The P2X7 receptor: A main player in inflammation

Adinolfi, Elena, Giuliani, Anna Lisa, De Marchi, Elena, Pegoraro, Anna, Orioli, Elisa, Di Virgilio, Francesco·2018·Biochemical Pharmacology

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  10. Metformin alleviates hydrogen peroxide–induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons
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  11. Amphiphilic anti-SARS-CoV-2 drug remdesivir incorporates into the lipid bilayer and nerve terminal membranes influencing excitatory and inhibitory neurotransmission
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  12. Pannexin 3 activates P2X7 receptor to mediate inflammation and cartilage matrix degradation in temporomandibular joint osteoarthritis
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  17. P2X7 receptor deficiency attenuates cisplatin-induced kidney injury via inhibiting NLRP3 inflammasome activation
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  18. Association of Hypomorphic P2X7 Receptor Genotype With Age
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  19. Use of Humanized Mouse Models to Investigate the Roles of Purinergic Signaling in Inflammation and Immunity
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  20. Betulin Targets Lipin1/2-Meidated P2X7 Receptor as a Therapeutic Approach to Attenuate Lipid Accumulation and Metaflammation
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  37. Embers of the Past: Early Childhood Traumas Interact with Variation in P2RX7 Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk
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  41. Beyond Neuroinflammation: Microglia at the Crossroads of Amyloid, Tau, and Neurodegeneration in Alzheimer’s Disease
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  43. Role of purinergic receptors in cardiac sympathetic nerve injury in diabetes mellitus.
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  45. Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndrome
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  53. P2X7 Receptor Indirectly Regulates the JAM-A Protein Content via Modulation of GSK-3β
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  55. Activation of the purinergic receptor P2X7 improves hepatosteatosis by promoting lipophagy
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