The DOI matches its Crossref record; 168 of the 168 references it cites were found in a registry or an index.
Advances in nanoparticle and microparticle delivery systems for increasing the dispersibility, stability, and bioactivity of phytochemicals
Open accessAbstract
Application of bioactive phytochemicals in foods, supplements, and pharmaceuticals is often limited because of their poor solubility, stability, and bioavailability. Phytochemical oral delivery systems (PODS), consisting of phytochemical-loaded nanoparticles or microparticles, can overcome these challenges. PODS can be produced in liquid, gel, paste, or solid forms. They must be carefully formulated to be compatible with the product matrix, economical, robust, and maintain phytochemical bioactivity. This review evaluates recent advances in the development of PODS, including microemulsions, nanoemulsions, emulsions, solid lipid nanoparticles, liposomes, and biopolymer microgels. Properly designed PODS will increase phytochemical applications in commercial products.
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Cites
Intermolecular and Surface Forces
(2011) · Intermolecular and Surface Forces · doi:10.1016/b978-0-12-391927-4.10024-6 · Cited by 16,923
Solid lipid nanoparticles (SLN) for controlled drug delivery â a review of the state of the art
Müller, R. (2000) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(00)00087-4 · Cited by 3,759
Food Emulsions: Principles, Practice, and Techniques
McClements, D. J. (1998) · ScholarWorks@UMassAmherst (University of Massachusetts Amherst) · Cited by 2,476
Self-citationLipids and Lipid-Based Formulations: Optimizing the Oral Delivery of Lipophilic Drugs
Porter, C. J. H., Trevaskis, N. L., & Charman, W. N. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2197 · Cited by 1,824
Nanoemulsions versus microemulsions: terminology, differences, and similarities
McClements, D. J. (2012) · Soft Matter · doi:10.1039/c2sm06903b · Cited by 1,778
Self-citationMcClements, D. J., & Rao, J. (2011) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2011.559558 · Cited by 1,630
Self-citationOral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers
Ensign, L. M., Cone, R., & Hanes, J. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.12.009 · Cited by 1,623
Strategies to Address Low Drug Solubility in Discovery and Development
Williams, H. D., Trevaskis, N. L., Charman, S. A., Shanker, R. M., Charman, W. N., Pouton, C. W., & Porter, C. J. H. (2013) · Pharmacological Reviews · doi:10.1124/pr.112.005660 · Cited by 1,570
Solid lipid nanoparticles for parenteral drug delivery
Wissing, S. A., Kayser, O., & Müller, R. H. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.12.002 · Cited by 1,495
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Cited by
Traditional and innovative approaches for the extraction of bioactive compounds
Usman, I., Hussain, M., Imran, A., Afzaal, M., Saeed, F., Javed, M., Afzal, A., Ashfaq, I., Al Jbawi, E., & A. Saewan, S. (2022) · International Journal of Food Properties · doi:10.1080/10942912.2022.2074030 · Cited by 209
“Mc-Clements et al.([24]) illustrated bioavailability (BA) of phytochemicals depend upon four basic factors:”
BackgroundMachado, A. R., Silva, P. M. P., Vicente, A. A., Souza-Soares, L. A., Pinheiro, A. C., & Cerqueira, M. A. (2022) · Polymers · doi:10.3390/polym14214759 · Cited by 57
Metadata
- Authors
- McClements, D. J.
- Venue
- Biotechnology Advances
- Publisher
- Elsevier BV
- Published
- 2020-01
- Volume
- 38
- Pages
- 107287
- ISSN
- 0734-9750 (ISSN-L)
- OpenAlex
- W2886056161
- Cited by
- 322
- References
- 168
- FWCI
- 19.84
- Type
- journal article
- Language
- en
- Open access
- bronze
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- McClements, D. J. (2020). Advances in nanoparticle and microparticle delivery systems for increasing the dispersibility, stability, and bioactivity of phytochemicals. Biotechnology Advances. https://doi.org/10.1016/j.biotechadv.2018.08.004
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
