The DOI matches its Crossref record; 32 of the 34 references it cites were found in a registry or an index.
Feeding strategies for enhanced lactobionic acid production from whey by Pseudomonas taetrolens
Open accessAbstract
High-level production of lactobionic acid from whey by Pseudomonas taetrolens under fed-batch fermentation was achieved in this study. Different feeding strategies were evaluated according to the physiological status and fermentation performance of P. taetrolens. A lactobionic acid titer of 164 g/L was obtained under co-feeding conditions affording specific and volumetric productivities of 1.4 g/g h and 2.05 g/L h, respectively. Flow cytometry assessment revealed that P. taetrolens cells exhibited a robust physiological status, which makes them particularly well-suited for employing concentrated nutrient solutions to further prolong the growth and production phases. Such detailed knowledge of the physiological status has been revealed to be a key issue to further support the development of high-yield lactobionic acid production processes under feeding strategies. The present study has demonstrated the feasibility of P. taetrolens to achieve high-level bio-production of lactobionic acid from whey through fed-batch cultivation, suggesting its major potential for industrial-scale implementation.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It has been demonstrated that Pseudomonas taetrolens was able to produce high-purity lactobionic acid when cultivated in the fed-batch culture under co-feeding conditions using highly concentrated whey with yeast extract and peptone [100].”
From Use of Waste from the Food Industry and Applications of the Fermentation Process to Create Sustainable Cosmetic Products: A Review (2024) · cites this paper as [100]
Citations
Cites
Southard, J. H., & Belzer, F. O. (1995) · Annual Review of Medicine · doi:10.1146/annurev.med.46.1.235 · Cited by 403
Application of flow cytometry to industrial microbial bioprocesses
Díaz, M., Herrero, M., García, L. A., & Quirós, C. (2009) · Biochemical Engineering Journal · doi:10.1016/j.bej.2009.07.013 · Cited by 307
Self-citationPolyhydroxyalkanoate production from whey by Pseudomonas hydrogenovora
Koller, M., Bona, R., Chiellini, E., Fernandes, E. G., Horvat, P., Kutschera, C., Hesse, P. J., & Braunegg, G. (2007) · Bioresource Technology · doi:10.1016/j.biortech.2007.09.049 · Cited by 222
Ahn, W. S., Park, S. J., & Lee, S. Y. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.8.3624-3627.2000 · Cited by 195
Clinical and cosmeceutical uses of hydroxyacids
Green, B. A., Yu, R. J., & Scott, E. J. V. (2009) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2009.06.023 · Cited by 177
Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment
Park, I., Yang, J., Jeong, H., Bom, H., Harada, I., Akaike, T., Kim, S., & Cho, C. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00108-x · Cited by 162
Nath, A., Dixit, M., Bandiya, A., Chavda, S., & Desai, A. J. (2007) · Bioresource Technology · doi:10.1016/j.biortech.2007.10.017 · Cited by 154
Selim, K. M. K., Ha, Y.-S., Kim, S.-J., Chang, Y., Kim, T., Lee, G. H., & Kang, I. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.09.014 · Cited by 154
Origin and analysis of microbial population heterogeneity in bioprocesses
Müller, S., Harms, H., & Bley, T. (2010) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2010.01.002 · Cited by 141
Hewitt, C. J., & Nebe‐von‐Caron, G. (2004) · Advances in biochemical engineering, biotechnology · doi:10.1007/b93997 · Cited by 141
Tang, Y., Zhang, W. Y., & Zhong, J. (2008) · Bioresource Technology · doi:10.1016/j.biortech.2008.10.005 · Cited by 117
Hewitt, C. J., Caron, G. N., Nienow, A. W., & McFarlane, C. M. (1999) · Journal of Biotechnology · doi:10.1016/s0168-1656(99)00168-6 · Cited by 94
Kuusisto, J., Tokarev, A. V., Murzina, E. V., Roslund, M. U., Mikkola, J., Murzin, D. Y., & Salmi, T. (2007) · Catalysis Today · doi:10.1016/j.cattod.2006.11.020 · Cited by 84
Efficient lactobionic acid production from whey by Pseudomonas taetrolens under pH-shift conditions
Alonso, S., Rendueles, M., & Dı́az, M. (2011) · Bioresource Technology · doi:10.1016/j.biortech.2011.07.089 · Cited by 72
Self-citationYu, Z., Du, G., Zhou, J., & Chen, J. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.03.021 · Cited by 68
Fermentative Production of Lactobionic Acid by Burkholderia cepacia
Murakami, H., Seko, A., Azumi, M., Ueshima, N., Yoshizumi, H., Nakano, H., & Kitahata, S. (2003) · Journal of Applied Glycoscience · doi:10.5458/jag.50.117 · Cited by 48
Malvessi, E., Carra, S., Pasquali, F. C., Kern, D. B., da Silveira, M. M., & Ayub, M. A. Z. (2012) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-012-1198-6 · Cited by 46
Peng, J., Wang, K., Tan, W.-H., He, X., He, C., Wu, P., & Liu, F. (2006) · Talanta · doi:10.1016/j.talanta.2006.05.064 · Cited by 46
A periplasmic, pyridoxal-5′-phosphate-dependent amino acid racemase in Pseudomonas taetrolens
Matsui, D., Oikawa, T., Arakawa, N., Osumi, S., Lausberg, F., Stäbler, N., Freudl, R., & Eggeling, L. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-009-1942-7 · Cited by 44
Alonso, S., Rendueles, M., & Dı́az, M. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.01.045 · Cited by 41
Self-citationProduction of lactobionic acid from whey by Pseudomonas sp. LS13-1
Miyamoto, Y., Ooi, T., & Kinoshita, S. (2000) · Biotechnology Letters · doi:10.1023/a:1005617903152 · Cited by 39
Want, A., Thomas, O. R. T., Kara, B., Liddell, J. M., & Hewitt, C. J. (2008) · Cytometry Part A · doi:10.1002/cyto.a.20683 · Cited by 38
Pedruzzi, I., da Silva, E. A. B., & Rodrigues, A. E. (2011) · Enzyme and Microbial Technology · doi:10.1016/j.enzmictec.2011.04.017 · Cited by 38
Microbial Conversion of Lactose to Lactobionic Acid by Resting Cells of Burkholderia cepacia No. 24
洋, 村., Seko, A., Azumi, M., Kiso, T., Kiryu, T., Kitahata, S., 裕司, 島., & Nakano, H. (2006) · Journal of Applied Glycoscience · doi:10.5458/jag.53.7 · Cited by 35
Physiological heterogeneity of Pseudomonas taetrolens during lactobionic acid production
Alonso, S., Rendueles, M., & Dı́az, M. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-4254-2 · Cited by 32
Self-citationPedruzzi, I., Malvessi, E., Mata, V. G., Silva, E. A. B., da Silveira, M. M., & Rodrigues, A. E. (2007) · Journal of Chromatography A · doi:10.1016/j.chroma.2007.01.051 · Cited by 29
Alonso, S., Rendueles, M., & Dı́az, M. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-4607-x · Cited by 24
Self-citationda Silva, T. L., Feijão, D., Roseiro, J. C., & dos Reis, A. J. D. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.10.008 · Cited by 23
Catalytic Wet Oxidation of Lactose
Chia, Y. N., Latusek, M. P., & Holles, J. H. (2008) · Industrial & Engineering Chemistry Research · doi:10.1021/ie701779u · Cited by 21
Large-scale production of lactobionic acid - use and new applications
Gerling, K. G. (1998) · Cited by 17
Fed-batch bioconversion of indene to cis-indandiol
Amanullah, A., Hewitt, C. J., Nienow, A. W., Lee, C., Chartrain, M. M., Buckland, B. C., Drew, S. W., & Woodley, J. M. (2002) · Enzyme and Microbial Technology · doi:10.1016/s0141-0229(02)00183-7 · Cited by 15
da Silva, T. L., Piekova, L., Mileu, J., & Roseiro, J. C. (2009) · Enzyme and Microbial Technology · doi:10.1016/j.enzmictec.2009.03.001 · Cited by 13
Cited by
The biotechnological potential of whey
Ryan, M. P., & Walsh, G. (2016) · Reviews in Environmental Science and Bio/Technology · doi:10.1007/s11157-016-9402-1 · Cited by 212
Bio-production of lactobionic acid: Current status, applications and future prospects
Alonso, S., Rendueles, M., & Dı́az, M. (2013) · Biotechnology Advances · doi:10.1016/j.biotechadv.2013.04.010 · Cited by 144
Self-citationMicrobial production of specialty organic acids from renewable and waste materials
Alonso, S., Rendueles, M., & Dı́az, M. (2014) · Critical Reviews in Biotechnology · doi:10.3109/07388551.2014.904269 · Cited by 127
Self-citationWhey-derived valuable products obtained by microbial fermentation
Pescuma, M., de Valdez, G. F., & Mozzi, F. (2015) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-015-6766-z · Cited by 125
Cultivation modes for microbial oil production using oleaginous yeasts – A review
Karamerou, E. E., & Webb, C. (2019) · Biochemical Engineering Journal · doi:10.1016/j.bej.2019.107322 · Cited by 96
Metadata
- Authors
- Alonso, S., Rendueles, M., & Díaz, M.
- Affiliations
- Universidad de Oviedo (ES)
- Venue
- Bioresource Technology
- Publisher
- Elsevier BV
- Published
- 2013-04
- Volume
- 134
- Pages
- 134-142
- ISSN
- 0960-8524 (ISSN-L)
- OpenAlex
- W2051962386
- Cited by
- 48
- References
- 34
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 3 · 2022: 9 · 2021: 4 · 2020: 5 · 2019: 3 · 2018: 5 · 2017: 4 · 2016: 3 · 2015: 4 · 2014: 1 · 2013: 3
- FWCI
- 1.64
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Bioresource Technology (publishedVersion)
- PubMed (publishedVersion)
- Consultation of the Doctoral Thesis Database (TESEO) (Ministerio de Educación, Cultura y Deporte) (submittedVersion, cc-by-nc-nd)
- Funders
- Ministerio de Economía y Competitividad
- Ministerio de Ciencia e Innovación
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
- Keywords
- lactobionic acid, whey, Pseudomonas taetrolens, fed-batch fermentation, feeding strategies, co-feeding, fermentation physiology, flow cytometry, biotransformation, industrial fermentation
- MeSH terms
- Biotechnology, Dairy Products, Disaccharides, Hydrogen-Ion Concentration, Pseudomonas, Time Factors, Biomass, Bioreactors, Batch Cell Culture Techniques
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
