The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Advances in microfluidic PCR for point-of-care infectious disease diagnostics
Open accessAbstract
Global burdens from existing or emerging infectious diseases emphasize the need for point-of-care (POC) diagnostics to enhance timely recognition and intervention. Molecular approaches based on PCR methods have made significant inroads by improving detection time and accuracy but are still largely hampered by resource-intensive processing in centralized laboratories, thereby precluding their routine bedside- or field-use. Microfluidic technologies have enabled miniaturization of PCR processes onto a chip device with potential benefits including speed, cost, portability, throughput, and automation. In this review, we provide an overview of recent advances in microfluidic PCR technologies and discuss practical issues and perspectives related to implementing them into infectious disease diagnostics.
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Citations
Cites
The origins and the future of microfluidics
Whitesides, G. M. (2006) · Nature · doi:10.1038/nature05058 · Cited by 9,687
Bacterial Persistence as a Phenotypic Switch
Balaban, N. Q., Merrin, J., Chait, R., Kowalik, L., & Leibler, S. (2004) · Science · doi:10.1126/science.1099390 · Cited by 2,952 · cited 1×
“Microfluidics is an attractive approach for susceptibility testing by providing a miniaturized fluidic environment suitable for monitoring cell growth in the presence of antibiotics (Balaban et al. , 2004, Orit and Nathalie, 2009).”
BackgroundVogelstein, B., & Kinzler, K. W. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.9236 · Cited by 1,770
Multiplex PCR: Optimization and Application in Diagnostic Virology
Elnifro, E. M., Ashshi, A. M., Cooper, R. J., & Klapper, P. E. (2000) · Clinical Microbiology Reviews · doi:10.1128/cmr.13.4.559-570.2000 · Cited by 964
Microdroplet-based PCR enrichment for large-scale targeted sequencing
Tewhey, R., Warner, J. B., Nakano, M., Libby, B., Medkova, M., David, P. H., Kotsopoulos, S. K., Samuels, M. L., Hutchison, J. B., Larson, J. W., et al. (2009) · Nature Biotechnology · doi:10.1038/nbt.1583 · Cited by 454 · cited 1×
“…amplification and quantification in millions of droplets have been demonstrated for large scale genomic sequencing (Kiss et al. , 2008, Mazutis et al. , 2009a, Tewhey et al. , 2009) and digital detection of pathogenic E. coli O157 cells in a high background of normal K12 cells (Zeng et al. , 2010).”
Cited by
Antibiotic resistance-the need for global solutions
Laxminarayan, R., Duse, A., Wattal, C., Zaidi, A. K. M., Wertheim, H. F. L., Sumpradit, N., Vlieghe, E., Hara, G. L., Gould, I. M., Goossens, H., et al. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70318-9 · Cited by 4,439
Point-of-care diagnostics for infectious diseases: From methods to devices
Wang, C., Liu, M., Wang, Z., Li, S., Deng, Y., & He, N. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101092 · Cited by 622
Current and Emerging Methods of Antibiotic Susceptibility Testing
Khan, Z. A., Siddiqui, M. F., & Park, S. (2019) · Diagnostics · doi:10.3390/diagnostics9020049 · Cited by 442
Self-citationPoint-of-care microfluidic devices for pathogen detection
Nasseri, B., Soleimani, N., Rabiee, N., Kalbasi, A., Karimi, M., & Hamblin, M. R. (2018) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2018.05.050 · Cited by 382
Sweeney, T. E., Shidham, A., Wong, H. R., & Khatri, P. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa5993 · Cited by 332
Metadata
- Authors
- Park, S., Zhang, Y., Lin, S., Wang, T.-H., & Yang, S.
- Venue
- Biotechnology Advances
- Publisher
- Elsevier BV
- Published
- 2011-11
- Volume
- 29
- Issue
- 6
- Pages
- 830-839
- ISSN
- 0734-9750 (ISSN-L)
- OpenAlex
- W2053185702
- Cited by
- 299
- References
- 5
- FWCI
- 13.13
- Type
- journal article
- Language
- en
- Open access
- green
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- Park, S., Zhang, Y., Lin, S., Wang, T.-H., & Yang, S. (2011). Advances in microfluidic PCR for point-of-care infectious disease diagnostics. Biotechnology Advances. https://doi.org/10.1016/j.biotechadv.2011.06.017
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
