. C., Belardetti, F., Ashby, D. M., Ahn, S., Butts, K. A., So, K., Macrae, C. M., Hynd, J. J., Miller, J. J., & Phillips, A. G. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114571100157x · Cited by 19

Age-dependent shift in spontaneous excitation-inhibition balance of infralimbic prefrontal layer II/III neurons is accelerated by early life stress, independent of forebrain mineralocorticoid receptor expression

Karst, H., Sarabdjitsingh, R. A., van der Weerd, N., Feenstra, E., Damsteegt, R., & Joëls, M. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108294 · Cited by 21

Calcium chloride mimics the effects of acamprosate on cognitive deficits in chronic alcohol-exposed mice

Pradhan, G., Melugin, P. R., Wu, F., Fang, H. M., Weber, R. E., & Kroener, S. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4900-1 · Cited by 21

Procognitive effects of varenicline in the animal model of schizophrenia depend on α4β2- and α7-nicotinic acetylcholine receptors

Potasiewicz, A., Gołębiowska, J., Popik, P., & Nikiforuk, A. (2018) · Journal of Psychopharmacology · doi:10.1177/0269881118812097 · Cited by 19

Cortical thickness, gray matter volume, and white matter anisotropy and diffusivity in schizophrenia

Murakami, M., Takao, H., Abe, O., Yamasue, H., Sasaki, H., Gonoi, W., Takano, Y., Takei, K., Kasai, K., & Ohtomo, K. (2011) · Neuroradiology · doi:10.1007/s00234-010-0830-2 · Cited by 19

Effects of acute administration of the GABA(B) receptor agonist baclofen on behavioral flexibility in rats

Beas, B. S., Setlow, B., & Bizon, J. L. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4321-y · Cited by 18

α4βδ GABAA receptors reduce dendritic spine density in CA1 hippocampus and impair relearning ability of adolescent female mice: Effects of a GABA agonist and a stress steroid

Afroz, S., Shen, H., & Smith, S. S. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.01.051 · Cited by 18

Set shifting in a rodent model of attention-deficit/hyperactivity disorder.

Chess, A. C., Raymond, B. E., Gardner‐Morse, I., Stefani, M. R., & Green, J. T. (2011) · Behavioral Neuroscience · doi:10.1037/a0023571 · Cited by 17

Differential effects of social and novelty enrichment on individual differences in impulsivity and behavioral flexibility

Wang, M. Z., Marshall, A. T., & Kirkpatrick, K. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.03.028 · Cited by 22

Impulsiveness, postprandial blood glucose, and glucoregulation affect measures of behavioral flexibility

Riby, L. M., Ong, D. L. T., Azmie, N. B. M., Ooi, E. L., Regina, C., Yeo, E. K. W., Massa, J., & Aquili, L. (2017) · Nutrition Research · doi:10.1016/j.nutres.2017.10.011 · Cited by 16

Roles of the ventral hippocampus and medial prefrontal cortex in spatial reversal learning and attentional set-shifting

Černotová, D., Stuchlı́k, A., & Svoboda, J. (2021) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2021.107477 · Cited by 24

The role of striatal dopamine D2/3 receptors in cognitive performance in drug-free patients with schizophrenia

Veselinović, T., Vernaleken, I., Janouschek, H., Cumming, P. D., Paulzen, M., Mottaghy, F. M., & Gründer, G. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4916-6 · Cited by 16

The ventral hippocampus is required for behavioral flexibility but not for allocentric/egocentric learning

Torres‐Berrío, A., Vargas-López, V., & López-Canul, M. (2018) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2018.12.011 · Cited by 18

MCH and apomorphine in combination enhance action potential firing of nucleus accumbens shell neurons in vitro

Hopf, F. W., Seif, T., Chung, S., & Civelli, O. (2013) · PeerJ · doi:10.7717/peerj.61 · Cited by 16

Persistent cognitive and morphological alterations induced by repeated exposure of adolescent rats to the abused inhalant toluene

Braunscheidel, K. M., Gass, J. T., Mulholland, P. J., Floresco, S., & Woodward, J. J. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.07.007 · Cited by 17

Lost in translation: no effect of repeated optogenetic cortico-striatal stimulation on compulsivity in rats

de Oliveira, A. R., Reimer, A. E., Simandl, G. J., Nagrale, S. S., & Widge, A. S. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01448-x · Cited by 14

Role of calcineurin in inhibiting disadvantageous associations

Shaw, J., Matlovich, N., Rushlow, W. J., Cain, P., & Rajakumar, N. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2011.12.010 · Cited by 14

The effects of PDE10 inhibition on attentional set-shifting do not depend on the activation of dopamine D1 receptors

Nikiforuk, A., Potasiewicz, A., Rafa, D., Drescher, K. U., Bespalov, A., & Popik, P. (2015) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000201 · Cited by 15

Increased perseverative errors following high-definition transcranial direct current stimulation over the ventrolateral cortex during probabilistic reversal learning

Albein‐Urios, N., Chase, H. W., Clark, L., Kirkovski, M., Davies, C., & Enticott, P. G. (2019) · Brain stimulation · doi:10.1016/j.brs.2019.02.013 · Cited by 15

Rapid, automated, and experimenter-free touchscreen testing reveals reciprocal interactions between cognitive flexibility and activity-based anorexia in female rats

Huang, K., Milton, L. K., Dempsey, H., Power, S. J., Conn, K., Andrews, Z. B., & Foldi, C. J. (2023) · eLife · doi:10.7554/elife.84961 · Cited by 14

Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists

Chvojková, M., Kolář, D., Kovacova, K., Cejkova, L., Misiachna, A., Hakenova, K., Górecki, L., Hořák, M., Korábečný, J., Soukup, O., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116821 · Cited by 14

Characterization of striatal dopamine projections across striatal subregions in behavioral flexibility

van der Merwe, R. K., Nadel, J. A., Copes‐Finke, D., Pawelko, S. S., Scott, J. S., Ghanem, M. M., Fox, M., Morehouse, C., McLaughlin, R., Maddox, C., et al. (2023) · European Journal of Neuroscience · doi:10.1111/ejn.15910 · Cited by 16

Inter-individual differences in decision-making, flexible and goal-directed behaviors: novel insights within the prefronto-striatal networks

Fitoussi, A., Renault, P., Le Moine, C., Coutureau, E., Cador, M., & Dellu-Hagedorn, F. (2018) · Brain Structure and Function · doi:10.1007/s00429-017-1530-z · Cited by 14

The stoned age: Sex differences in the effects of adolescent cannabinoid exposure on prefrontal cortex structure and function in animal models

Ginder, D. E., Wright, H. R., & McLaughlin, R. J. (2021) · International review of neurobiology · doi:10.1016/bs.irn.2021.07.005 · Cited by 15

A meta-analytic study of the effects of early maternal separation on cognitive flexibility in rodent offspring

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Average spectral power changes at the hippocampal electroencephalogram in schizophrenia model induced by ketamine

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Cerebral and behavioral signs of impaired cognitive flexibility and stability in schizophrenia spectrum disorders

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A behavioral task for investigating action discovery, selection and switching: comparison between types of reinforcer

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Tcf4 transgenic female mice display delayed adaptation in an auditory latent inhibition paradigm

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Neonatal immune activation by lipopolysaccharide causes inadequate emotional responses to novel situations but no changes in anxiety or cognitive behavior in Wistar rats

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Nucleus Accumbens Core Dopamine D2 Receptor-Expressing Neurons Control Reversal Learning but Not Set-Shifting in Behavioral Flexibility in Male Mice

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Pathways to similar executive impairment: Comparison of schizophrenia patients and healthy aging individuals

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Overexpression of βCaMKII impairs behavioral flexibility and NMDAR-dependent long-term depression in the dentate gyrus

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Spatial learning and flexibility in 129S2/SvHsd and C57BL/6J mouse strains using different variants of the Barnes maze

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Composition of long chain polyunsaturated fatty acids (LC-PUFAs) in different encephalic regions and its association with behavior in spontaneous hypertensive rat (SHR)

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Flexibility in spatial cognition of rat

Staňková, A. (2015) · Digital Repository (National Repository of Grey Literature)

Attention regulation and behavioural flexibility in rats, with relevance to schizophrenia

Whyte, A. J. (2017) · St Andrews Research Repository (St Andrews Research Repository)

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Animal modeling for schizophrenia: Stereotyped-rotations induced by ketamine in adult male rats are significantly increased after postnatal inactivation of the prefrontal cortex but not of the ventral subiculum.

Heintz, S., & Louilot, A. (2024) · HAL · doi:10.13140/rg.2.2.14994.00964

Infusions of Nerve Growth Factor Into the Developing Frontal Cortex Leads to Deficits in Behavioral Flexibility and Increased Perseverance

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