Fear and anxiety take a double hit from vagal nerve stimulation
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Rodent models of PTSD treated with extinction learning and VNS have yielded very encouraging results.
“Rodent models of PTSD treated with extinction learning and VNS have yielded very encouraging results (Fanselow, 2013; Peña et al., 2013).”
From Maladaptive autonomic regulation in PTSD accelerates physiological aging (2015) · cites this paper as Fanselow, 2013
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Extinction-Reconsolidation Boundaries: Key to Persistent Attenuation of Fear Memories
Monfils, M.-H., Cowansage, K. K., Klann, E., & LeDoux, J. E. (2009) · Science · doi:10.1126/science.1167975 · Cited by 960 · see citing works
Adrenergic transmission facilitates extinction of conditional fear in mice
Cain, C. K., Blouin, A. M., & Barad, M. (2004) · Learning & Memory · doi:10.1101/lm.71504 · Cited by 215 · see citing works
Woods, A. M., & Bouton, M. E. (2006) · Behavioral Neuroscience · doi:10.1037/0735-7044.120.5.1159 · Cited by 133 · see citing works
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Research works printed but not linked: 7
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Brain-heart interaction in perseverative cognition
Ottaviani, C. (2018) · Psychophysiology · doi:10.1111/psyp.13082 · Cited by 129 · see citing works
Maladaptive autonomic regulation in PTSD accelerates physiological aging
Williamson, J. B., Porges, E. C., Lamb, D. G., & Porges, S. W. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.01571 · Cited by 116 · see citing works
“Loneliness predicts reduced physical activity (Hawkley et al., 2009) and increased blood pressure in older adults (Hawkley et al., 2009, 2006).”
BackgroundResultMarin, M.-F., Camprodon, J. A., Dougherty, D. D., & Milad, M. R. (2014) · Depression and Anxiety · doi:10.1002/da.22252 · Cited by 106 · see citing works
- Authors
- Fanselow, M. S.
- Affiliations
- University of California, Los Angeles (US)
- Corresponding author
- Fanselow, Michael S.
- ORCID
- Fanselow, Michael S.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2013-06
- Volume
- 73
- Issue
- 11
- Pages
- 1043-1044
- ISSN
- 0006-3223 (ISSN-L)
- PMC
- PMC4176918
- OpenAlex
- W2128961201
- Cited by
- 30
- References
- 3
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 2 · 2022: 6 · 2021: 1 · 2019: 4 · 2018: 1 · 2017: 6 · 2016: 1 · 2015: 2 · 2014: 2
- FWCI
- 0.94
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01-MH62122, R01MH062122)
- Topics
- Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Keywords
- vagus nerve stimulation, anxiety disorders, fear, Pavlovian extinction, exposure therapy, cognitive behavioral therapy, adjunctive therapy, translational research
- MeSH terms
- Animals, Conditioning, Classical, Extinction, Psychological, Fear, Male, Vagus Nerve Stimulation
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