The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.
Provoking symptoms to relieve symptoms: A randomized controlled dismantling study of exposure therapy in irritable bowel syndrome
Abstract
An internet-delivered cognitive behavioral treatment (ICBT) based on systematic exposure exercises has previously shown beneficial effects for patients with irritable bowel syndrome (IBS). Exposure exercises may be perceived as difficult for patients to perform because of the elicited short-term distress and clinicians may be reluctant to use these interventions. The aim of this study was to compare ICBT with the same protocol without systematic exposure (ICBT-WE) to assess if exposure had any incremental value. This randomized controlled dismantling study included 309 participants diagnosed with IBS. The treatment interventions lasted for 10 weeks and included online therapist contact. ICBT-WE comprised mindfulness, work with life values, acceptance, and encouraged reduced avoidance behaviors, while ICBT also included systematic exposure to IBS symptoms and related situations. Severity of IBS symptoms was measured with the Gastrointestinal Symptom Rating Scale - IBS version (GSRS-IBS). The between-group Cohen's d on GSRS-IBS was 0.47 (95% CI: 0.23-0.70) at post-treatment and 0.48 (95% CI: 0.20-0.76) at 6-month follow-up, favoring ICBT. We conclude that the systematic exposure included in the ICBT protocol has incremental effects over the other components in the protocol. This study provides evidence for the utility of exposure exercises in psychological treatments for IBS.
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In the citing paper
“Studies focusing on internet-delivered therapy for patients with medical speciality FSSs such as irritable bowel syndrome [[24], [25], [26]], fibromyalgia [27], chronic pain [28,29] and non-cardiac chest pain [30], as well as somatic symptom distress [31] have shown promising results for internet-delivered treatments compared with waiting list or active control conditions.”
From Internet-delivered treatment for patients suffering from severe functional somatic disorders: Protocol for a randomized controlled trial (2023) · cites this paper as [24]
In the citing paper
“IBS-QOL: (ES: 0.31)”
From Third wave treatments for functional somatic syndromes and health anxiety across the age span: A narrative review (2019) · cites this paper as Ljótsson et al. (2014)
In the citing paper
“Especially noteworthy here are the studies on acceptance-based exposure-based therapy for IBS (Ljótsson et al., 2010; Ljótsson et al., 2011), where acceptance-based techniques, mindfulness training and strict exposure training are combined to produce consistently large effects, and where the exposure element has been shown to add considerable effect (Ljótsson et al., 2014).”
From Third wave treatments for functional somatic syndromes and health anxiety across the age span: A narrative review (2019) · cites this paper as Ljótsson et al., 2014
In the citing paper
“IBS symptom severity (GSRS-IBS): + (ES: 0.44)”
From Third wave treatments for functional somatic syndromes and health anxiety across the age span: A narrative review (2019) · cites this paper as Ljótsson et al. (2014)
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Internet-Delivered Psychological Treatments
Andersson, G. (2016) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-021815-093006 · Cited by 595
A Rome Working Team Report on Brain-Gut Behavior Therapies for Disorders of Gut-Brain Interaction
Keefer, L., Ballou, S. K., Drossman, D. A., Ringstrom, G., Elsenbruch, S., & Ljótsson, B. (2022) · Gastroenterology · doi:10.1053/j.gastro.2021.09.015 · Cited by 213
“…as part of gut-brain dysregulation can often be quite helpful in convincing patients to pursue BGBT, particularly exposure-based CBT. 59,60 Laboratory studies have underscored that prior experience and learning processes, comprising classical conditioning, instrumental learning, and…”
BackgroundSelf-citationEveritt, H. A., Landau, S., O’Reilly, G., Sibelli, A., Hughes, S., Windgassen, S., Holland, R., Little, P., McCrone, P., Bishop, F., et al. (2019) · Gut · doi:10.1136/gutjnl-2018-317805 · Cited by 198
Labanski, A., Langhorst, J., Engler, H., & Elsenbruch, S. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.104501 · Cited by 200
Hesser, H. (2015) · Internet Interventions · doi:10.1016/j.invent.2015.02.003 · Cited by 192
“There are also several examples of studies in the literature of internet interventions that use maximum likelihood estimation to cope efficiently with data loss under MAR (e.g., Hesser et al., 2012; Ljótsson et al., 2014; Newby et al., 2013).”
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Metadata
- Authors
- Ljótsson, B., Hesser, H., Andersson, E., Lackner, J. M., El Alaoui, S., Falk, L., Aspvall, K., Fransson, J., Hammarlund, K., Löfström, A., Nowinski, S., Lindfors, P., & Hedman, E.
- Affiliations
- Karolinska Institutet (SE)
- Linköping University (SE)
- Karolinska University Hospital (SE)
- Erie County Medical Center (US)
- Sabbatsberg Hospital (SE)
- Corresponding author
- Ljótsson, Brjánn
- ORCID
- Venue
- Behaviour Research and Therapy
- Publisher
- Elsevier BV
- Published
- 2014-04
- Volume
- 55
- Pages
- 27-39
- ISSN
- 0005-7967 (ISSN-L)
- OpenAlex
- W2034003089
- Cited by
- 141
- References
- 71
- Citations by year
- 2026: 7 · 2025: 13 · 2024: 12 · 2023: 11 · 2022: 15 · 2021: 14 · 2020: 12 · 2019: 11 · 2018: 11 · 2017: 15 · 2016: 7 · 2015: 9 · 2014: 4
- FWCI
- 11.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behaviour Research and Therapy (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- irritable bowel syndrome, exposure therapy, symptom provocation, mindfulness, acceptance and commitment therapy, avoidance behavior, gastrointestinal symptom severity
- MeSH terms
- Adult, Combined Modality Therapy, Female, Humans, Implosive Therapy, Male, Therapy, Computer-Assisted, Cognitive Behavioral Therapy, Treatment Outcome, Internet, Irritable Bowel Syndrome, Young Adult
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