Spaced initial stimulus familiarization enhances novelty preference in Long-Evans rats
Abstract
Berlyne [Berlyne, D.E., 1950. Novelty and curiosity as determinants of exploratory behaviour. Brit. J. Psychol. 41, 68-80] first illustrated that rats prefer to explore novel objects over ones with which they have had previous experience. Recently, variants on this novel object recognition (NOR) task have become widely popular and have been employed in numerous neuroscience and behavioral pharmacological studies investigating memory processes. Given this popularity, a thorough understanding of the various behavioral processes involved in novelty reaction and preference is essential. The current study compared the effects of spaced and massed initial stimulus exposures upon later object exploration and novel stimulus preference in Long-Evans rats. Results illustrated that a distributed initial stimulus familiarization procedure promoted greater novel object preference than did a massed procedure, and suggest that the novel object recognition task is sensitive to spacing effects in a similar fashion to more traditional learning paradigms. The mechanisms underlying such spacing effects are briefly discussed.
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LTP has a previously undetected refractory period, lasting for 30-60 min, which creates an analog of the behavioral spaced trials effect.
“In all, the present results show that LTP has a previously undetected refractory period, lasting for 30–60 min, which creates an analog of the behavioral spaced trials effect (13).”
From Synaptic evidence for the efficacy of spaced learning (2012) · cites this paper as [13]
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- Authors
- Anderson, M. J., Jablonski, S. A., & Klimas, D. B.
- Affiliations
- Saint Joseph's University (US)
- Corresponding author
- Anderson, Matthew J.
- Venue
- Behavioural Processes
- Publisher
- Elsevier BV
- Published
- 2008-07
- Volume
- 78
- Issue
- 3
- Pages
- 481-486
- ISSN
- 0376-6357 (ISSN-L)
- OpenAlex
- W2138817069
- Cited by
- 30
- References
- 29
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 5 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 4 · 2013: 3 · 2012: 2
- FWCI
- 0.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioural Processes (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Psychological and Educational Research Studies
- Keywords
- novel object recognition, novelty preference, spacing effect, memory, exploratory behavior, Long-Evans rats
- MeSH terms
- Animals, Behavior, Animal, Exploratory Behavior, Habituation, Psychophysiologic, Male, Memory, Spatial Behavior, Rats, Long-Evans, Recognition, Psychology, Rats
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