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Laccase-assisted degradation of emerging recalcitrant compounds – A review
Abstract
The main objective of this review is to provide up to date, brief, irrefutable, organized data on the conducted experiments on a range of emerging recalcitrant compounds such as Diclofenac (DCF), Chlorophenols (CPs), tetracycline (TCs), Triclosan (TCS), Bisphenol A (BPA) and Carbamazepine (CBZ). These compounds were selected from the categories of pharmaceutical contaminants (PCs), endocrine disruptors (EDs) and personal care products (PCPs) on the basis of their toxicity and concentration retained in the environment. In this context, detailed mechanism of laccase mediated degradation has been conversed that laccase assisted degradation occurs by one electron oxidation involving redox potential as underlying element of the process. Further, converging towards biotechnology, laccase immobilization increased removal efficiency, storage and reusability through various experimentally conducted studies. Laccase is being considered noteworthy as mediators facilitate laccase in oxidation of non-phenolic compounds and thereby increasing its substrate range which is being discussed in further in the review. The laccase assisted degradation mechanism of each compound has been elucidated but further studies to undercover proper degradation mechanisms needs to be performed.
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“Within their active sites, these enzymes harbor four copper atoms, categorized into three types: single “blue” copper (type 1, T1), single “non-blue” copper (type 2, T2), and a copper-copper pair (type 3, T3) (143, 144).”
From Toward the development of a molecular toolkit for the microbial remediation of per-and polyfluoroalkyl substances (2024) · cites this paper as [144]
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“This renders them extensively applicable in the oxidative removal of various pollutants, such as herbicides, synthetic dyes, and pharmaceuticals (134, 143, 144).”
From Toward the development of a molecular toolkit for the microbial remediation of per-and polyfluoroalkyl substances (2024) · cites this paper as [144]
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“Examples of such mediators include 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and 1-hydroxybenzotriazole (HBT) (144, 145).”
From Toward the development of a molecular toolkit for the microbial remediation of per-and polyfluoroalkyl substances (2024) · cites this paper as [144]
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Removal of pharmaceutical compounds in water and wastewater using fungal oxidoreductase enzymes
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Ashe, B., Nguyen, L. N., Hai, F. I., Lee, D.-J., van de Merwe, J. P., Leusch, F. D. L., Price, W. E., & Nghiem, L. D. (2016) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2016.04.027 · Cited by 133
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Cited by
Sorted by citations
Hu, M., & Scott, C. (2024) · Applied and Environmental Microbiology · doi:10.1128/aem.00157-24 · Cited by 63
Metadata
- Authors
- Bhardwaj, P., Kaur, N., Selvaraj, M., Ghramh, H. A., Al-Shehri, B. M., Singh, G., Arya, S. K., Bhatt, K., Ghotekar, S., Mani, R., Chang, S. W., Ravindran, B., & Awasthi, M. K.
- Venue
- Bioresource Technology
- Publisher
- Elsevier BV
- Published
- 2022-11
- Volume
- 364
- Pages
- 128031
- ISSN
- 0960-8524
- Cited by
- 101
- References
- 2
- Language
- en
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- CoChat. (2026). Citation check: Laccase-assisted degradation of emerging recalcitrant compounds – A review. https://app.cochat.ai/papers/10.1016/j.biortech.2022.128031
- The paper
- Bhardwaj, P., Kaur, N., Selvaraj, M., Ghramh, H. A., Al-Shehri, B. M., Singh, G., Arya, S. K., Bhatt, K., Ghotekar, S., Mani, R., Chang, S. W., Ravindran, B., & Awasthi, M. K. (2022). Laccase-assisted degradation of emerging recalcitrant compounds – A review. Bioresource Technology. https://doi.org/10.1016/j.biortech.2022.128031