The DOI matches its Crossref record; 159 of the 159 references it cites were found in a registry or an index.
Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing
Open accessAbstract
Wound management in diabetic patient is of an extreme clinical and social concern. The delayed and impaired healing makes it more critical for research focus. The research on impaired healing process is proceeding hastily evident by new therapeutic approaches other than conventional such as single growth factor, dual growth factor, skin substitutes, cytokine stimulators, cytokine inhibitors, matrix metalloproteinase inhibitors, gene and stem cell therapy, extracellular matrix and angiogenesis stimulators. Although numerous studies are available that support delayed wound healing in diabetes but detailed mechanistic insight including factors involved and their role still needs to be revealed. This review mainly focuses on the molecular cascades of cytokines (with growth factors) and erstwhile factors responsible for delayed wound healing, molecular targets and recent advancements in complete healing and its cure. Present article briefed recent pioneering information on possible molecular targets and treatment strategies including clinical trials to clinicians and researchers working in similar area.
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1 retracted
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RetractedThe Pathobiology of Diabetic Complications
Brownlee, M. (2005) · Diabetes · doi:10.2337/diabetes.54.6.1615 · Cited by 5,339
PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing
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Cellular and molecular basis of wound healing in diabetes
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Cited by
Zhu, Y., Zhang, J., Song, J., Yang, J., Du, Z., Zhao, W., Guo, H., Wen, C., Li, Q., Sui, X., et al. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201905493 · Cited by 538
Biofilm and wound healing: from bench to bedside
Goswami, A. G., Basu, S., Banerjee, T., & Shukla, V. K. (2023) · European Journal of Medical Research · doi:10.1186/s40001-023-01121-7 · Cited by 178
Cai, Y., Chen, K., Liu, C., & Qu, X. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.04.019 · Cited by 112
Chlorella sp.-Ameliorated Undesirable Microenvironment Promotes Diabetic Wound Healing
Wu, H., Yang, P., Li, A., Jin, X., Zhang, Z., & Lv, H. (2023) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.06.012 · Cited by 65
Functional molecule-mediated assembled copper nanozymes for diabetic wound healing
Huang, W., Xu, P., Fu, X., Yang, J., Jing, W., Cai, Y., Zhou, Y., Tao, R., & Yang, Z. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-02048-1 · Cited by 47
Metadata
- Authors
- Patel, S., Srivastava, S., Singh, M. R., & Singh, D.
- Venue
- Biomedicine & Pharmacotherapy
- Publisher
- Elsevier BV
- Published
- 2019-04
- Volume
- 112
- Pages
- 108615
- ISSN
- 0753-3322 (ISSN-L)
- OpenAlex
- W2915171406
- Cited by
- 1,049
- References
- 159
- FWCI
- 50.94
- Type
- journal article
- Language
- en
- Open access
- gold
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- Patel, S., Srivastava, S., Singh, M. R., & Singh, D. (2019). Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing. Biomedicine & Pharmacotherapy. https://doi.org/10.1016/j.biopha.2019.108615
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
