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Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102

Brashears, C. B., Prudner, B. C., Rathore, R., Caldwell, K. E., Dehner, C. A., Buchanan, J. L., Lange, S. E. S., Poulin, N., Sehn, J. K., Roszik, J., et al. (2022) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-22-0470 · Cited by 32

Carnosol Induces p38-Mediated ER Stress Response and Autophagy in Human Breast Cancer Cells

Alsamri, H., Alneyadi, A. H., Muhammad, K., Ayoub, M. A., Eid, A. H., & Iratni, R. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.911615 · Cited by 32

Tumor killing by a dietary curcumin mono-carbonyl analog that works as a selective ROS generator via TrxR inhibition

Liu, X., Cui, H., Li, M., Chai, Z.-H., Wang, H., Jin, X., Dai, F., Liu, Y., & Zhou, B. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.115191 · Cited by 32

Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer CellsIn Vitroand in a MIAPaca2 Xenograft Animal Model

Stan, S. D., Singh, S. V., Whitcomb, D. C., & Brand, R. E. (2013) · Nutrition and Cancer · doi:10.1080/01635581.2013.795979 · Cited by 32

Physapubescin B Exhibits Potent Activity against Human Prostate Cancer In Vitro and In Vivo

Ding, W., Hu, Z., Zhang, Z., Ma, Q., Tang, H., & Ma, Z. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b03045 · Cited by 32

Moonlighting Metabolic Enzymes in Cancer: New Perspectives on the Redox Code

Jiang, J., Peng, L., Wang, K., & Huang, C. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8123 · Cited by 31

Plasma membrane anchored nanosensor for quantifying endogenous production of H2O2 in living cells

Hosogi, S., Marunaka, Y., Ashihara, E., Yamada, T., Sumino, A., Tanaka, H., & Puppulin, L. (2021) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2021.113077 · Cited by 32

Hydroxyethyl starch stabilized copper-diethyldithiocarbamate nanocrystals for cancer therapy

Xiao, C., Li, J., Wang, X., Li, S., Xu, C., Zhang, Z., Hua, A., Ding, Z., Zhang, B., Yang, X., et al. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.02.043 · Cited by 33

Natural Product-Derived Antitumor Compound Phenethyl Isothiocyanate Inhibits mTORC1 Activity via TSC2

Cavell, B. E., Alwi, S. S. S., Donlevy, A. M., Proud, C. G., & Packham, G. (2012) · Journal of Natural Products · doi:10.1021/np300049b · Cited by 31

Insulin receptor substrate-1 prevents autophagy-dependent cell death caused by oxidative stress in mouse NIH/3T3 cells

Chan, S. H., Kikkawa, U., Matsuzaki, H., Chen, J.-H., & Chang, W. (2012) · Journal of Biomedical Science · doi:10.1186/1423-0127-19-64 · Cited by 31

Melatonin and (−)-Epigallocatechin-3-Gallate: Partners in Fighting Cancer

Zhang, L., He, Y., Wu, X., Zhao, G., Zhang, K., Yang, C. S., Reiter, R. J., & Zhang, J. (2019) · Cells · doi:10.3390/cells8070745 · Cited by 30

Maintenance therapy for B-chronic lymphocytic leukemia.

O'Brien, S. M., & Kay, N. E. (2011) · PubMed · Cited by 30

Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia

Liu, J., Masurekar, A. N., Johnson, S. M., Chakraborty, S., Griffiths, J., Smith, D. L., Alexander, S., Dempsey, C. E., Parker, C. A., Harrison, S., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.5528 · Cited by 30

Engineered Polymeric Micelles for Combinational Oxidation Anticancer Therapy through Concurrent HO-1 Inhibition and ROS Generation

Noh, J., Jung, E., Lee, J., Hyun, H., Hong, S., & Lee, D. (2019) · Biomacromolecules · doi:10.1021/acs.biomac.8b01802 · Cited by 30

Design and synthesis of isothiocyanate‐containing hybrid androgen receptor (AR) antagonist to downregulate AR and induce ferroptosis in GSH–Deficient prostate cancer cells

Qin, Z., Ou, S., Xu, L., Sorensen, K., Zhang, Y., Hu, D., Yang, Z., Hu, W., Chen, F., & Prins, G. S. (2021) · Chemical Biology & Drug Design · doi:10.1111/cbdd.13826 · Cited by 32

Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: Thiol reactivity and its implications

Crampsie, M. A., Pandey, M. K., Desai, D. H., Spallholz, J. E., Amin, S., & Sharma, A. K. (2012) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2012.08.022 · Cited by 30

Menadione Reduction by Pharmacological Doses of Ascorbate Induces an Oxidative Stress That Kills Breast Cancer Cells

Beck, R., Verrax, J., Dejeans, N., Taper, H. S., & Calderón, P. B. (2009) · International Journal of Toxicology · doi:10.1177/1091581809333139 · Cited by 30

Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical

Kumari, V., Dyba, M., Holland, R. J., Liang, Y., Singh, S. V., & Ji, X. (2016) · PLoS ONE · doi:10.1371/journal.pone.0163821 · Cited by 30

Quinoline based mono- and bis-(thio)carbohydrazones: synthesis, anticancer activity in 2D and 3D cancer and cancer stem cell models

Božić, A., Marinković, А., Bjelogrlić, S., Todorović, T. R., Cvijetić, I., Novaković, I., Muller, C. D., & Filipović, N. R. (2016) · RSC Advances · doi:10.1039/c6ra23940d · Cited by 30

Effects of Mammalian Thioredoxin Reductase Inhibitors

Arnér, E. S. J. (2020) · Handbook of experimental pharmacology · doi:10.1007/164_2020_393 · Cited by 30

Mobilization of Nuclear Copper by Green Tea Polyphenol Epicatechin-3-Gallate and Subsequent Prooxidant Breakage of Cellular DNA: Implications for Cancer Chemotherapy

Farhan, M., Oves, M., Chibber, S., Hadi, S. M., & Ahmad, A. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms18010034 · Cited by 29

Metabolic targets of watercress and PEITC in MCF-7 and MCF-10A cells explain differential sensitisation responses to ionising radiation

Giallourou, N., Rowland, I. R., Rothwell, S. D., Packham, G., Commane, D. M., & Swann, J. R. (2018) · European Journal of Nutrition · doi:10.1007/s00394-018-1789-8 · Cited by 29

Correspondence

Vereecque, R., Buffenoir, G., Gonzalez, R., Preudhomme, C., Fenaux, P., & Quesnel, B. (1999) · Leukemia Research · doi:10.1016/s0145-2126(98)00180-5 · Cited by 15

Selective killing of oncogenic transformed cells through ROS-mediated mechanism by β-phenylethyl isothiocyanates

Trachootham, D., Zhou, Y. N., Pelicano, H., Chiao, P. J., Liu, J., & Huang, P. (2006) · Cancer Research · Cited by 2

Targeting ROS: Selective killing of cancer cells by a cruciferous vegetable derived pro-oxidant compound

Wu, X., & Hua, X. (2007) · Cancer Biology & Therapy · doi:10.4161/cbt.6.5.4092 · Cited by 68

Selective elimination of cancer cells by PEITC: Biological basis and therapeutic implications

Trachootham, D. (2008) · Digital Commons-TMC (Texas Medical Center) · Cited by 1

Abstract 2645: PEITC induces cell death in melanoma cells through redox mechanisms

Ahmed, K. B. R., Li, F., & Huang, P. (2011) · Cancer Research · doi:10.1158/1538-7445.am2011-2645