The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Silk film biomaterials for cornea tissue engineering
Open accessAbstract
Biomaterials for corneal tissue engineering must demonstrate several critical features for potential utility in vivo, including transparency, mechanical integrity, biocompatibility and slow biodegradation. Silk film biomaterials were designed and characterized to meet these functional requirements. Silk protein films were used in a biomimetic approach to replicate corneal stromal tissue architecture. The films were 2 μm thick to emulate corneal collagen lamellae dimensions, and were surface patterned to guide cell alignment. To enhance trans-lamellar diffusion of nutrients and to promote cell-cell interaction, pores with 0.5 to 5.0 μm diameters were introduced into the silk films. Human and rabbit corneal fibroblast proliferation, alignment and corneal extracellular matrix expression on these films in both 2D and 3D cultures was demonstrated. The mechanical properties, optical clarity and surface patterned features of these films, combined with their ability to support corneal cell functions suggest this new biomaterial system offers important potential benefits for corneal tissue regeneration.
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Cites
Myofibroblasts and mechano-regulation of connective tissue remodelling
Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., & Brown, R. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm809 · Cited by 4,290
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Silk fibroin biomaterials for tissue regenerations
Kundu, B., Rajkhowa, R., Kundu, S. C., & Wang, X. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.043 · Cited by 1,391
Structures, mechanical properties and applications of silk fibroin materials
Koh, L.-D., Cheng, Y., Teng, C.-P., Khin, Y.-W., Loh, X.-J., Tee, S.-Y., Low, M., Ye, E., Yu, H.-D., Zhang, Y.-W., et al. (2015) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2015.02.001 · Cited by 1,241
Elastomeric biomaterials for tissue engineering
Chen, Q., Liang, S., & Thouas, G. A. (2013) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.05.003 · Cited by 564
Design, clinical translation and immunological response of biomaterials in regenerative medicine
Sadtler, K., Singh, A., Wolf, M. T., Wang, X., Pardoll, D. M., & Elisseeff, J. H. (2016) · Nature Reviews Materials · doi:10.1038/natrevmats.2016.40 · Cited by 319
Organ-on-a-chip platforms: a convergence of advanced materials, cells, and microscale technologies
Ahadian, S., Civitarese, R., Bannerman, D., Mohammadi, M. H., Lu, R., Wang, E., Davenport‐Huyer, L., Lai, B., Zhang, B., Zhao, Y., et al. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201700506 · Cited by 315
Metadata
- Authors
- Lawrence, B. D., Marchant, J. K., Pindrus, M. A., Omenetto, F. G., & Kaplan, D. L.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2009-03
- Volume
- 30
- Issue
- 7
- Pages
- 1299-1308
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2029167744
- Cited by
- 412
- References
- 1
- FWCI
- 7.18
- Type
- journal article
- Language
- en
- Open access
- green
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- Lawrence, B. D., Marchant, J. K., Pindrus, M. A., Omenetto, F. G., & Kaplan, D. L. (2009). Silk film biomaterials for cornea tissue engineering. Biomaterials. https://doi.org/10.1016/j.biomaterials.2008.11.018
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