The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
DHEA and DHEA-S response to acute psychosocial stress in healthy men and women
Abstract
This study investigates the effect of acute psychosocial stress on serum concentrations of DHEA and DHEA-S in healthy men and women. Twenty men and 19 women (age 30-50 years) underwent Trier Social Stress Test (TSST). Physiological measurements were performed before, directly after the stress test and after 30 mins of recovery. In both men and women, significantly elevated DHEA and DHEA-S levels were observed in response to the stressor. There was a large inter-individual variation in the magnitude of the response, especially for DHEA but no statistical difference between men and women. Magnitude of the change in the levels of DHEA was found to be positively associated with the magnitude of the changes in ACTH, cortisol and heart rate. Furthermore, the results of this study suggest that the capacity to secrete DHEA and DHEA-S during acute psychosocial stress declines with age.
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“DHEA is secreted synchronously with cortisol in response to ACTH, and has been shown to be elevated in response to psychosocial stress (Izawa et al., 2008; Lennartsson et al., 2012; Morgan et al., 2004).”
From Effect of oxytocin on craving and stress response in marijuana-dependent individuals: A pilot study (2013) · cites this paper as Lennartsson et al., 2012
In the citing paper
“data from a previous study demonstrates that there is significant individual variability in the DHEA response to social stress (Lennartsson et al., 2012).”
From Effects of adverse childhood experiences on the association between intranasal oxytocin and social stress reactivity among individuals with cocaine dependence (2015) · cites this paper as Lennartsson et al., 2012
Citations
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Shields, G. S., Sazma, M. A., & Yonelinas, A. P. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.06.038 · Cited by 818
Biological and psychological markers of stress in humans: Focus on the Trier Social Stress Test
Allen, A. P., Kennedy, P. J., Cryan, J. F., Dinan, T. G., & Clarke, G. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.11.005 · Cited by 734
The Trier Social Stress Test: Principles and practice
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Cortisol and DHEA in development and psychopathology
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Metadata
- Authors
- Lennartsson, A.-K., Kushnir, M. M., Bergquist, J., & Jonsdottir, I. H.
- Affiliations
- University of Gothenburg (SE)
- Uppsala University (SE)
- Corresponding author
- Lennartsson, Anna-Karin
- Venue
- Biological Psychology
- Publisher
- Elsevier BV
- Published
- 2012-05
- Volume
- 90
- Issue
- 2
- Pages
- 143-149
- ISSN
- 0301-0511 (ISSN-L)
- OpenAlex
- W2081280682
- Cited by
- 173
- References
- 39
- Citations by year
- 2026: 6 · 2025: 16 · 2024: 5 · 2023: 11 · 2022: 12 · 2021: 16 · 2020: 20 · 2019: 15 · 2018: 8 · 2017: 9 · 2016: 19 · 2015: 11 · 2014: 13 · 2013: 8 · 2012: 4
- FWCI
- 4.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Keywords
- dehydroepiandrosterone, dehydroepiandrosterone sulfate, acute psychosocial stress, Trier Social Stress Test, sex differences, interindividual variability, ACTH, cortisol, heart rate, aging, stress response
- MeSH terms
- Adrenocorticotropic Hormone, Adult, Blood Pressure, Dehydroepiandrosterone, Female, Heart Rate, Humans, Hydrocortisone, Male, Psychiatric Status Rating Scales, Radioimmunoassay, Sex Characteristics, Stress, Psychological, Dehydroepiandrosterone Sulfate
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