The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Functionalizable and ultra stable nanoparticles coated with zwitterionic poly(carboxybetaine) in undiluted blood serum
Abstract
A new surface chemistry presenting an abundance of functional groups for ligand immobilization in an ultra-low fouling background all in one material for nanoparticles was introduced. This surface platform, as demonstrated by zwitterionic poly(carboxybetaine acrylamide) (polyCBAA) coated nanoparticles, is not only ultra stable in undiluted human blood serum, but also can be conjugated to biomolecules conveniently and effectively. Thus, this surface chemistry is ideal to create multi-functional nanoparticles for targeted delivery and diagnostics. In addition, this work clearly shows that 10% blood serum commonly used to evaluate the stability of nanoparticles is insufficient and a new evaluation criterion with undiluted blood serum is recommended.
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Cites
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A Survey of Structure−Property Relationships of Surfaces that Resist the Adsorption of Protein
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Cited by
Jiang, S., & Cao, Z. (2010) · Advanced Materials · doi:10.1002/adma.200901407 · Cited by 2,027
Self-citationBlock copolymer micelles in nanomedicine applications
Cabral, H., Miyata, K., Osada, K., & Kataoka, K. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00199 · Cited by 1,309
Duan, X., & Li, Y. (2013) · Small · doi:10.1002/smll.201201390 · Cited by 926
Hoang Thi, T. T., Pilkington, E. H., Nguyen, D. H., Lee, J. S., Park, K. D., & Truong, N. P. (2020) · Polymers · doi:10.3390/polym12020298 · Cited by 668
Surface Functionalization of Gold Nanoparticles with Red Blood Cell Membranes
Gao, W., Hu, C. J., Fang, R. H., Luk, B. T., Su, J., & Zhang, L. (2013) · Advanced Materials · doi:10.1002/adma.201300638 · Cited by 465
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Metadata
- Authors
- Yang, W., Zhang, L., Wang, S., White, A. D., & Jiang, S.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2009-10
- Volume
- 30
- Issue
- 29
- Pages
- 5617-5621
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2019943506
- Cited by
- 242
- References
- 3
- FWCI
- 7.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yang, W., Zhang, L., Wang, S., White, A. D., & Jiang, S. (2009). Functionalizable and ultra stable nanoparticles coated with zwitterionic poly(carboxybetaine) in undiluted blood serum. Biomaterials. https://doi.org/10.1016/j.biomaterials.2009.06.036
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