Cited by 112Nanoplatforms for cancer theranosticsUltrasound and Hyperthermia ApplicationsPhotoacoustic and Ultrasonic Imaging

Ultrasound nanotheranostics in fighting cancer: Advances and prospects

Zhou, Li-Qiang, Li, Pan, Cui, Xin-Wu, Dietrich, Christoph F.·2020·Cancer Letters

Abstract

The intrinsic limits of conventional ultrasound microbubble contrast agent greatly promoted the development and application of various nanomaterials for more efficient cancer ultrasound theranostics. Considerable successes have been achieved in the field of ultrasound molecular imaging and targeted therapy for tumor based on nanoparticulate theranostic agents. This review summarizes and discusses the emerging development on exploring organic and inorganic nanomaterials for ultrasound-based tumor diagnositic applications, and as synergistic agents for ultrasound targeted therapy in fighting cancer. The relationship between structure/composition and functionality of nanomaterials for ultrasound theranostic is discussed and revealed in detail. Finally, the further development and challenges facing clinical implementation of ultrasound nanomedicine are discussed. As a highly promising and valuable tumor-specific theranostic methodology, it is believed that ultrasound nanomedicine would pave a novel but efficient way for combating cancer.

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Registry

Crossref · 10.1016/j.canlet.2019.11.034

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92 of 92 references verified0 citation errors · 0 not checkable

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  • Ultrasound has become a common external trigger approach for cancer treatment.

    “As a result, it has become a common external trigger approach for cancer treatment.177,178”

    From Smart nanoparticles for cancer therapy (2023) · cites this paper as [177]

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Authors
Zhou, L.-Q., Li, P., Cui, X.-W., & Dietrich, C. F.
Affiliations
  • Second Affiliated Hospital of Chongqing Medical University (CN)
  • Tongji Hospital (CN)
Corresponding author
Cui, Xin-Wu
Venue
Cancer Letters
Publisher
Elsevier BV
Published
2020-02
Volume
470
Pages
204-219
ISSN
0304-3835 (ISSN-L)
OpenAlex
W2991352583
Cited by
112
References
92
Citations by year
2026: 7 · 2025: 18 · 2024: 18 · 2023: 25 · 2022: 17 · 2021: 19 · 2020: 8
FWCI
0.89
Type
journal article
Language
en
Open access
closed
Locations
  • Cancer Letters (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Physical Sciences › Engineering › Biomedical Engineering › Ultrasound and Hyperthermia Applications
  • Physical Sciences › Engineering › Biomedical Engineering › Photoacoustic and Ultrasonic Imaging
Keywords
cancer, ultrasound molecular imaging, nanomaterials, microbubbles, structure-function relationship, tumor diagnosis, clinical translation
MeSH terms
Theranostic Nanomedicine, Animals, Antineoplastic Agents, Combined Modality Therapy, Contrast Media, Disease Models, Animal, Humans, Immunotherapy, Neoplasms, Ultrasonography, Ultrasonic Therapy, Microbubbles, Nanoparticles, Photoacoustic Techniques, Multimodal Imaging

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