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Cited by 462

The DOI matches its Crossref record; 237 of the 237 references it cites were found in a registry or an index.

Advances and challenges in the treatment of lung cancer

Open access
Li, Yuting, Yan, Bingshuo, He, Shiming·2023·Biomedicine & Pharmacotherapy

Abstract

Lung cancer accounts for a relatively high proportion of malignant tumors. As the most prevalent type of lung cancer, non-small cell lung cancer (NSCLC) is characterized by high morbidity and mortality. Presently, the arsenal of treatment strategies encompasses surgical resection, chemotherapy, targeted therapy and radiotherapy. However, despite these options, the prognosis remains distressingly poor with a low 5-year survival rate. Therefore, it is urgent to pursue a paradigm shift in treatment methodologies. In recent years, the advent of sophisticated biotechnologies and interdisciplinary integration has provided innovative approaches for the treatment of lung cancer. This article reviews the cutting-edge developments in the nano drug delivery system, molecular targeted treatment system, photothermal treatment strategy, and immunotherapy for lung cancer. Overall, by systematically summarizing and critically analyzing the latest progress and current challenges in these treatment strategies of lung cancer, we aim to provide a theoretical basis for the development of novel drugs for lung cancer treatment, and thus improve the therapeutic outcomes for lung cancer patients.

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Metadata

Authors
Li, Y., Yan, B., & He, S.
Venue
Biomedicine & Pharmacotherapy
Publisher
Elsevier BV
Published
2023-12
Volume
169
Pages
115891
ISSN
0753-3322 (ISSN-L)
OpenAlex
W4388742731
Cited by
462
References
237
FWCI
73.23
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Advances and challenges in the treatment of lung cancer. https://app.cochat.ai/papers/10.1016/j.biopha.2023.115891
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Li, Y., Yan, B., & He, S. (2023). Advances and challenges in the treatment of lung cancer. Biomedicine & Pharmacotherapy. https://doi.org/10.1016/j.biopha.2023.115891

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.