The DOI matches its Crossref record; 210 of the 213 references it cites were found in a registry or an index.
Recent progress in tannic acid based approaches as a natural polyphenolic biomaterial for cancer therapy: A review
Open accessAbstract
Significant advancements have been noticed in cancer therapy for decades. Despite this, there are still many critical challenges ahead, including multidrug resistance, drug instability, and side effects. To overcome obstacles of these problems, various types of materials in biomedical research have been explored. Chief among them, the applications of natural compounds have grown rapidly due to their superb biological activities. Natural compounds, especially polyphenolic compounds, play a positive and great role in cancer therapy. Tannic acid (TA), one of the most famous polyphenols, has attracted widespread attention in the field of cancer treatment with unique structural, physicochemical, pharmaceutical, anticancer, antiviral, antioxidant and other strong biological features. This review concentrated on the basic structure along with the important role of TA in tuning oncological signal pathways firstly, and then focused on the use of TA in chemotherapy and preparation of delivery systems including nanoparticles and hydrogels for cancer therapy. Besides, the application of TA/Fe3+ complex coating in photothermal therapy, chemodynamic therapy, combined therapy and theranostics is discussed.
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“Tannic acid (TA), a natural polyphenolic compound, has attracted significant attention in the biomedical field due to its potent antioxidant and anti-inflammatory properties24,25, indicating its potential for application in the treatment of osteoporotic fractures.”
From Intelligence-responsive wettability switch coating on magnesium implants for treating osteoporotic fracture (2026) · cites this paper as [24]
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Items 201–210 of 210
A versatile platform of magnetic microspheres loaded with dual-anticancer drugs for drug release
Wang, X., Jing, X., Zhang, X., Liu, Q., Liu, J., Song, D., Wang, J., & Liu, L. (2016) · Materials Chemistry and Physics · doi:10.1016/j.matchemphys.2016.04.021 · Cited by 15
pH-Sensitive Dairy-Derived Hydrogels with a Prolonged Drug Release Profile for Cancer Treatment
Mayorova, O. A., Jolly, B. C. N., Verkhovskii, R. A., Plastun, V. O., Sindeeva, O. A., & Douglas, T. (2021) · Materials · doi:10.3390/ma14040749 · Cited by 15
Yin, S., Hu, Y., Zheng, J., Li, J., & Yang, R. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c15205 · Cited by 13
Knowledge Level of Working and Student Nurses on Cervical Cancer and Human Papilloma Virus Vaccines
Topan, A. K., Öztürk, Ö. A., Eroglu, H., Bahadır, Ö., Harma, M., & Harma, M. I. (2015) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2015.16.6.2515 · Cited by 12
MRI contrast enhancement of liver pre-neoplasia using iron–tannic nanoparticles
Phatruengdet, T., Intakhad, J., Tapunya, M., Chariyakornkul, A., Hlaing, C. B., Wongpoomchai, R., & Pilapong, C. (2020) · RSC Advances · doi:10.1039/d0ra07308c · Cited by 10
Phatruengdet, T., Khuemjun, P., Intakhad, J., Krunchanuchat, S., Chariyakornkul, A., Wongpoomchai, R., & Pilapong, C. (2021) · Nanotheranostics · doi:10.7150/ntno.63310 · Cited by 8
Design and synthesis of multi-targeted nanoparticles for gene delivery to breast cancer tissues
Afrouz, M., Amani, A., Eftekhari, A., Coudret, C., Elias, S. G., Ahmadian, Z., & Alebrahim, M. T. (2022) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-022-02303-6 · Cited by 8
Self-citationAhmadian, Z., Correia, A., Hasany, M., Figueiredo, P., Dobakhti, F., Eskandari, M. R., Hosseini, S. H., Abiri, R., Khorshid, S., Hirvonen, J. J., et al. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202170009 · Cited by 7
Self-citationAhmadian, Z., Dargahi, A. R., Musaie, K., & Eskandari, M. R. (2021) · Pharmaceutical Sciences · doi:10.34172/ps.2021.65 · Cited by 6
Self-citationPaleogeographic Reconstruction of Northern Caribbean Region from Late Cretaceous to Recent
Ahmad, S., & Escalona, A. (2014) · Proceedings · doi:10.3997/2214-4609.20141659 · Cited by 2
Research works printed but not linked: 4
- Kazeminava, 2023, Crosslinking Chitosan with Silver-Sulfur Doped Graphene Quantum Dots: an Effictive Antibacterial Nanocomposite Hydrogel Films, J. Polym. Environ., 12
- Shah, 2012, Synthesis, characterization and applications of bimetallic (Au-Ag, Au-Pt, Au-Ru) alloy nanoparticles, Rev. Adv. Mater. Sci., 30, 133
- Pylak-Piwko, 2017, Side effects of drugs used in cancer chemotherapy, Journal of Education, Health Sport, 7, 1434
- Zhou, 2008, Compact fuzzy rules induction and feature extraction using SVM with particle swarms for breast cancer treatments, 2008 IEEE Congress on Evolutionary Computation (IEEE World Congress on, Comput. Intell., 1469
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Hosseini, M., Moghaddam, L., Barner, L., Cometta, S., Hutmacher, D. W., & Savi, F. M. (2024) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2024.101908 · Cited by 189
Zeng, Y., Mao, S., Huang, B., Ye, X., & Tian, J. (2024) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2024.110333 · Cited by 44
Zuo, Y., Zhu, F., Jiang, S., Sui, Z., & Kong, X. (2024) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2024.110419 · Cited by 30
Cheng, S., Wu, C.-H., Tsai, Y., Song, J., Chen, H.-M., Yeh, T., Shen, C.-T., Chiang, J.-C., Lee, H.-M., Huang, K., et al. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.01.066 · Cited by 29
Chen, Y., Lin, Y., Liu, Z., Zhang, Y., Hu, Z., Ai, M., Shen, Y., Lian, D., Wang, C., Liu, X., et al. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.101856 · Cited by 28
Metadata
- Authors
- Ghasemian, M., Kazeminava, F., Naseri, A., Mohebzadeh, S., Abbaszadeh, M., Kafil, H. S., & Ahmadian, Z.
- Affiliations
- Lorestan University of Medical Sciences (IR)
- Tabriz University of Medical Sciences (IR)
- University of Mohaghegh Ardabili (IR)
- Corresponding author
- Kafil, Hossein Samadi
- Ahmadian, Zainab
- Venue
- Biomedicine & Pharmacotherapy
- Publisher
- Elsevier BV
- Published
- 2023-10
- Volume
- 166
- Pages
- 115328
- ISSN
- 0753-3322 (ISSN-L)
- OpenAlex
- W4385847696
- Cited by
- 55
- References
- 213
- Citations by year
- 2026: 13 · 2025: 26 · 2024: 15 · 2023: 1
- FWCI
- 1.23
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Biomedicine & Pharmacotherapy (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Lorestan University of Medical Sciences
- Tabriz University of Medical Sciences
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Physical Sciences › Chemistry › Organic Chemistry › Tannin, Tannase and Anticancer Activities
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Keywords
- tannic acid, polyphenols, cancer therapy, anticancer activity, chemotherapy, drug delivery systems, nanoparticles, hydrogels, photothermal therapy, chemodynamic therapy, Fe3+ complexes, theranostics, multidrug resistance
- MeSH terms
- Biocompatible Materials, Humans, Neoplasms, Tannins, Polyphenols
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