The P2X7 receptor: A main player in inflammation
Adinolfi, Elena, Giuliani, Anna Lisa, De Marchi, Elena, Pegoraro, Anna, Orioli, Elisa, Di Virgilio, Francesco·2018·Biochemical Pharmacology
Cited by (384)
Items 201–300 of 384
- Extracellular ATP (eATP) inhibits the progression of endometriosis and enhances the immune function of macrophagesLing Zhou, E. Cai, Huiping Liu, Hongyan Cheng, Xue Ye, Honglan Zhu, Xiaohong Chang · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Caffeine reduces viability, induces apoptosis, inhibits migration and modulates the CD39/CD73 axis in metastatic cutaneous melanoma cellsDaiane Manica, Gilnei Bruno da Silva, Jussara de Lima, Joana Vitória Cassol, Paula Dallagnol, Rafael Antônio Narzetti, Marcelo Moreno, Margarete Dulce Bagatini · 2023 · Purinergic Signalling
- Dexmedetomidine Alleviates Acute Stress-Induced Acute Kidney Injury by Attenuating Inflammation and Oxidative Stress via Inhibiting the P2X7R/NF-κB/NLRP3 Pathway in RatsHaotian Yang, Yuan Zhao, Yongping Chen, Tianyuan Yang, Xinyi Dou, Junfeng Li, Guiyan Yang, Guofeng Feng, Hao Fang, Honggang Fan et al. · 2024 · Inflammation
- Purinergic receptor ligands: the cytokine storm attenuators, potential therapeutic agents for the treatment of COVID-19Malek Zarei, Navideh Sahebi Vaighan, Seyed Ali Ziai · 2021 · Immunopharmacology and Immunotoxicology
- Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channelWaldemar Schäfer, Tobias Stähler, Carolina Pinto-Espinoza, Welbeck Danquah, Jan Knop, Björn Rissiek, Friedrich Haag, Friedrich Koch‐Nolte · 2022 · Frontiers in Pharmacology
- Bullatine A has an antidepressant effect in chronic social defeat stress mice; Implication of microglial inflammasomeJiarui Zhang, Shu-Yuan Yin, Zu-Qi Shen, Bing Li, Yu‐Qiu Zhang, Jin Ming Yu · 2023 · Brain Research Bulletin
- Pterostilbene exerts cytotoxicity on activated hepatic stellate cells by inhibiting excessive proliferation through the crosstalk of Sirt1 and STAT3 pathwaysJiayi Dou, Haozhen Cui, Zhenyu Cui, Meiyan Xuan, Chong Gao, Zhaoxu Li, Li‐Hua Lian, Ji‐Xing Nan, Yan‐Ling Wu · 2023 · Food and Chemical Toxicology
- Purinergic signaling creates an anti-inflammatory profile in spleens of grass carp Ctenopharyngodon idella naturally infected by Saprolegnia parasitica: An attempt to prevent ATP pro-inflammatory effectsCarine F. Souza, Matheus D. Baldissera, Lorenzo B. Abbad, Maria Izabel de Ugalde Marques da Rocha, Marcelo Leite da Veiga, Aleksandro Schafer da Silva, Bernardo Baldisserotto · 2019 · Microbial Pathogenesis
- Multi-walled carbon nanotubes induce IL-1β secretion by activating hemichannels-mediated ATP release in THP-1 macrophagesJingpu Fan, Yiyong Chen, Di Yang, Jie Shen, Xinbiao Guo · 2020 · Nanotoxicology
- Metformin alleviates hydrogen peroxide–induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neuronsGang Wang, Shurui Chen, Zhenya Shao, Yankun Li, Wei Wang, Liang Mao, Jian Li, Xifan Mei · 2020 · Canadian Journal of Physiology and Pharmacology
- Amphiphilic anti-SARS-CoV-2 drug remdesivir incorporates into the lipid bilayer and nerve terminal membranes influencing excitatory and inhibitory neurotransmissionNatalia V. Krisanova, Natalia Pozdnyakova, Artem O. Pastukhov, Marina Dudarenko, Oleg Ya. Shatursky, Olena Gnatyuk, Uliana Afonina, Kyrylo A. Pyrshev, Г. И. Довбешко, Semen O. Yesylevskyy et al. · 2022 · Biochimica et Biophysica Acta (BBA) - Biomembranes
- Pannexin 3 activates P2X7 receptor to mediate inflammation and cartilage matrix degradation in temporomandibular joint osteoarthritisJialing Xiao, Yali Li, Jie Zhang, Guochao Xu, Jianxing Zhang · 2023 · Cell Biology International
- Alpha linolenic acid intake alleviates myocardial ischemia/reperfusion injury via the P2X7R/NF-κB signalling pathwayShuo Wang, Chaxian Liu, Chengxin Gong, Tao Li, Jiani Zhao, Wen Xiao, Yuanyuan Liu, Shanping Peng, Chaopeng Xiong, Rumeng Wang et al. · 2018 · Journal of Functional Foods
- Notopterol Ameliorates Hyperuricemia-Induced Cardiac Dysfunction in MiceQian Wang, Dewei Peng, Bingyu Huang, Lintong Men, Tao Jiang, Shengqi Huo, Moran Wang, Junyi Guo, Jiagao Lv, Lin Li · 2023 · Pharmaceuticals
- Calycosin limits hepatic fibrogenesis via KLF15 dependent repression of P2X7R in thioacetamide-induced hepatic fibrosisJin-Jin Zhang, Wanling Wang, Jiang‐Tao Zhong, Haiming Sun, Yu-Chen Jiang, Yue Shang, Jian Song · 2025 · Journal of Ethnopharmacology
- Naringenin alleviates bone cancer pain in rats via down-regulating spinal P2X7R /PI3K/AKT signaling: involving suppression in spinal inflammationJiangang Song, Lv Liu · 2021 · Molecular & Cellular Toxicology
- P2X7 receptor deficiency attenuates cisplatin-induced kidney injury via inhibiting NLRP3 inflammasome activationYingying Qian, Ning Zhao, Ming Wang, Zhiguo Zou, Kewei Xie · 2024 · Biochemical Pharmacology
- Association of Hypomorphic P2X7 Receptor Genotype With AgeJuana María Sanz, Simonetta Falzoni, Mario Luca Morieri, Angelina Passaro, Giovanni Zuliani, Francesco Di Virgilio · 2020 · Frontiers in Molecular Neuroscience
- Use of Humanized Mouse Models to Investigate the Roles of Purinergic Signaling in Inflammation and ImmunityRonald Sluyter, Debbie Watson · 2020 · Frontiers in Pharmacology
- Betulin Targets Lipin1/2-Meidated P2X7 Receptor as a Therapeutic Approach to Attenuate Lipid Accumulation and MetaflammationJia-Yi Dou, Yuchen Jiang, Zhong-He Hu, Kun-Chen Yao, Ming-Hui Yuan, Xiao-Xue Bao, Mei-Jie Zhou, Yue Liu, Zhaoxu Li, Li‐Hua Lian et al. · 2021 · Biomolecules & Therapeutics
- Progress in the relationship between P2X7R and colorectal cancerXue Bai, Xinyu Li, Cuicui Qiao, Yiqing Tang, Ronglan Zhao, Xiaoxiang Peng · 2022 · Molecular Biology Reports
- Schisandrin B Alleviates Diabetic Cardiac Autonomic neuropathy Induced by P2X7 Receptor in Superior Cervical Ganglion via NLRP3Zhihua Zhang, Hongmin Guo, Zihui Hu, Congfa Zhou, Qixing Hu, Hao Yang Peng, Gan Tang, Zehao Xiao, Lingzhi Pi, Guilin Li · 2023 · Disease Markers
- The price of P2X7R freedom is neuroinflammationMingqian Fang, Ren Lai · 2024 · Immunity
- Potential Benefits of Quercetin through P2X7 Modulation against Neuroinflammation in Alzheimer's DiseaseMatheus Chimelo Bianchini, Francini Franscescon, Adinei Abadio Soares, Vinicius Ansolin, Kailane Paula Pretto, Marcelo Lemos Vieira da Cunha, Débora Tavares de Resende e Silva · 2025 · Current Neuropharmacology
- New insights into pathogenisis and therapies of P2X7R in Parkinson’s diseaseShizhuang Wei, Xiaoyu Song, Yakui Mou, Ting Yang, Hanrui Wang, Hanrui Wang, Chao Ren, Xicheng Song · 2025 · npj Parkinson s Disease
- A Meta‐Analysis of the Effects of Chronic Stress on the Prefrontal Transcriptome in Animal Models and Convergence With Existing Human DataJinglin Xiong, Megan Hastings Hagenauer, Cosette A. Rhoads, Elizabeth I. Flandreau, Nancy Rempel-Clower, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Toni Q. Duan, Stanley J. Watson et al. · 2026 · Brain and Behavior
- Pathophysiology of COVID-19-Associated NeurotoxicityMarco Cascella, Elvio De Blasio · 2021 · Springer eBooks
- Tetracyclic 1,4-Naphthoquinone Thioglucoside Conjugate U-556 Blocks the Purinergic P2X7 Receptor in Macrophages and Exhibits Anti-Inflammatory Activity In VivoSergey Kozlovskiy, Еvgeny А. Pislyagin, Ekaterina S. Menchinskaya, Ekaterina A. Chingizova, Leonid A. Kaluzhskiy, Alexis S. Ivanov, Лихацкая Галина Николаевна, И. Г. Агафонова, Yuri E. Sabutski, Сергей Георгиевич Полоник et al. · 2023 · International Journal of Molecular Sciences
- Role of the P2 × 7 receptor in neurodegenerative diseases and its pharmacological propertiesZiyan Hu, Yifan Luo, Jinxi Zhu, Danling Jiang, Zhenzhong Luo, Lidong Wu, Li Jin, Shengliang Peng, Jialing Hu · 2023 · Cell & Bioscience
- Deficiency of purinergic P2X4 receptor alleviates experimental autoimmune hepatitis in miceZejin Liu, Mengyang Sun, Wenhua Liu, Fangyu Feng, Xinyu Li, Chaolei Jin, Yijie Zhang, Junpeng Wang · 2024 · Biochemical Pharmacology
- A patent review of P2X7 receptor antagonists to treat inflammatory diseases (2018–present)Jamshed Iqbal, Sehrish Bano, Imtiaz Ali Khan, Qing Huang · 2024 · Expert Opinion on Therapeutic Patents
- Molecular Characterization of Peritoneal Involvement in Primary Colon and Ovary Neoplasm: The Possible Clinical Meaning of the P2X7 Receptor-Inflammasome ComplexAnna Solini, Luigi Cobuccio, Chiara Rossi, Federico Parolini, Edoardo Biancalana, Stefania Cosio, Massimo Chiarugi, Angiolo Gadducci · 2021 · European Surgical Research
- Immune Response Studies Based on P2X7 Receptors: A Mini-ReviewYing Deng, Mengting Zhou, Xingtao Zhao, Xinyan Xue, Li Liao, Jing Wang, Yunxia Li · 2022 · Current Pharmaceutical Design
- Possible role of pannexin 1 channels and purinergic receptors in the pathogenesis and mechanism of action of SARS-CoV-2 and therapeutic potential of targeting them in COVID-19Zakiye Nadeali, Fatemeh Mohammad-Rezaei, Hamid Aria, Parvaneh Nikpour · 2022 · Life Sciences
- Humanized Mouse Model to Study the P2X7 Receptor in Graft-Versus-Host DiseaseDebbie Watson, Sam R Adhikary, Peter Cuthbertson, Nicholas J. Geraghty, Katrina M. Bird, Amal Elhage, Chloe Sligar, Ronald Sluyter · 2022 · Methods in molecular biology
- The Pannexin 1 Channel and the P2X7 Receptor Are in Complex Interplay to Regulate the Release of Soluble Ectonucleotidases in the Murine Bladder Lamina PropriaMafalda S. L. Aresta Branco, Alejandro Gutierrez Cruz, Lauren E. Peri, Violeta N. Mutafova–Yambolieva · 2023 · International Journal of Molecular Sciences
- Embers of the Past: Early Childhood Traumas Interact with Variation in P2RX7 Gene Implicated in Neuroinflammation on Markers of Current Suicide RiskZsüliet Kristóf, Zsófia Gál, Dóra Török, Nóra Eszlári, Sára Sütöri, Beáta Sperlágh, Ian Muir Anderson, J.F.W. Deakin, György Bagdy, Gabriella Juhász et al. · 2024 · International Journal of Molecular Sciences
- Targeting calciumopathy for neuroprotection: focus on calcium channels Cav1, Orai1 and P2X7Myriam Torres-Rico, Virginia García-Calvo, Adrián Gironda-Martínez, Jorge Pascual-Guerra, Antonio G. Garcı́a, Victoria Maneu · 2024 · Cell Calcium
- Chronic granulomatous disease: lessons in cell biology from monogenic immunodeficiencyPaige M Mortimer, Shuli Svetitsky, David Thomas · 2025 · Clinical & Experimental Immunology
- The NLRP3-P2X7 Axis and Cytokine Crosstalk in Alzheimer's Disease: Mechanisms, Implications, and Therapeutic OpportunitiesShubham Kurmi, Gaurav Doshi, Siddhi Bagwe Parab · 2025 · CNS & Neurological Disorders - Drug Targets
- Beyond Neuroinflammation: Microglia at the Crossroads of Amyloid, Tau, and Neurodegeneration in Alzheimer’s DiseaseRasoul Ebrahimi, Sanaz Bordbar, Ghazal Azad, Samin Davoody, MahSima Mahmoudi, Khadijeh Esmaeilpour · 2025 · Neurological Sciences
- The purinergic signalling and inflammation in the pathogenesis and progression of diabetes: key factors and therapeutic targetsAndré Campos de Lima, Lucas Macedo Chaves, Samantha Nuncio Prestes, Aline Mânica, Andréia Machado Cardoso · 2022 · Inflammation Research
- Role of purinergic receptors in cardiac sympathetic nerve injury in diabetes mellitus.Qi-Xing Hu, Gui-Lin Li · 2022 · Neuropharmacology
- Ginsenosides enhance P2X7-dependent cytokine secretion from LPS-primed rodent macrophagesKshitija Dhuna, R. M. Helliwell, Simone N. De Luca, Sarah J. Spencer, Leanne Stokes · 2023 · Purinergic Signalling
- Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndromeChuan Shen, Yongmei Jiang, Jia Lin, Yanglangxing He, Yue Liu, Dingzhi Fang · 2023 · Journal of Bioenergetics and Biomembranes
- LC-MS/MS analysis of Shenghui decoction component and its effect on learning and memory and neuroprotection in sleep deprivation model miceChun Wen, Ziheng Li, Cheng Li, Junzuo Zheng, Ping Wang, Linlin Chen, Qiuyun You, Li Ding · 2024 · Fitoterapia
- Damage-associated molecular patterns in viral infection: potential therapeutic targetsHuizhen Tian, Qiong Liu, Xiaomin Yu, Yanli Cao, Xiaotian Huang · 2024 · Critical Reviews in Microbiology
- P2X7 Purinoceptor Affects Ectopic Calcification of Dystrophic MusclesRobin M. H. Rumney, Justyna Róg, Natalia Chira, Alexander Peter Kao, Rasha Abd Ali Al-khalidi, Dariusz C. Górecki · 2022 · Frontiers in Pharmacology
- New insights into P2X7 receptor regulation: Ca2+-calmodulin and GDP bind to the soluble P2X7 ballast domainSimon Sander, Isabel Müller, María García-Alai, Annette Nicke, Henning Tidow · 2022 · Journal of Biological Chemistry
- Carboxyl terminus of Pannexin-1 plays a crucial role in P2X7 receptor-mediated signalingRutambhara Purohit, Amal Kanti Bera · 2023 · Biochemical and Biophysical Research Communications
- Natural phytochemicals as P2X7 receptor inhibitors for the treatment of inflammation-related diseasesQian Niu, Jincai Li, Meng Zhang, Peng Zhou · 2023 · Italian Journal of Food Science
- Genetic Polymorphisms of P2RX7 but Not of ADORA2A Are Associated with the Severity of SARS-CoV-2 InfectionJorge Lindo, Célia Nogueira, Rui Soares, Nuno Cunha, Maria Rosário Almeida, Lisa Rodrigues, PATRICIA MARGARIDA DOS SANTOS CARVALHEIRO COELHO, Francisco Rodrigues, Rodrigo Antunes Cunha, Teresa Gonçalves · 2024 · International Journal of Molecular Sciences
- P2X7 Receptor Indirectly Regulates the JAM-A Protein Content via Modulation of GSK-3βKarl-Philipp Wesslau, Anabel Stein, Michael Kasper, Kathrin Barth · 2019 · International Journal of Molecular Sciences
- Identify. Quantify. Predict. Why Immunologists Should Widely Use Molecular Imaging for Coronavirus Disease 2019Freimut D. Juengling, Antonio Maldonado, Frank R. Wuest, Thomas Hellmut Schindler · 2021 · Frontiers in Immunology
- Activation of the purinergic receptor P2X7 improves hepatosteatosis by promoting lipophagyZizhi Dong, Yujia Wei, Min Tao, Lili Zhang · 2021 · FEBS Letters
- Vitexin Alleviates Kainic Acid-Induced Seizure Through Inhibiting P2X7R/NLRP3 Signaling PathwayRu Chen, Si-Min Cheng, Hao-Chuan Wang, Kun-Dong, Huili Sun, Meng-Mei Sun, Bo Gao, Wen‐Ning Wu · 2025 · Inflammation
- Natural products target pyroptosis for ameliorating neuroinflammation: A novel antidepressant strategyGuangheng Zhang, Ruirui Shang, Xia Zhong, Shimeng Lv, Yunhao Yi, Yitong Lu, Zhiwei Xu, Yilin Wang, Jing Teng · 2025 · Phytomedicine
- Flow cytometry: An accurate tool for screening P2RX7 modulatorsAmélie Barczyk, Hélène Bauderlique‐Le Roy, Nathalie Jouy, Nicolas Renault, Audrey Hottin, Régis Millet, Valérie Vouret‐Craviari, Sahil Adriouch, Thierry Idziorek, Xavier Dezitter · 2020 · Cytometry Part A
- P2X7 receptor as a potential therapeutic target for perinatal brain injury associated with preterm birthEmily Zucker, Irina D. Burd · 2022 · Experimental Neurology
- Abacavir causes leukocyte/platelet crosstalk by activating neutrophil P2X7 receptors thus releasing soluble lectin‐like oxidized low‐density lipoprotein receptor‐1María Amparo Blanch‐Ruiz, Ainhoa Sánchez‐López, César Ríos‐Navarro, Raquel Ortega‐Luna, Víctor Collado‐Díaz, Samuel Orden, María Ángeles Martínez-Cuesta, Juan Vicente Esplugues, Ángeles Álvarez · 2022 · British Journal of Pharmacology
- Purinergic P2X7R as a potential target for pancreatic cancerQingqing Yu, Xin Wang, Xinyu Li, Xue Bai, Ronglan Zhao, Xiaoxiang Peng · 2023 · Clinical & Translational Oncology
- Thymoquinone, a Novel Multi-Strike Inhibitor of Pro-Tumorigenic Breast Cancer (BC) Markers: CALR, NLRP3 Pathway and sPD-L1 in PBMCs of HR+ and TNBC PatientsSawsan Elgohary, Reda A. Eissa, Hend Mohamed El Tayebi · 2023 · International Journal of Molecular Sciences
- Self-DNA driven inflammation in COVID-19 and after mRNA-based vaccination: lessons for non-COVID-19 pathologiesMartin Heil · 2024 · Frontiers in Immunology
- Regulation of the Acute Sickness Response by the P2RX7 ReceptorHui Li, Erin Cvejic, Ben J. Gu, Ute S. Vollmer-Conna, Ian Bernard Hickie, Denis Wakefield, Tracey A Davenport, James S. Wiley, Andrew R. Lloyd · 2021 · The Journal of Infectious Diseases
- Pannexin channel 1, P2×7 receptors, and Dimethyl Sulfoxide mediate pain responses in zebrafishDarlan Gusso, Fernanda Fernandes Cruz, Pâmella Moreira Fritsch, Marília Oberto da Silva Gobbo, Fernanda Bueno Morrone, Carla Denise Bonan · 2022 · Behavioural Brain Research
- ZoomForward2022: European Congress on ObesityJørgensen, Rasmus Møller, Bøttger, B., Esben Thyssen Vestergaard, Kremke, Britta, Bahnsen, Rikke Frederiksen, Bent Windelborg Nielsen, Jens Meldgaard Bruun · 2022 · Obesity Facts
- Islet regeneration protein Reg3g promotes macrophage clearance of β cell-derived dysfunctional mitochondria-rich vesicles to mitigate T2DMSenlin Li, Mengheng Wang, Hong Zhou, Jia Liu, Mengxuan Wang, Huimin Yuan, Mengzhu Zheng, Xin Li, Xiangling Zhu, Ming Xiang · 2025 · Redox Biology
- Electroacupuncture reduces microglial pyroptosis via P2X7R/NLRP3 axis in the rat model of asphyxial cardiac arrest and cardiopulmonary resuscitationYu-Ting Yan, Fei Guo, Yong-fei Liu, Zhaoyan Zhao, Xude Sun, Changjun Gao · 2025 · Neuroscience
- Matrix metalloproteinases, purinergic signaling, and epigenetics: hubs in the spinal neuroglial network following peripheral nerve injuryCiro De Luca, Assunta Virtuoso, Michele Cerasuolo, Francesca Gargano, Anna Maria Colangelo, Marialuisa Lavitrano, Giovanni Cirillo, Michèle Papa · 2022 · Histochemistry and Cell Biology
- Differential Immunomodulatory Effects of Head and Neck Cancer-Derived Exosomes on B Cells in the Presence of ATPMali Coray, Veronika Göldi, Lukas Schmid, Laura Benecke, Fabrício Figueiró, Laurent Müller · 2022 · International Journal of Molecular Sciences
- Pharmacological interaction and immune response of purinergic receptors in therapeutic modulationSeyed Hossein Kiaie, Zahra Hatami, Mohammad Sadegh Nasr, Pouya Pazooki, Salar Hemmati, Behzad Baradaran, Hadi Valizadeh · 2023 · Purinergic Signalling
- How is the P2X7 receptor signaling pathway involved in epileptogenesis?Caichuan Wei, Miaoying Fu, Haiju Zhang, Baozhen Yao · 2024 · Neurochemistry International
- Transcriptional Immune Signatures of Alveolar Macrophages and the Impact of the NLRP3 Inflammasome on Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) ReplicationJulie A. Hicks, Dongwan Yoo, Hsiao‐Ching Liu · 2020 · Viruses
- Abacavir Increases Purinergic P2X7 Receptor Activation by ATP: Does a Pro-inflammatory Synergism Underlie Its Cardiovascular Toxicity?Víctor Collado‐Díaz, María Ángeles Martínez-Cuesta, María Amparo Blanch‐Ruiz, Ainhoa Sánchez‐López, Patricia García-Martínez, José‐Esteban Peris, Iris Usach, Maria Dolores Ivorra, Alessandra Lacetera, Sonsoles Martín‐Santamaría et al. · 2021 · Frontiers in Pharmacology
- P2X7 polymorphism (rs3751143) and its reliability as a diagnostic biomarker for tuberculosis: A systematic review and meta-analysisMasoud Keikha, Mohsen Karbalaei · 2021 · Indian Journal of Tuberculosis
- Soluble P2X7 Receptor Plasma Levels in Obese Subjects before and after Weight Loss via Bariatric SurgeryAngelo Di Vincenzo, Marnie Granzotto, Andrea Graziani, Marika Crescenzi, Mirto Foletto M. D, Luca Prevedello, Federico Capone, Roberto Vettor, Marco Rossato · 2023 · International Journal of Molecular Sciences
- Development, validation and implementation of radio-HPLC methods for the P2X7-receptor-targeted [11C]GSK1482160 radiopharmaceuticalCarmen L. Wissmann, Min Wang, Mingzhang Gao, Qi‐Huang Zheng, Mark A. Green · 2018 · Applied Radiation and Isotopes
- Extracellular Vesicles Associated Metabolites as Intercellular Signalling Mediators in Disease and TherapyABDUL QADEER, Abd Ullah, Muhammad Zahoor Khan, Khalaf F. Alsharif, Fuad M. Alzahrani, Khalid J. Alzahrani, Abdulwahab Abuderman · 2026 · Metabolites
- Establishment and behavioural characterization of a novel constitutive P2X7 receptor knockout mouse lineIven-Alex von Mücke-Heim, Judit Oldekamp, Michael W. Metzger, Sarah Kläffgen, Hao Tang, Sandra M. Walser, Nina Dedic, Gerhard Rammes, Florian Holsboer, Wolfgang Wurst et al. · 2025 · Purinergic Signalling
- P2X7 receptor antagonism suppresses epileptiform‐like activity in an inflammation‐primed human iPSC‐derived neuron model of drug‐resistant epilepsyJaideep Kesavan, Yitao Wang, Klaus Dinkel, Michael Hamacher, Jochen H.M. Prehn, David Clifford Henshall, Tobías Engel · 2025 · British Journal of Pharmacology
- Advances in how the peripheral immune system interacts with the brain in health and diseaseVictor Manuel Ruiz-Rodríguez, Ares Orlando Cuellar-Santoyo, Ana María Estrada‐Sánchez · 2025 · Neuroscience
- P2X receptors in GtoPdb v.2023.1Francesco Di Virgilio, Simonetta Falzoni, Anna Fortuny‐Gomez, Samuel J. Fountain, Michael F. Jarvis, Charles Kennedy, Brian F. King, Jessica Meades, Annette Nicke, John A. Peters · 2023 · IUPHAR/BPS Guide to Pharmacology CITE
- Targeting 7KCh-Induced Cell Death Response Mediated by p38, P2X7 and GSDME in Retinal Pigment Epithelium Cells with Sterculic AcidAna Pariente, Rafael Peláez, Rodrigo Ochoa, Álvaro Pérez-Sala, Ángela Villanueva-Martínez, María Bobadilla, Ignacio M. Larráyoz · 2023 · Pharmaceutics
- P2X7 receptors: a bibliometric review from 2002 to 2023Haiting Tang, Wei Wei, Yu Luo, Xiaoqing Lu, Jun Chen, Shenqiao Yang, Fei Wu, Haiyan Zhou, Wenbin Ma, Xin Yang · 2024 · Purinergic Signalling
- P2X7 regulates ependymo-radial glial cell proliferation in adult Danio rerio following spinal cord injuryEva E. Stefanova, Julian Vincent T. Dychiao, Mavis C. Chinn, Matin Borhani, Angela L. M. Scott · 2024 · Biology Open
- Prolonged intermittent theta burst stimulation restores the balance between A2AR- and A1R-mediated adenosine signaling in the 6-hydroxidopamine model of Parkinson’s diseaseMilica Zeljković, Jelena Stanojevic, Ivana D. Stevanović, Milica Ninković, Tihomir V Ilic, Nadežda Nedeljković, Milorad Dragić · 2024 · Neural Regeneration Research
- Role of purinoreceptors in the release of extracellular vesicles and consequences on immune response and cancer progressionThomas Duret, Mohammed I. Y. Elmallah, Jérôme Rollin, Philippe Gatault, Lin‐Hua Jiang, Sébastien Roger · 2024 · Biomedical Journal
- Exploring the mechanism by which acupuncture and moxibustion reduce colonic mucosal inflammation in rats with ulcerative colitis (UC) based on the P2X7R-NLRP3 inflammasome pathwayZhenzhen Fang, Huangan Wu, Luyi Wu, Yanan Liu, Ling Yang, Chen Zhao, Zhe Ma, Yan Huang, Wenjia Wang · 2023 · Journal of Acupuncture and Tuina Science
- Tissue- and temporal-specific roles of extracellular ATP on T cell metabolism and functionIgor Santiago-Carvalho, Alma Banuelos, Henrique Borges da Silva · 2023 · Immunometabolism
- [Diagnostic value of P2X7 receptor and its role in inflammatory reaction in rheumatoid arthritis].Yonghe Chen, Baochang Su, Mengqiao Shang · 2018 · Europe PMC (PubMed Central)
- Myeloid-derived β-hexosaminidase is essential for neuronal health and lysosome function: implications for Sandhoff diseaseKate Inman Tsourmas, Claire Ann Butler, Nellie E. Kwang, Zachary R. Sloane, Koby J. G. Dykman, Ghassan O. Maloof, Christiana A. Prekopa, Robert P. Krattli, Sanad M. El-Khatib, Vivek Swarup et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- The Double‐Edged Sword: The Complex Function of Enteric Glial Cells in Neurodegenerative DiseasesIngrid Prata Mendonça, Christina Alves Peixoto · 2025 · Journal of Neurochemistry
- Purα overexpression mitigates neonatal hypoxic-ischemic brain damage by inhibiting neuronal pyroptosis via the P2X7R/NLRP3/Caspase-1 pathwayDa Zheng, Hui Zhang, Yi-Kai Zou, Jiao-Yang Yang, Shuyi He, Hai-jing Peng, Jianxia Liu, Shao-Hua Qi, Jia‐Wei Min · 2026 · Brain Research Bulletin
- P2X7 receptors as targets for neuroprotectionVictoria Maneu, Antonio G. García · 2026 · Neuropharmacology
- Mass Cytometry Reveals Comparable Proportions of Leukocyte Subsets and Cell Surface P2X7 or CD39 on Human Peripheral Blood Mononuclear Cell Samples Isolated by Ficoll-Paque or SepMate Tube Density Gradient CentrifugationAmal Elhage, Bavani Gunasegaran, Natalie J. Smith, Ross J. Turner, Debbie Watson, Helen Marie McGuire, Ronald Sluyter · 2026 · Cells
- Role of Oxysterols in Ocular Degeneration Mechanisms and Involvement of P2X7 ReceptorElodie Olivier, Patrice Rat · 2023 · Advances in experimental medicine and biology
- Antifibrotic effect of the P2X7 receptor antagonist A740003 against acute myocardial infarction-induced fibrotic remodellingNoura Almusallam, Asma S. Alonazi, Anfal F. Bin Dayel, Abdullah Almubarak, Rizwan Ali, Wajd Althakfi, Rehab Ali, Nouf Mohamed Al-Rasheed · 2024 · Saudi Pharmaceutical Journal
- Enhanced exosome secretion regulated by microglial P2X7R in the medullary dorsal horn contributes to pulpitis-induced painJing Zhang, Zhuo You Yu, Mingjun Wang, Xiaoning Kang, Xiaoke Wu, Fengjiao Yang, Lu Yang, Shukai Sun, Li-an Wu · 2025 · Cell & Bioscience
- CTSO and HLA-DQA1 as biomarkers in sepsis-associated ARDS: insights from RNA sequencing and immune infiltration analysisYi Shen, Yi Yao, Li Hai, Yang Li, Ying Chun Hu · 2025 · BMC Infectious Diseases
- P2X7 receptor as a key player in pathological pain: insights into Neuropathic, inflammatory, and cancer painPan Hong Jiang, Cai Wang, Fajing Jia, Hua Wu, Haihu Hao, Shaoze Jing · 2025 · Frontiers in Pharmacology