Nitric oxide in myocardial ischemia/reperfusion injury

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

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Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms

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The Late Phase of Preconditioning

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Effects of Angiotensin II Infusion on the Expression and Function of NAD(P)H Oxidase and Components of Nitric Oxide/cGMP Signaling

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Nitric oxide metabolism and breakdown

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Cardioprotective Function of Inducible Nitric Oxide Synthase and Role of Nitric Oxide in Myocardial Ischemia and Preconditioning: an Overview of a Decade of Research

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Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

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Measurement of Nitric Oxide and Peroxynitrite Generation in the Postischemic Heart

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Synthesis of nitric oxide from l -arginine by neutrophils. Release and interaction with superoxide anion

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Emerging role of nitrite in myocardial protection

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Diosgenin-induced protection against myocardial ischaemia-reperfusion injury is mediated by mitochondrial K ATP channels in a rat model

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KRT1 gene silencing ameliorates myocardial ischemia–reperfusion injury via the activation of the Notch signaling pathway in mouse models

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The multi-faceted behavior of nitric oxide in vascular “inflammation”: catchy terminology or true phenomenon?

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Nitric Oxide Signaling in Cardiovascular Physiology and Pathology: Mechanisms, Dysregulation, and Therapeutic Frontiers

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Ultrasound-Induced Destruction of Nitric Oxide–Loaded Microbubbles in the Treatment of Thrombus and Ischemia–Reperfusion Injury

Liang, Z., Chen, H., Gong, X., Shi, B., Lin, L., Tao, F.-Y., Wu, Q., Fang, M., Li, H., Lu, C., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.745693 · Cited by 26

Protective Effects of Shenfu Injection against Myocardial Ischemia–Reperfusion Injury via Activation of eNOS in Rats

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Dual modulation of nitric oxide production in the heart during ischaemia/reperfusion injury and inflammation

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Post-resuscitation reperfusion injury: Comparison of periodic Gz acceleration versus Thumper CPR

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Role of glycogen synthase kinase 3β in protective effect of propofol against hepatic ischemia–reperfusion injury

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Sevoflurane exerts protective effects on liver ischemia/reperfusion injury by regulating NFKB3 expression via miR‑9‑5p

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Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure

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Hypercapnia prevents neovascularization via nitrative stress

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Pharmacodynamic Hybrids Coupling Established Cardiovascular Mechanisms of Action with Additional Nitric Oxide Releasing Properties

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The Protective Effects of Alpha-Lipoic Acid and Coenzyme Q10Combination on Ovarian Ischemia-Reperfusion Injury: An Experimental Study

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The cardioprotective effects of (-)-Epicatechin are mediated through arginase activity inhibition in a murine model of ischemia/reperfusion

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Liposomal tetrahydrobiopterin preserves eNOS coupling in the post-ischemic heart conferring in vivo cardioprotection

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Nitric oxide and prostacyclin pathways: An integrated mechanism that limits myocardial infarction progression in anaesthetized rats

Rossoni, G., Manfredi, B., DEGENNAROCOLONNA, V., Brini, A. T., Polvani, G., CLEMENT, M., & Berti, F. (2006) · Pharmacological Research · doi:10.1016/j.phrs.2006.01.004 · Cited by 25

Curcuma Oil Reduces Endothelial Cell-mediated Inflammation in Postmyocardial Ischemia/Reperfusion in Rats

Manhas, A., Khanna, V., Prakash, P., Goyal, D., Malasoni, R., Naqvi, A., Dwivedi, A. K., Dikshit, M., & Jagavelu, K. (2014) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000110 · Cited by 24

Effects of Ischemic Postconditioning on the Hemodynamic Parameters and Heart Nitric Oxide Levels of Hypothyroid Rats

Jeddi, S., Zaman, J., & Ghasemi, A. (2014) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20140181 · Cited by 23

Synthetic high density lipoproteins for the treatment of myocardial ischemia/reperfusion injury

Calabresi, L., Gomaraschi, M., Rossoni, G., & Franceschini, G. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2006.01.003 · Cited by 23

Different roles of nitric oxide synthase isoforms in cardiopulmonary resuscitation in pigs

Wu, D., Bassuk, J. A., Arias, J., Kurlansky, P. A., Lozano, H. F., Lamas, G. A., & Adams, J. A. (2007) · Resuscitation · doi:10.1016/j.resuscitation.2006.07.026 · Cited by 23

Cardioprotection by Regular Ethanol Consumption: Potential Mechanisms and Clinical Application

Miyamae, M., Kaneda, K., Domae, N., & Figueredo, V. M. (2010) · Current Drug Abuse Reviews · doi:10.2174/1874473711003010039 · Cited by 22

Nitric oxide and its circulating NOx metabolites, their role in human body functioning and cardiovascular death risk prediction (part I)

Gumanova, N. G. (2021) · Russian Journal of Preventive Medicine · doi:10.17116/profmed202124091102 · Cited by 23

HNO Protects the Myocardium against Reperfusion Injury, Inhibiting the mPTP Opening via PKCε Activation

Mancardi, D., Pagliaro, P., Ridnour, L. A., Tocchetti, C. G., Miranda, K. M., Juhaszova, M., Sollott, S. J., Wink, D. A., & Paolocci, N. (2022) · Antioxidants · doi:10.3390/antiox11020382 · Cited by 24

In Vivo Cardioprotection by Pitavastatin From Ischemic-reperfusion Injury Through Suppression of IKK/NF-κB and Upregulation of pAkt–e-NOS

Malik, S., Sharma, A. K., Bharti, S., Nepal, S., Bhatia, J., Nag, T. C., Narang, R., & Arya, D. S. (2011) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e31822002a6 · Cited by 22

Antioxidation Role of Different Lateral Stellate Ganglion Block in Isoproterenol-Induced Acute Myocardial Ischemia in Rats

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Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial

Schlapbach, L. J., Horton, S., Long, D. A., Beca, J., Erickson, S. J., Festa, M., d’Udekem, Y., Alphonso, N., Winlaw, D. S., Johnson, K. E., et al. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-026664 · Cited by 22

Periodic acceleration (pGz) acutely increases endothelial and neuronal nitric oxide synthase expression in endomyocardium of normal swine

Adams, J. A., Wu, H., Bassuk, J. A., Arias, J., Uryash, A., & Kurlansky, P. A. (2008) · Peptides · doi:10.1016/j.peptides.2008.10.014 · Cited by 22

In Vivo Reduction of Reperfusion Injury to the Heart with Apelin-12 Peptide in Rats

Pisarenko, O. I., Serebryakova, L. I., Pelogeykina, Y. A., Studneva, I. M., Khatri, D. N., Tskitishvili, O. V., Беспалова, Ж. Д., Азьмуко, А. А., Sidorova, M. V., & Palkeeva, M. E. (2011) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-011-1459-9 · Cited by 22

Ischemia and reperfusion: the endothelial perspective. A radical view.

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Clinical Applications for Gasotransmitters in the Cardiovascular System: Are We There Yet?

Arrigo, E., Comità, S., Pagliaro, P., Penna, C. R. R., & Mancardi, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512480 · Cited by 21

The GTN patch: a simple and effective new approach to cardioprotection?

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Implications of Oxidative and Nitrosative Post-Translational Modifications in Therapeutic Strategies against Reperfusion Damage

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Cardiovascular Properties of a Nitric Oxide Releasing Rofecoxib Analogue: Beneficial Anti‐hypertensive Activity and Enhanced Recovery in an Ischemic Reperfusion Injury Model

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Propofol attenuates angiotensin II-induced apoptosis in human coronary artery endothelial cells

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Drugs mediating myocardial protection

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Cavin-1 deficiency modifies myocardial and coronary function, stretch responses and ischaemic tolerance: roles of NOS over-activity

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Ultrasound-Targeted Microbubble Cavitation with Sodium Nitrite Synergistically Enhances Nitric Oxide Production and Microvascular Perfusion

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Targets of cGMP/cGKI in Cardiac Myocytes

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Mitochondrial mechanisms by which gasotransmitters (H2S, NO and CO) protect cardiovascular system against hypoxia

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Heat shock proteins, end effectors of myocardium ischemic preconditioning?

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NO Signaling in the Cardiovascular System and Exercise

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High-density lipoproteins in stroke.

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Oxygen tension, H2S, and NO bioavailability: is there an interaction?

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Evidence for enhanced eNOS function in coronary microvessels during the second window of protection

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Protein S-nitrosylation: a role of nitric oxide signaling in cardiac ischemic preconditioning.

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S-Nitrosylation Proteome Profile of Peripheral Blood Mononuclear Cells in Human Heart Failure

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Antioxidative and Antiapoptotic Effects of Delta-Opioid Peptide [D-Ala2, D-Leu5] Enkephalin on Spinal Cord Ischemia-Reperfusion Injury in Rabbits

Fu, D., Liu, H., Li, S., Chen, L., & Yao, J. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00603 · Cited by 18

The effects of carvedilol on cardiac structural remodeling: The role of endogenous nitric oxide in the activity of carvedilol

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Cardioprotection Against Ischemia/Reperfusion Injury and Chromogranin ADerived Peptides

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Nitric oxide releasing-dendrimers: an overview

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The role of reactive free radicals in ischemic preconditioning--clinical and evolutionary implications.

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Efficacy of ischaemic preconditioning in the eNOS overexpressed working mouse heart model

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Simultaneous, real-time measurement of nitric oxide and oxygen dynamics during cardiac ischemia–reperfusion of the rat utilizing sol–gel-derived electrochemical microsensors

Kang, S. W., Kim, O. K., Seo, B., Lee, S. H., Quan, F., Shin, J. H., Lee, G., & Park, H. (2013) · Analytica Chimica Acta · doi:10.1016/j.aca.2013.09.029 · Cited by 17

Nitric Oxide Pathways in Toxic Responses

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An Integrated Pharmacokinetic Study of an Acanthopanax senticosus Extract Preparation by Combination of Virtual Screening, Systems Pharmacology, and Multi-Component Pharmacokinetics in Rats

Shi, P., Xie, Y., Xie, R., Lin, Z., Yao, H., & Wu, S. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01295 · Cited by 16

The impact of exogenous nitric oxide during cardiopulmonary bypass for cardiac surgery

Loughlin, J. B. M., Browne, L., & Hinchion, J. (2021) · Perfusion · doi:10.1177/02676591211014821 · Cited by 16

Redox environment metabolomic evaluation (REME) of the heart after myocardial ischemia/reperfusion injury

Cai, W.-B., Zhao, Y., Liu, L., Cheng, Q., Wang, J., Shi, X., Liu, Y. Z., Qiao, X., Zhu, Y., Chen, C., et al. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.06.033 · Cited by 16

Role of tetrahydrobiopterin in resistance to myocardial ischemia in Brown Norway and Dahl S rats

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The effects of nitric oxide-oxidase and putative glutathione-peroxidase activities of ceruloplasmin on the viability of cardiomyocytes exposed to hydrogen peroxide

Paradis, M., Gagné, J., Mateescu, M., & Paquin, J. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.09.030 · Cited by 16

Coronary response to diadenosine pentaphosphate after ischaemia-reperfusion in the isolated rat heart

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Nitric oxide inhibits T cell adhesion and migration by down-regulation of β1-integrin expression in immunologically liver-injured mice

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Serial measurements of whole blood nitrite in an intensive care setting

Kehmeier, E. S., Kropp, M., Kleinbongard, P., Lauer, T., Balzer, J., Merx, M. W., Heusch, G., Kelm, M., Lepper, W., & Rassaf, T. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.02.014 · Cited by 16

Organic Nanoparticles in Progressing Cardiovascular Disease Treatment and Diagnosis

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Effect of melatonin and vitamin C on expression of endothelial NOS in heart of chronic alcoholic rats

Sönmez, M., Narin, F., Akkuş, D., & Özdamar, S. (2009) · Toxicology and Industrial Health · doi:10.1177/0748233709106444 · Cited by 15

Calcitonin Gene-Related Peptide Improves Hypoxia-Induced Inflammation and Apoptosis via Nitric Oxide in H9c2 Cardiomyoblast Cells

Duan, L., Lei, H., Zhang, Y., Wan, B., Chang, J., Feng, Q., & Huang, W. (2015) · Cardiology · doi:10.1159/000439123 · Cited by 15

Hypoxia Inducible Factor-1 Improves the Actions of Nitric Oxide and Natriuretic Peptides after Simulated Ischemia-Reperfusion

Luciano, J. A., Tan, T., Zhang, Q., Huang, E. S., Scholz, P., & Weiss, H. R. (2008) · Cellular Physiology and Biochemistry · doi:10.1159/000129634 · Cited by 15

Tetrahydrobiopterin Protects against Radiation-induced Growth Inhibition in H9c2 Cardiomyocytes

Zhang, Z., Li, Y., Li, R., Zhang, A., Shang, B., Yu, J., & Xie, X. (2016) · Chinese Medical Journal · doi:10.4103/0366-6999.193455 · Cited by 15

Connexins and Nitric Oxide Inside and Outside Mitochondria: Significance for Cardiac Protection and Adaptation

Shvedova, M., Anfinogenova, Y., Popov, S. V., & Atochin, D. N. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00479 · Cited by 15

Role of nNOS in Cardiac Ischemia-Reperfusion Injury

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Periodic acceleration (pGz) CPR in a swine model of asphyxia induced cardiac arrest

Adams, J. A., Bassuk, J. A., Arias, J., Wu, H., Jorapur, V., Lamas, G. A., & Kurlansky, P. A. (2008) · Resuscitation · doi:10.1016/j.resuscitation.2007.10.018 · Cited by 15

Transdermally administered nitric oxide by application of acidified nitrite increases blood flow in rat epigastric island skin flaps

Gribbe, Ö., Gustafsson, L. E., & Wiklund, P. N. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.09.032 · Cited by 15

Myocardial Ischemia

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Nitrogen oxide and its circulating NOx metabolites, their role in human body functioning and cardiovascular death risk prediction (Part II)

Gumanova, N. G. (2021) · Russian Journal of Preventive Medicine · doi:10.17116/profmed202124101119 · Cited by 14

Machine perfusion of donor heart with normothermic blood versus hypothermic HTK in preserving coronary endothelium in a porcine model of DCD

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Endothelial Nitric Oxide Synthase Mediates the First and Inducible Nitric Oxide Synthase Mediates the Second Window of Desflurane-Induced Preconditioning

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Low concentrations of an nitric oxide-donor combined with a liposoluble antioxidant compound enhance protection against reperfusion injury in isolated rat hearts.

Rastaldo, R., Cappello, S., Folino, A., Stilo, A. D., Chegaev, K. Y., Tritto, I., Pagliaro, P., & Losano, G. A. (2010) · PubMed · Cited by 14

The renaissance of nitric oxide: from improvement of stability to enhancement of endocytosis

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