Intertumoral Heterogeneity within Medulloblastoma Subgroups

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2. Molecular markers and potential therapeutic targets in non-WNT/non-SHH (group 3 and group 4) medulloblastomas
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3. Differential patterns of metastatic dissemination across medulloblastoma subgroups
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4. Updates on Management of Adult Medulloblastoma
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5. RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression
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6. Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation
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7. ctDNA-Based Liquid Biopsy of Cerebrospinal Fluid in Brain Cancer
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8. The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma
   Lospinoso Severini, Ludovica, Ghirga, Francesca, Bufalieri, Francesca, Quaglio, Deborah, Infante, Paola, Di Marcotullio, Lucia · 2020 · Expert Opinion on Therapeutic Targets
9. Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma
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12. Autophagy in cancers including brain tumors: role of MicroRNAs
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13. Medulloblastoma in the Modern Era: Review of Contemporary Trials, Molecular Advances, and Updates in Management
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14. Childhood Medulloblastoma: Current Therapies, Emerging Molecular Landscape and Newer Therapeutic Insights
    Soumen Khatua, Anne Song, Divyaswathi Citla Sridhar, Stephen C. Mack · 2018 · Current Neuropharmacology
15. Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
    Matko Čančer, Sonja Hutter, Karl O. Holmberg, Gabriela Rosén, Anders Sundström, Jignesh K. Tailor, Tobias Bergström, Alexandra Garancher, Magnus Essand, Robert J. Wechsler‐Reya et al. · 2019 · Cell stem cell
16. B7–H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric central nervous system Tumors
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17. Subgroup-specific prognostic signaling and metabolic pathways in pediatric medulloblastoma
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18. Advancing CNS tumor diagnostics with expanded DNA methylation-based classification
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19. Heterozygous BRCA1 and BRCA2 and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents With Cancer
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20. Poliovirus Receptor (CD155) Expression in Pediatric Brain Tumors Mediates Oncolysis of Medulloblastoma and Pleomorphic Xanthoastrocytoma
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21. Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma
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22. Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination
    Vahan Martirosian, Krutika Deshpande, Hao Zhou, Keyue Shen, Kyle S. Smith, Paul A. Northcott, Michelle P. Lin, Vazgen Stepanosyan, Diganta Das, Ján Remšík et al. · 2021 · Cell Reports
23. Medulloblastoma: Molecular understanding, treatment evolution, and new developments
    Liu, Xiaohua, Ding, Chunyong, Tan, Wenfu, Zhang, Ao · 2020 · Pharmacology & Therapeutics
24. Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma
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25. Molecular correlates of cerebellar mutism syndrome in medulloblastoma
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26. Incremental prognostic value and underlying biological pathways of radiomics patterns in medulloblastoma
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27. Clinical and mutational profiles of adult medulloblastoma groups
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28. Prognostic relevance of clinical and molecular risk factors in children with high-risk medulloblastoma treated in the phase II trial PNET HR+5
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29. Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity
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30. Recent Advances in Pediatric Medulloblastoma
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31. MYC Drives Group 3 Medulloblastoma through Transformation of Sox2+ Astrocyte Progenitor Cells
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32. RETRACTED ARTICLE: Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis
    Zaili Luo, Mingyang Xia, Wei Shi, Chuntao Zhao, Jiajia Wang, Dazhuan Eric Xin, Xinran Dong, Yu Xiong, Feng Zhang, Kalen Berry et al. · 2022 · Nature · Retracted
33. Proteomic analysis of Medulloblastoma reveals functional biology with translational potential
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34. Picosecond Infrared Laser Desorption Mass Spectrometry Identifies Medulloblastoma Subgroups on Intrasurgical Timescales
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35. The molecular biology of medulloblastoma metastasis
    Randy Van Ommeren, Livia Garzia, Borja Holgado, Vijay Ramaswamy, Michael D. Taylor · 2019 · Brain Pathology
36. Multifaceted microglia — key players in primary brain tumour heterogeneity
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37. Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial
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38. Artificial Intelligence for Precision Oncology
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39. Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation
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40. Nuclear Factor One X in Development and Disease
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41. Developmental origins and oncogenic pathways in malignant brain tumors
    Qing Richard Lu, Lily Qian, Xianyao Zhou · 2019 · Wiley Interdisciplinary Reviews Developmental Biology
42. Current medulloblastoma subgroup specific clinical trials
    Eric M. Thompson, David M. Ashley, Daniel B. Landi · 2020 · Translational Pediatrics
43. Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse
    Stacey Richardson, Rebecca M. Hill, Christopher Kui, Janet C. Lindsey, Yura Grabovksa, Claire Keeling, Louise I. Pease, Matthew Bashton, Stephen Crosier, Maria Vinci et al. · 2021 · Neuro-Oncology
44. Mapping pediatric brain tumors to their origins in the developing cerebellum
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45. Invited Review: DNA methylation‐based classification of paediatric brain tumours
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46. Genomics of adult and pediatric solid tumors.
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47. Immunotherapy for Medulloblastoma: Current Perspectives
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48. Wnt activation as a therapeutic strategy in medulloblastoma
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49. Integrative analysis of the inter-tumoral heterogeneity of triple-negative breast cancer
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50. Modeling pediatric medulloblastoma
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51. Advanced Neuroimaging Approaches to Pediatric Brain Tumors
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52. cIMPACT-NOW update 9: Recommendations on utilization of genome-wide DNA methylation profiling for central nervous system tumor diagnostics
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53. Molecular Stratification of Medulloblastoma: Clinical Outcomes and Therapeutic Interventions
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54. Improved Long-Term Survival of Patients with Recurrent Medulloblastoma Treated with a “MEMMAT-like” Metronomic Antiangiogenic Approach
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55. Multi-omics and artificial intelligence predict clinical outcomes of immunotherapy in non-small cell lung cancer patients
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56. MRI Characteristics of Primary Tumors and Metastatic Lesions in Molecular Subgroups of Pediatric Medulloblastoma: A Single-Center Study
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57. TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma
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59. DNA methylation profiling is a method of choice for molecular verification of pediatric WNT-activated medulloblastomas
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61. Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration
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62. Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma
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64. Inhibition of the amino‐acid transporter LAT1 demonstrates anti‐neoplastic activity in medulloblastoma
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65. Autocrine IL-6/STAT3 signaling aids development of acquired drug resistance in Group 3 medulloblastoma
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66. 3D spheroid models of paediatric SHH medulloblastoma mimic tumour biology, drug response and metastatic dissemination
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67. Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma
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68. Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization
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69. Single-cell spatial transcriptomic analysis reveals common and divergent features of developing postnatal granule cerebellar cells and medulloblastoma
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70. MRI features as a helpful tool to predict the molecular subgroups of medulloblastoma: state of the art
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71. Impact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis
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72. Dual BRD4 and AURKA Inhibition Is Synergistic against MYCN-Amplified and Nonamplified Neuroblastoma
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73. Engineered hydrogels for brain tumor culture and therapy
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74. An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate
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76. Targeting MYCN in Molecularly Defined Malignant Brain Tumors
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77. A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy
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80. Neurotrophin Signaling in Medulloblastoma
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81. MEVITEM—a phase I/II trial of vismodegib + temozolomide vs temozolomide in patients with recurrent/refractory medulloblastoma with Sonic Hedgehog pathway activation
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84. Principles of tumorigenesis and emerging molecular drivers of SHH ‐activated medulloblastomas
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85. Biallelic PTCH1 Inactivation Is a Dominant Genomic Change in Sporadic Keratocystic Odontogenic Tumors
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86. Effective inhibition of MYC-amplified group 3 medulloblastoma by FACT-targeted curaxin drug CBL0137
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87. Epigenomics and immunotherapeutic advances in pediatric brain tumors
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88. Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling
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90. Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosis
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92. Computational Analysis of Phosphoproteomics Data in Multi‐Omics Cancer Studies
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93. In Vivo and Ex Vivo Pediatric Brain Tumor Models: An Overview
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94. Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma
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95. Molecular determinants of medulloblastoma metastasis and leptomeningeal dissemination
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96. Molecular and clinical heterogeneity within MYC -family amplified medulloblastoma is associated with survival outcomes: A multicenter cohort study
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97. Distinctive localization and MRI features correlate of molecular subgroups in adult medulloblastoma
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98. Medulloblastoma in the Molecular Era
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99. BMI1 is a therapeutic target in recurrent medulloblastoma
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