The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K
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Citations
Cites
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
Saftig, P., Hunziker, E., Wehmeyer, O., Jones, S., Boyde, A., Rommerskirch, W., Moritz, J. D., Schu, P., & von Figura, K. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.23.13453 · Cited by 913
Cathepsin L: Critical Role in Ii Degradation and CD4 T Cell Selection in the Thymus
Nakagawa, T., Roth, W., Wong, P., Nelson, A., Farr, A., Deussing, J., Villadangos, J. A., Ploegh, H., Peters, C., & Rudensky, A. Y. (1998) · Science · doi:10.1126/science.280.5362.450 · Cited by 674
Phagocytosis and intracellular digestion of collagen, its role in turnover and remodelling
Everts, V., van der Zee, E., Creemers, L., & Beertsen, W. (1996) · The Histochemical Journal · doi:10.1007/bf02409011 · Cited by 342
Falgueyret, J., Desmarais, S., Oballa, R. M., et al. (2005) · Journal of Medicinal Chemistry · doi:10.1021/jm0504961 · Cited by 152
Self-citationTrifluoroethylamines as amide isosteres in inhibitors of cathepsin K
Black, W. C., Bayly, C. I., Davis, D. E., Desmarais, S., Falgueyret, J., Léger, S., Li, C. S., Massé, F., McKay, D. J., Palmer, J. T., et al. (2005) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2005.07.071 · Cited by 142
Self-citationNakagawa, S., Pawelek, P., & Grinnell, F. (1989) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12284425 · Cited by 137
Kumar, S., Dare, L. C., Vasko-Moser, J. A., et al. (2006) · Bone · doi:10.1016/j.bone.2006.07.015 · Cited by 137
Fracture Incidence and Characterization in Patients on Osteoporosis Treatment: The ICARO Study
Adami, S., Isaia, G., Luisetto, G., Minisola, S., SINIGAGLIA, L., Gentilella, R., Agnusdei, D., Iori, N., & Nuti, R. (2006) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.060715 · Cited by 125
A Critical Role for the Membrane-type 1 Matrix Metalloproteinase in Collagen Phagocytosis
Lee, H., Overall, C. M., McCulloch, C. A., & Sodek, J. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-06-0486 · Cited by 114
Difluoroethylamines as an amide isostere in inhibitors of cathepsin K
Isabel, É., Mellon, C., Boyd, M. J., Chauret, N., Deschênes, D., Desmarais, S., Falgueyret, J., Gauthier, J. Y., Khougaz, K., Lau, C. K., et al. (2010) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2010.12.070 · Cited by 111
Self-citation
Cited by
Osteoporosis: now and the future
Rachner, T. D., Khosla, S., & Hofbauer, L. C. (2011) · The Lancet · doi:10.1016/s0140-6736(10)62349-5 · Cited by 2,696
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
Meanwell, N. A. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b01788 · Cited by 2,655
Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore
Fleming, F. F., Yao, L., Ravikumar, P. C., Funk, L., & Shook, B. C. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm100762r · Cited by 1,754
Extracellular Matrix Molecules: Potential Targets in Pharmacotherapy
Järveläinen, H., Sainio, A., Koulu, M., Wight, T. N., & Penttinen, R. (2009) · Pharmacological Reviews · doi:10.1124/pr.109.001289 · Cited by 566
Chemical Aspects of Human and Environmental Overload with Fluorine
Han, J., Kiss, L., Mei, H., Remete, A. M., Ponikvar-Svet, M., Sedgwick, D. M., Roman, R., Fustero, S., Moriwaki, H., & Soloshonok, V. A. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01263 · Cited by 537
Metadata
- Authors
- Gauthier, J. Y., Chauret, N., Cromlish, W., Desmarais, S., Duong, L. T., Falgueyret, J.-P., Kimmel, D. B., Lamontagne, S., Léger, S., LeRiche, T., Li, C. S., Massé, F., McKay, D. J., Nicoll-Griffith, D. A., Oballa, R. M., Palmer, J. T., Percival, M. D., Riendeau, D., Robichaud, J., Rodan, G. A., Rodan, S. B., Seto, C., Thérien, M., Truong, V.-L., Venuti, M. C., Wesolowski, G., Young, R. N., Zamboni, R., & Black, W. C.
- Venue
- Bioorganic & Medicinal Chemistry Letters
- Publisher
- Elsevier BV
- Published
- 2008-02
- Volume
- 18
- Issue
- 3
- Pages
- 923-928
- ISSN
- 0960-894X (ISSN-L)
- OpenAlex
- W2010654750
- Cited by
- 477
- References
- 17
- FWCI
- 8.49
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K. https://app.cochat.ai/papers/10.1016/j.bmcl.2007.12.047
- The paper
- Gauthier, J. Y., Chauret, N., Cromlish, W., Desmarais, S., Duong, L. T., Falgueyret, J.-P., Kimmel, D. B., Lamontagne, S., Léger, S., LeRiche, T., Li, C. S., Massé, F., McKay, D. J., Nicoll-Griffith, D. A., Oballa, R. M., Palmer, J. T., Percival, M. D., Riendeau, D., Robichaud, J., . . . Black, W. C. (2008). The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K. Bioorganic & Medicinal Chemistry Letters. https://doi.org/10.1016/j.bmcl.2007.12.047
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
