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Cited by 963

The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.

The role of m6A RNA methylation in cancer

Open access
Sun, Ting, Wu, Ruiyan, Ming, Liang·2019·Biomedicine & Pharmacotherapy

Abstract

N6-methyladenosine (m6A), the most abundant internal modification of RNA in eukaryotic cells, has gained increasing attention in recent years. The m6A modification affects multiple aspects of RNA metabolism, ranging from RNA processing, nuclear export, RNA translation to decay. Emerging evidence suggests that m6A methylation plays a critical role in cancer through various mechanisms. Moreover, m6A methylation has provided more possibilities for the early diagnosis and treatment of cancers. In this review, we focus on m6A-associated mechanisms and functions in several major malignancies and summarize the dual role of m6A methylation as well as its prospects in cancer.

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Metadata

Authors
Sun, T., Wu, R., & Ming, L.
Venue
Biomedicine & Pharmacotherapy
Publisher
Elsevier BV
Published
2019-04
Volume
112
Pages
108613
ISSN
0753-3322 (ISSN-L)
OpenAlex
W2915777758
Cited by
963
References
108
FWCI
31.94
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The role of m6A RNA methylation in cancer. https://app.cochat.ai/papers/10.1016/j.biopha.2019.108613
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Sun, T., Wu, R., & Ming, L. (2019). The role of m6A RNA methylation in cancer. Biomedicine & Pharmacotherapy. https://doi.org/10.1016/j.biopha.2019.108613

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.