GOLM1 modulates EGFR/RTK cell-surface recycling to drive hepatocellular carcinoma metastasis

Ye, Qing-Hai, Zhu, Wen-Wei, Zhang, Ju-Bo, Qin, Yi, Lu, Ming, Lin, Guo-Ling, Guo, Lei, Zhang, Bo +12 more·2016·Cancer Cell

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    Bin Wang, Xing Sun, Kejian Huang, Li-Sheng Zhou, Zhengjun Qiu · 2021 · World Journal of Gastroenterology
  2. Research progress on GP73 in malignant tumors
    Rong Liang, Ziyu Liu, Xuemin Piao, Mingtang Zuo, Jinyan Zhang, Zhihui Liu, Yongqiang Li, Yan Lin · 2018 · OncoTargets and Therapy
  3. GOLM1 silencing inhibits the proliferation and motility of human glioblastoma cells via the Wnt/β-catenin signaling pathway
    Xiang Ding, Gang Deng, Junhui Liu, Baohui Liu, Fanen Yuan, Xue Yang, Qianxue Chen · 2019 · Brain Research
  4. Stepwise crosstalk between aberrant Nf1, Tp53 and Rb signalling pathways induces gliomagenesis in zebrafish
    Juanjuan Luo, Pei Liu, Chunjiao Lu, Wan-Ping Bian, Dongsheng Su, Chenchen Zhu, Shaolin Xie, Yihang Pan, Ningning Li, Wei Cui et al. · 2020 · Brain
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  6. Deciphering a profiling based on multiple post-translational modifications functionally associated regulatory patterns and therapeutic opportunities in human hepatocellular carcinoma
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  7. Supervillin promotes tumor angiogenesis in liver cancer
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  8. Recent advances of GOLM1 in hepatocellular carcinoma
    Jiuliang Yan, Binghai Zhou, Hui Li, Lei Guo, Qing‐Hai Ye · 2020 · Hepatic Oncology
  9. Identification of a novel Calpain-2-SRC feed-back loop as necessity for β-Catenin accumulation and signaling activation in hepatocellular carcinoma
    Xiaolu Ma, Keyu Zhu, Yueda Chen, Weiguo Tang, Suhong Xie, Hui Zheng, Ying Tong, Yanchun Wang, Ning Ren, Lin Guo et al. · 2022 · Oncogene
  10. PELI1 and EGFR cooperate to promote breast cancer metastasis
    Jie Qi, Guangsen Xu, Xiaoxia Wu, Chunhua Lu, Yuemao Shen, Baobing Zhao · 2023 · Oncogenesis
  11. Overexpression of ARID4B predicts poor survival in patients with hepatocellular carcinoma
    Rongchang Wang, Zheng Yu, Fan Chen, Chunlian Liao, Qian Wang, Xiaohui Huang · 2017 · Human Pathology
  12. Immunological Significance of Prognostic DNA Methylation Sites in Hepatocellular Carcinoma
    Qianhui Xu, Yuanbo Hu, Shaohuai Chen, Yulun Zhu, Siwei Li, Feng Shen, Yifan Guo, Tao Sun, Xiaoyu Chen, Jinpeng Jiang et al. · 2021 · Frontiers in Molecular Biosciences
  13. GP73, a novel TGF-β target gene, provides selective regulation on Smad and non-Smad signaling pathways
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  14. Suppression of GOLM1 by EGCG through HGF/HGFR/AKT/GSK-3β/β-catenin/c-Myc signaling pathway inhibits cell migration of MDA-MB-231
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  15. Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis
    Tengfei Liu, Binbin Liu, Yiting Liu, Xingzhi Feng, Xuefei Jiang, Jiahui Long, Qianling Gao, Zihuan Yang · 2021 · Cancer Cell International
  16. Identification of ZBTB9 as a potential therapeutic target against dysregulation of tumor cells proliferation and a novel biomarker in Liver Hepatocellular Carcinoma
    Zhenshan Zhang, Leilei Wu, Juan Li, Jiayan Chen, Yu Qi, Hui Yao, Yaping Xu, Liang Liu · 2022 · Journal of Translational Medicine
  17. Golgi-protein 73 facilitates vimentin polymerization in hepatocellular carcinoma
    Xinyang Hu, Shijin Yuan, Sining Zhou, Ting Sun, Chaoqun Wang, Shilong Ying, Heping Zhu, Jingfeng Luo, Hongchuan Jin, Yiming Liu · 2023 · International Journal of Biological Sciences
  18. Association between blood lipid levels and the risk of liver cancer: a systematic review and meta-analysis
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  19. Coordinated ASBT and EGFR Mechanisms for Optimized Liraglutide Nanoformulation Absorption in the GI Tract
    Seho Kweon, Seong Jin Park, Ha Kyeong Lee, Seo Hee Kang, Kwan-Young Chang, Jeong Uk Choi, Jooho Park, Jung‐Hyun Shim, Jin Woo Park, Youngro Byun · 2024 · International Journal of Nanomedicine
  20. Golgi apparatus targeted therapy in cancer: Are we there yet?
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  21. GOLM1-regulated EGFR/RTK recycling is a novel target for combating HCC metastasis
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  22. Research progress on the role of cholesterol in hepatocellular carcinoma
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  23. Molecular subtype identification and signature construction based on Golgi apparatus-related genes for better prediction prognosis and immunotherapy response in hepatocellular carcinoma
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  24. Xmrks the Spot: Fish Models for Investigating Epidermal Growth Factor Receptor Signaling in Cancer Research
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  25. RAB22A sorts epithelial growth factor receptor (EGFR) from early endosomes to recycling endosomes for microvesicles release
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  26. GOLM1 depletion modifies cellular sphingolipid metabolism and adversely affects cell growth
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  27. AGPAT4 targeted covalent inhibitor potentiates targeted therapy to overcome cancer cell plasticity in hepatocellular carcinoma mouse models
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  30. GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in metabolic dysfunction-associated steatohepatitis livers
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  31. Identification of potential diagnostic and prognostic biomarkers for prostate cancer
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  32. Associating Preoperative MRI Features and Gene Expression Signatures of Early-stage Hepatocellular Carcinoma Patients using Machine Learning
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  33. Golgi Phosphoprotein 2 Is a Novel Regulator of IL-12 Production and Macrophage Polarization
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  34. Trafficking of Adhesion and Growth Factor Receptors and Their Effector Kinases
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  35. Canopy Homolog 2 Expression Predicts Poor Prognosis in Hepatocellular Carcinoma with Tumor Hemorrhage
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  36. A meta-analysis of the prognostic significance of Golgi protein 73 in hepatocellular carcinoma in Chinese patients
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  37. Endocytic evasion confers resistance to antibody-drug conjugates therapy in cancer
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  38. GOLM1 Promotes Pulmonary Fibrosis through Upregulation of NEAT1
    Yani Wang, Danjing Hu, Lin‐Yan Wan, Shuhui Yang, Song Liu, Zixi Wang, Jie Li, Jia Li, Zhoude Zheng, Chongsheng Cheng et al. · 2023 · American Journal of Respiratory Cell and Molecular Biology
  39. GOLM1 Promotes Epithelial-Mesenchymal Transition by Activating TGFβ1/Smad2 Signaling in Prostate Cancer
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  40. The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression
    Lan Zhen, Min Min, Xinglin Mo, Guilin Zhao, Huilong Li, Muyi Liu, Luming Wan, Xiaopan Yang, Linfei Huang, Yanhong Zhang et al. · 2025 · Journal of Advanced Research
  41. Exosomes Derived from microRNA-27a-3p Overexpressing Mesenchymal Stem Cells Inhibit the Progression of Liver Cancer through Suppression of Golgi Membrane Protein 1
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  42. DDX3 suppresses hepatocellular carcinoma progression through modulating the secretion and composition of exosome.
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  43. CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR
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  44. TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport
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  45. GP73 blockade alleviates abnormal glucose homeostasis in diabetic mice
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  46. EPS8L3 promotes hepatocellular carcinoma proliferation and metastasis by modulating EGFR dimerization and internalization.
    Zefeng Xuan, Long Zhao, Zequn Li, Wenfeng Song, Jun Chen, Jian Chen, Hao Chen, Guangyuan Song, Cheng Jin, Mengqiao Zhou et al. · 2020 · PubMed Central
  47. GOLM1 facilitates human colorectal cancer progression and metastasis via activating the AKT/GSK3β/EMT axis
    Zonglei Mao, Yong Gui Wu, Pingan Yao, Chungen Xing · 2023 · Neoplasma
  48. A Systems Approach to Interrogate Gene Expression Patterns in African American Men Presenting with Clinically Localized Prostate Cancer
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  49. ACOT12-mediated acetyl-CoA hydrolysis suppresses intrahepatic cholangiocarcinoma metastasis by inhibiting epithelial-mesenchymal transition
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  50. Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability
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  51. GOLM1 dictates acquired Lenvatinib resistance by a GOLM1-CSN5 positive feedback loop upon EGFR signaling activation in hepatocellular carcinoma
    Peiyi Xie, Mengyuan Wu, Hui Wang, Bo Zhang, Zihao Zhang, Jiuliang Yan, Mincheng Yu, Qiang Yu, Yufei Zhao, Da Huang et al. · 2024 · Oncogene
  52. PTEN deficiency potentiates HBV-associated liver cancer development through augmented GP73/GOLM1
    Fuqiang Huang, Jing Guo, Na Zhao, Mengjie Hou, Xiaochen Gai, Shuhui Yang, Pei Cai, Yanan Wang, Qian Ma, Qi Zhao et al. · 2024 · Journal of Translational Medicine
  53. Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma
    Guodong Chen, Peizhong Kong, Miaomiao Yang, Wanglai Hu, Kevin M. Prise, K.N. Yu, Shujun Cui, Feng Qin, Gang Meng, Waleed Abdelbagi Almahi et al. · 2021 · International Journal of Radiation Oncology*Biology*Physics
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    Pingping Feng, Xinyang Hu, Sining Zhou, Xianyong Liu, Linghui Zeng, Yiming Liu · 2025 · Frontiers in Immunology
  55. GOLM1 predicts poor prognosis of patients with NSCLC and is associated with the proliferation and chemo‐sensitivity of cisplatin in NSCLC cells: bioinformatics analysis and laboratory validation
    Mei Zhao, Xuelian Li, Xin Chen · 2021 · Journal of Bioenergetics and Biomembranes
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