Prevalence of the metabolic syndrome using the Third Report of the National Cholesterol Educational Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III) and the modified ATP III definitions for Japanese and Mongolians
Abstract
Background A clustering of insulin resistance, hypertension, and dyslipidemia has been labeled as metabolic syndrome. Asians have a lower frequency of obesity than do Caucasians but have an increasing tendency toward metabolic syndrome.Methods We conducted a cross-sectional study of individuals aged 30-60 years. We analyzed the health data of 596 Japanese and Mongolians for metabolic syndrome based on the Third Report of the National Cholesterol Educational Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III) definition and the three modified ATP III definitions.Results The prevalence of metabolic syndrome using ATP III criteria was 6% for the Japanese and 12% for the Mongolians, a remarkable lower prevalence relative to the reported prevalence in the United States. With the exception of visceral obesity, the prevalences of individual metabolic abnormalities within each of the two Asian groups were similar to each other and to reported rates of prevalence in the United States.Conclusions A universal metabolic syndrome definition is inappropriate for comparisons of metabolic syndrome among Asian ethnic groups. We believe that the ATP III index for visceral obesity should be adjusted for Asian populations.
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Some populations, including those from South Asia, China, Japan, and other Asian countries, are predisposed to insulin resistance, metabolic syndrome, and type 2 diabetes with only moderate increases in waist circumference.
“In addition, some populations are predisposed to insulin resistance, metabolic syndrome, and type 2 diabetes mellitus, with only moderate increases in waist circumference (ie, populations from South Asia, China, Japan, and other Asian countries).127,130,131,142”
From Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement (2005) · cites this paper as [127]
When applying ATP III criteria in Asian countries, lower waist circumferences as defined by IDF for these populations appear appropriate as one risk factor.
“At the same time, when applying ATP III criteria in Asian countries, lower waist circumferences, as defined by IDF for these populations, appear to be appropriate as 1 risk factor.127,130,131,142”
From Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement (2005) · cites this paper as [127]
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- Authors
- Enkhmaa, B., Shiwaku, K., Anuurad, E., Nogi, A., Kitajima, K., Yamasaki, M., Oyunsuren, T., & Yamane, Y.
- Affiliations
- Shimane University (JP)
- Yamaguchi Prefectural University (JP)
- Mongolian Academy of Sciences (MN)
- Corresponding author
- Shiwaku, Kuninori
- Venue
- Clinica Chimica Acta
- Publisher
- Elsevier BV
- Published
- 2005-02
- Volume
- 352
- Issue
- 1-2
- Pages
- 105-113
- ISSN
- 0009-8981 (ISSN-L)
- OpenAlex
- W1963773040
- Cited by
- 61
- References
- 32
- Citations by year
- 2025: 1 · 2023: 3 · 2021: 2 · 2020: 3 · 2019: 4 · 2018: 1 · 2017: 1 · 2016: 6 · 2015: 4 · 2014: 5 · 2013: 1 · 2012: 6
- FWCI
- 3.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinica Chimica Acta (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Keywords
- metabolic syndrome, prevalence, NCEP ATP III criteria, Japanese, Mongolian language, Asian populations, visceral obesity, insulin resistance, hypertension, dyslipidemia
- MeSH terms
- Adult, Cross-Sectional Studies, Female, Humans, Hypercholesterolemia, Male, Middle Aged, Prevalence, Practice Guidelines as Topic, Metabolic Syndrome, Asian People
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