Ten Genes for Inherited Breast Cancer

Biallelic Inactivation of BRCA2 in Fanconi Anemia

Howlett, N. G., Taniguchi, T., Olson, S., Cox, B., Waisfisz, Q., de Die-Smulders, C., Persky, N., Grompe, M., Joenje, H., Pals, G., et al. (2002) · Science · doi:10.1126/science.1073834 · Cited by 1,149

Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations

The CHEK2-Breast Cancer Consortium (2002) · Nature Genetics · doi:10.1038/ng879 · Cited by 1,104

PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

Rahman, N., Seal, S., Thompson, D. J., Kelly, P. F., Renwick, A., Elliott, A., Reid, S., Spanova, K., Barfoot, R., Chagtai, T., et al. (2006) · Nature Genetics · doi:10.1038/ng1959 · Cited by 1,026

Essential role for nuclear PTEN in maintaining chromosomal integrity

Shen, W. H., Balajee, A. S., Wang, J., Wu, H., Eng, C., Pandolfi, P. P., & Yin, Y. (2007) · Cell · doi:10.1016/j.cell.2006.11.042 · Cited by 979

Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2

Xia, B., Sheng, Q., Nakanishi, K., Ohashi, A., Wu, J., Christ, N., Liu, X., Jasin, M., Couch, F. J., & Livingston, D. M. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.05.022 · Cited by 861

ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles

Renwick, A., Thompson, D. J., Seal, S., Kelly, P. F., Chagtai, T., Ahmed, M., North, B. V., Jayatilake, H., Barfoot, R., Spanova, K., et al. (2006) · Nature Genetics · doi:10.1038/ng1837 · Cited by 770

Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles

The Breast Cancer Susceptibility Collaboration (UK), Seal, S., Thompson, D., Renwick, A., Elliott, A., Kelly, P., Barfoot, R., Chagtai, T., Jayatilake, H., Ahmed, M., et al. (2006) · Nature Genetics · doi:10.1038/ng1902 · Cited by 746

Spectrum of Mutations in BRCA1, BRCA2, CHEK2, and TP53 in Families at High Risk of Breast Cancer

Walsh, T., Casadei, S., Coats, K. H., Swisher, E. M., Stray, S. M., Higgins, J., Roach, K. C., Mandell, J. B., Lee, M. K., Čierniková, S., et al. (2006) · JAMA · doi:10.1001/jama.295.12.1379 · Cited by 673

Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

Reid, S., Schindler, D., Hanenberg, H., Barker, K., Hanks, S., Kalb, R., Neveling, K., Kelly, P., Seal, S., Freund, M., et al. (2007) · Nature Genetics · doi:10.1038/ng1947 · Cited by 642

A recurrent mutation in PALB2 in Finnish cancer families

Erkko, H., Xia, B., Nikkilä, J., Schleutker, J., Syrjäkoski, K., Mannermaa, A., Kallioniemi, A. H., Pylkäs, K., Karppinen, S., Rapakko, K., et al. (2007) · Nature · doi:10.1038/nature05609 · Cited by 471

Germline RAP80 mutations and susceptibility to breast cancer

Akbari, M. R., Ghadirian, P., Robidoux, A., Foumani, M. G., Sun, Y., Royer, R., Zandvakili, I., Lynch, H. T., & Narod, S. A. (2008) · Breast Cancer Research and Treatment · doi:10.1007/s10549-008-9938-z · Cited by 23

Breast cancer histologic subtypes show excess familial clustering

Henry, N. L., & Cannon‐Albright, L. (2019) · Cancer · doi:10.1002/cncr.32198 · Cited by 22

RAD50 and NBS1 are not likely to be susceptibility genes in Chinese non-BRCA1/2 hereditary breast cancer

He, M. Y., Di, G., Cao, A., Hu, Z., Jin, W., Shen, Z., & Shao, Z. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1700-2 · Cited by 22

Association of PALB2 sequence variants with the risk of familial and early-onset breast cancer in a South-American population

Leyton, Y., González‐Hormazábal, P., Blanco, R., Bravo, T., Fernández‐Ramires, R., Morales, S., Landeros, N., Reyes, J. M., Peralta, O., Tapia, J. C., et al. (2015) · BMC Cancer · doi:10.1186/s12885-015-1033-3 · Cited by 22

Alterations in replication timing of cancer‐related genes in malignant human breast cancer cells

Fritz, A. J., Sinha, S., Marella, N. V., & Berezney, R. (2012) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24447 · Cited by 24

XRCC1 and OGG1 Gene Polymorphisms and Breast Cancer: A Systematic Review of Literature.

Moghaddam, A. S., Nazarzadeh, M., Noroozi, R., Darvish, H., & Jarrahi, A. M. (2016) · PubMed Central · doi:10.17795/ijcp-3467 · Cited by 22

Integrated analysis of promoter methylation and expression of telomere related genes in breast cancer

Heng, J., Zhang, F., Guo, X., Tang, L., Peng, L., Luo, X., Xu, X., Wang, S., Dai, L., & Wang, J. (2017) · Oncotarget · doi:10.18632/oncotarget.16036 · Cited by 22

Nanoparticles for tumor targeting

Jiang, T., Jin, K., Liu, X., & Pang, Z. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-101914-6.00008-9 · Cited by 22

miRNA 196a2(rs11614913) & 146a(rs2910164) Polymorphisms & Breast Cancer Risk for Women in an Iranian Population

Nejati-Azar, A., & Alivand, M. R. (2018) · Personalized Medicine · doi:10.2217/pme-2017-0088 · Cited by 22

E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells

Duan, H., Mansour, S., Reed, R., Gillis, M. K., Parent, B., Liu, B., Sztupinszki, Z. M., Birkbak, N. J., Szállási, Z., Elia, A. E. H., et al. (2020) · The Journal of Cell Biology · doi:10.1083/jcb.201908192 · Cited by 22

Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cyclePreprint

Dimitrov, S. D., Lu, D., Naetar, N., Hu, Y., Pathania, S., Kanellopoulou, C., & Livingston, D. M. (2013) · Genes & Development · doi:10.1101/gad.225045.113 · Cited by 22

ATM germline mutations in Spanish early‐onset breast cancer patients negative for BRCA1/BRCA2 mutations

Brunet, J., Gutiérrez‐Enríquez, S., Torres, A., Bérez, V, Sanjosé, S., Galceran, J., Izquierdo, À., Menéndez, J., Gumà, J., & Borràs, J. (2008) · Clinical Genetics · doi:10.1111/j.1399-0004.2008.00987.x · Cited by 21

Targeted core-shell nanoparticles for precise CTCF gene insert in treatment of metastatic breast cancer

Duan, J., Bao, C., Xie, Y., Guo, H., Liu, Y., Li, J., Liu, R., Li, P., Bai, J., Yan, Y., et al. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.10.007 · Cited by 21

Breast Cancer in a RAD51D Mutation Carrier: Case Report and Review of the Literature

Baker, J. L., Schwab, R. B., Wallace, A. M., & Madlensky, L. (2014) · Clinical Breast Cancer · doi:10.1016/j.clbc.2014.08.005 · Cited by 21

Targeting Homologous Recombination Repair in Cancer

Willers, H., Pfäffle, H. N., & Zou, L. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-384999-1.10007-1 · Cited by 21

The Spindle-Assembly Checkpoint, Aneuploidy, and Gastrointestinal Cancer

Scully, R. (2010) · New England Journal of Medicine · doi:10.1056/nejme1008017 · Cited by 21

FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells

Kitao, H., Nanda, I., Sugino, R. P., Kinomura, A., Yamazoe, M., Arakawa, H., Schmid, M., Innan, H., Hiom, K. J., & Takata, M. (2011) · Genes to Cells · doi:10.1111/j.1365-2443.2011.01523.x · Cited by 20

Genetic polymorphisms in RAD23B and XPC modulate DNA repair capacity and breast cancer risk in Puerto Rican women

Pérez‐Mayoral, J., Pacheco‐Torres, A. L., Morales, L., Acosta, H., Matta, J. L., & Dutil, J. (2013) · Molecular Carcinogenesis · doi:10.1002/mc.22056 · Cited by 20

Deletion of Chromosomes 13q and 14q Is a Common Feature of Tumors with BRCA2 Mutations

Rouault, A., Banneau, G., MacGrogan, G. M., Jones, N. B., Elarouci, N., Barouk-Simonet, E., Venat, L., Coupier, I., Letouzé, É., de Reyniès, A., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052079 · Cited by 20

To the Rescue: The Fanconi Anemia Genome Stability Pathway Salvages Replication Forks

Moldovan, G., & D’Andrea, A. D. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.06.006 · Cited by 22

Absence of CHEK2*1100delC mutation in families with hereditary breast cancer in North America

Iniesta, M. D., Gorin, M. A., Chien, L.-C., Thomas, S. M., Milliron, K. J., Douglas, J. A., & Merajver, S. D. (2010) · Cancer Genetics and Cytogenetics · doi:10.1016/j.cancergencyto.2010.07.124 · Cited by 21

Differential expression of DNA repair genes in Hispanic women with breast cancer.

Matta, J. L., Morales, L., Dutil, J., Bayona, M., Álvarez, C., & Suarez, E. L. (2013) · PubMed · doi:10.9777/mcb.2013.10006 · Cited by 20

Promotion of BRCA1-associated triple-negative breast cancer by ovarian hormones

Lee, E. Y.-H. P. (2008) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e3282f42237 · Cited by 20

Mutational analysis of telomere genes in BRCA1/2-negative breast cancer families with very short telomeres

Yanowsky, K., Barroso, A., Osório, A., Urioste, M., Benitez, J. J., & Martínez–Delgado, B. (2012) · Breast Cancer Research and Treatment · doi:10.1007/s10549-012-2141-2 · Cited by 19

Germline variants in cancer genes in high-risk non-BRCA patients from Puerto Rico

Dutil, J., Teer, J. K., Golubeva, V. A., Yoder, S., Tong, W. L., Arroyo, N., Karam, R., Echenique, M. M., Matta, J. L., & Monteiro, Á. N. A. (2019) · Scientific Reports · doi:10.1038/s41598-019-54170-6 · Cited by 19

Formal modeling and analysis of the hexosamine biosynthetic pathway: role of O-linked N-acetylglucosamine transferase in oncogenesis and cancer progression

Saeed, T., Ahmad, J., Kanwal, S., Holowatyj, A. N., Sheikh, I. A., Paracha, R. Z., Shafi, A., Siddiqa, A., Bibi, Z., Khan, M., et al. (2016) · PeerJ · doi:10.7717/peerj.2348 · Cited by 19

The Fanconi anemia pathway: Insights from somatic cell genetics using DT40 cell line

Takata, M., Ishiai, M., & Kitao, H. (2009) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2008.12.012 · Cited by 18

Associations of Two Common Genetic Variants with Breast Cancer Risk in a Chinese Population: A Stratified Interaction Analysis

Lin, Y., Fu, F., Chen, M., Huang, M., & Wang, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0115707 · Cited by 18

Identification of germline alterations of the mad homology 2 domain of SMAD3 and SMAD4 from the Ontario site of the breast cancer family registry (CFR)

Tram, E., Ibrahim-zada, I., Briollais, L., Knight, J. A., Andrulis, I. L., & Özçelik, H. (2011) · Breast Cancer Research · doi:10.1186/bcr2926 · Cited by 18

Breast Cancer Stem Cells and Tumor Suppressor Genes

Hwang‐Verslues, W. W., Chang, K., Lee, E. Y.-H. P., & Lee, W. (2008) · Journal of the Formosan Medical Association · doi:10.1016/s0929-6646(08)60188-6 · Cited by 18

Identification of women with an increased risk of developing radiation-induced breast cancer

Cardis, E., Hall, J. A., & Tavtigian, S. V. (2007) · Breast Cancer Research · doi:10.1186/bcr1733 · Cited by 18

Joint Analysis of Multiple Traits in Rare Variant Association Studies

Wang, Z., Wang, X., Sha, Q., & Zhang, S. (2016) · Annals of Human Genetics · doi:10.1111/ahg.12149 · Cited by 17

A non-BRCA1/2 hereditary breast cancer sub-group defined by aCGH profiling of genetically related patients

Didraga, M., van Beers, E. H., Joosse, S. A., Brandwijk, K. I. M., Oldenburg, R. A., Wessels, L. F. A., Hogervorst, F. B. L., Ligtenberg, M. J. L., Hoogerbrugge, N., Verhoef, S., et al. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1357-x · Cited by 19

Do Single Nucleotide Polymorphisms in Xenobiotic Metabolizing Genes Determine Breast Cancer Susceptibility and Treatment Outcomes?

Singh, V. K., Parmar, D., & Singh, M. P. (2008) · Cancer Investigation · doi:10.1080/07357900801953196 · Cited by 17

Transcriptome sequencing profiles reveal lncRNAs may involve in breast cancer (ER/PR positive type) by interaction with RAS associated genes

Jia, Y., Shi, L., Yun, F., Liu, X., Chen, Y., Wang, M., Chen, C., Ren, Y., Bao, Y., & Wang, L. (2019) · Pathology - Research and Practice · doi:10.1016/j.prp.2019.03.033 · Cited by 17

Tumor hypoxia and genetic alterations in sporadic cancers

Koi, M., & Boland, C. R. (2011) · Journal of obstetrics and gynaecology research · doi:10.1111/j.1447-0756.2010.01377.x · Cited by 17

Haplotype analysis of eight genes of the monoubiquitinated FANCD2–DNA damage–repair pathway in breast cancer patients

Tang, L., Chen, F., Wang, H., Hu, X.-L., Dai, X., Mao, J., Zheng-tang, S., Wu, Y., Wang, S.-M., Hai, J., et al. (2013) · Cancer Epidemiology · doi:10.1016/j.canep.2012.12.010 · Cited by 17

CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases

Apostolou, P., Fostira, F., Papamentzelopoulou, M., Michelli, M., Panopoulos, C., Fountzilas, G., Konstantopoulou, I., Voutsinas, G. E., & Yannoukakos, D. (2015) · Cancer Genetics · doi:10.1016/j.cancergen.2015.02.006 · Cited by 16

A novel method to test associations between a weighted combination of phenotypes and genetic variants

Zhu, H., Zhang, S., & Sha, Q. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190788 · Cited by 16

The association of CASC16 variants with breast Cancer risk in a northwest Chinese female population

Zuo, X., Wang, H., Mi, Y., Zhang, Y., Wang, X., Yang, Y. P., & Zhai, S. (2020) · Molecular Medicine · doi:10.1186/s10020-020-0137-7 · Cited by 16

Low prevalence of CDKN2A/ARF mutations among early-onset cancers of breast, pancreas and malignant melanoma in Poland

Dębniak, T., van de Wetering, T., Scott, R. J., Nagay, L., Cybulski, C., Górski, B., Jakubowska, A., Gronwald, J., Masojć, B., Huzarski, T., et al. (2008) · European Journal of Cancer Prevention · doi:10.1097/cej.0b013e3282f75eb1 · Cited by 16

Pioneering geneticist Mary-Claire King receives the 2014 Lasker~Koshland Special Achievement Award in Medical Science

Hurst, J. H. (2014) · Journal of Clinical Investigation · doi:10.1172/jci78507 · Cited by 16

Dual inactivation of Hus1 and p53 in the mouse mammary gland results in accumulation of damaged cells and impaired tissue regeneration

Yazinski, S. A., Westcott, P. M. K., Ong, K., Pinkas, J., Peters, R. M., & Weiss, R. S. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904965106 · Cited by 16

What is wrong with Fanconi anemia cells?

Cantor, S. B., & Brosh, R. M. (2014) · Cell Cycle · doi:10.4161/15384101.2014.980633 · Cited by 16

Breast cancer genetic susceptibility: With focus in Saudi Arabia

Alshammari, F. D. (2019) · Journal of Oncological Sciences · doi:10.1016/j.jons.2019.02.001 · Cited by 16

Complicated Supercomplexes

Livingston, D. M. (2009) · Science · doi:10.1126/science.1174839 · Cited by 16

Identification of Novel Circular RNAs of the Human Protein Arginine Methyltransferase 1 (PRMT1) Gene, Expressed in Breast Cancer Cells

Papatsirou, M., Diamantopoulos, M. A., Katsaraki, K., Kletsas, D., Kontos, C. K., & Scorilas, A. (2022) · Genes · doi:10.3390/genes13071133 · Cited by 15

Contribution of RAD51D germline mutations in breast and ovarian cancer in Greece

Konstanta, I., Fostira, F., Apostolou, P., Stratikos, E., Kalfakakou, D., Παμπάνος, Α., Κollia, P., PAPADIMITRIOU, C. A., Konstantopoulou, I., & Yannoukakos, D. (2018) · Journal of Human Genetics · doi:10.1038/s10038-018-0498-8 · Cited by 15

CHEK2*1100delC does not contribute to risk to breast cancer among Malay, Chinese and Indians in Malaysia

Thirthagiri, E., Cheong, L. S., Yip, C. H., & Teo, S. (2009) · Familial Cancer · doi:10.1007/s10689-009-9244-x · Cited by 15

Haplotype of the C61G BRCA1 Mutation in Polish and Jewish Individuals

Kaufman, B., Laitman, Y., Gronwald, J., Lubiński, J., & Friedman, E. (2009) · Genetic Testing and Molecular Biomarkers · doi:10.1089/gtmb.2009.0001 · Cited by 15

In vitro model for DNA double‐strand break repair analysis in breast cancer reveals cell type–specific associations with age and prognosis

Deniz, M., Kaufmann, J., Stahl, A., Gundelach, T., Janni, W., Hoffmann, I., Keimling, M., Hampp, S., Ihle, M., & Wiesmüller, L. (2016) · The FASEB Journal · doi:10.1096/fj.201600453r · Cited by 15

The RNF146 and ECHDC1 genes as candidates for inherited breast and ovarian cancer in Jewish Ashkenazi women

Distelman-Menachem, T., Laitman, Y., Kaufman, B., & Friedman, E. (2009) · Familial Cancer · doi:10.1007/s10689-009-9255-7 · Cited by 15

Against Lung Cancer Cells: To Be, or Not to Be, That Is the Problem

Okumura, N., Yoshida, H., Kitagishi, Y., Nishimura, Y., Iseki, S., & Matsuda, S. (2012) · Lung Cancer International · doi:10.1155/2012/659365 · Cited by 15

Adaptive clustering and adaptive weighting methods to detect disease associated rare variants

Sha, Q., Wang, S., & Zhang, S. (2012) · European Journal of Human Genetics · doi:10.1038/ejhg.2012.143 · Cited by 16

Detection of New Point Mutations of BRCA1 and BRCA2 in Breast Cancer Patients

Bensam, M., Hafez, E. S. E., Awad, D., El-Saadani, M., & Balbaa, M. (2013) · Biochemical Genetics · doi:10.1007/s10528-013-9623-8 · Cited by 14

Association of ApaI and TaqI polymorphisms in VDR Gene with Breast Cancer

Matini, A. H., Jafarian-Dehkordi, N., Bahmani, B., Sharifi, M., Jahantigh, D., & Mazoochi, T. (2020) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2020.21.9.2667 · Cited by 14

Cancer of the Breast

Abeloff, M. D., Wolff, A. C., Weber, B. L., Zaks, T. Z., Sacchini, V., & McCormick, B. L. (2008) · Elsevier eBooks · doi:10.1016/b978-0-443-06694-8.50099-3 · Cited by 14

Regulation of the Nijmegen breakage syndrome 1 gene NBS1 by c-myc, p53 and coactivators mediates estrogen protection from DNA damage in breast cancer cells

WAN, R., Wu, J., Baloue, K., & Crowe, D. L. (2012) · International Journal of Oncology · doi:10.3892/ijo.2012.1757 · Cited by 14

Pathways Contributing to Development of Spontaneous Mammary Tumors in BALB/c-Trp53+/− Mice

Yan, H., Blackburn, A. C., McLary, S. C., Tao, L., Roberts, A. L., Xavier, E. A., Dickinson, E. S., Seo, J. H., Arenas, R. B., Otis, C. N., et al. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.090438 · Cited by 13

Identification and characterization of two novel germ line p53 mutations in the non-LFS/non-LFL breast cancer families in Chinese population

Cao, A., Jin, W., Shi, P.-C., Di, G., Shen, Z., & Shao, Z. (2009) · Breast Cancer Research and Treatment · doi:10.1007/s10549-009-0349-6 · Cited by 13

Locus heterogeneity disease genes encode proteins with high interconnectivity in the human protein interaction network

Keith, B. P., Robertson, D. L., & Hentges, K. E. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00434 · Cited by 13

FANCJ at the FORK

Cantor, S. B., & Nayak, S. U. (2016) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2016.02.003 · Cited by 13

Association of single nucleotide polymorphism rs3803662 with the risk of breast cancer

Yang, Y., Wang, W., Liu, G., Yu, Y., & Liao, M. (2016) · Scientific Reports · doi:10.1038/srep29008 · Cited by 13

The Influence of Common Polymorphisms on Breast Cancer

Eccles, D., & Tapper, W. (2010) · Cancer treatment and research · doi:10.1007/978-1-4419-6033-7_2 · Cited by 13

Molecular Oncology of Breast Cancer

Ioan, A.-M., Klobocista, M. M., Shirazi, S., & Press, M. F. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-5221-0.00028-0 · Cited by 13

Hereditary Cancer Syndromes

Fostira, F., Thodi, G., Konstantopoulou, I., Sandaltzopoulos, R., & Yannoukakos, D. (2023) · American Registry of PathologyArlington, Virginia eBooks · doi:10.55418/9781933477282-03 · Cited by 13

Will knowledge of human genome variation result in changing cancer paradigms?

Gottlieb, B., Beitel, L. K., & Trifiro, M. A. (2007) · BioEssays · doi:10.1002/bies.20595 · Cited by 13

Breast Cancer Susceptibility Genes

Apostolou, P., Vratimos, A., & Fostira, F. (2015) · Wiley eBooks · doi:10.1002/9780470015902.a0025847 · Cited by 13

Kernel-Machine Testing Coupled with a Rank-Truncation Method for Genetic Pathway Analysis

Yan, Q., Tiwari, H. K., Yi, N., Lin, W., Gao, G., Lou, X., Cui, X., & Liu, N. (2014) · Genetic Epidemiology · doi:10.1002/gepi.21813 · Cited by 13

CAG Repeat Variants in the POLG1 Gene Encoding mtDNA Polymerase-Gamma and Risk of Breast Cancer in African-American Women

Azrak, S., Vanniarajan, A., Zirpoli, G., Ambrosone, C. B., Bandera, E. V., Bovbjerg, D. H., Jandorf, L. H., Ciupak, G. L., Davis, W., Pawlish, K. S., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029548 · Cited by 12

Surgical Management of Inherited Breast Cancer: Role of Breast-Conserving Surgery

Magnoni, F., Sacchini, V., Veronesi, P., Bianchi, B., Bottazzoli, E. I., Tagliaferri, V., Mazzotta, E., Castelnovo, G., Deguidi, G., Rossi, E. M. C., et al. (2022) · Cancers · doi:10.3390/cancers14133245 · Cited by 12

Five common single nucleotide polymorphisms in the PALB2 gene and susceptibility to breast cancer in eastern Chinese population

Cao, A., Yu, K., Yin, W., Jin, W., Di, G., Shen, Z., & Shao, Z. (2009) · Breast Cancer Research and Treatment · doi:10.1007/s10549-009-0637-1 · Cited by 12

Testing an optimally weighted combination of common and/or rare variants with multiple traits

Wang, Z., Sha, Q., Fang, S., Zhang, K., & Zhang, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0201186 · Cited by 12

Enhancement of the RAD51 Recombinase Activity by the Tumor Suppressor PALB2

Dray, E. V., Etchin, J., Wiese, C., Saro, D., Williams, G. J., Hammel, M., Yu, X., Galkin, V. E., Liu, D., Tsai, M.-S., et al. (2010) · doi:10.2172/993859 · Cited by 12

Collaboration of Colorado Cancer Genetic Counselors to Integrate Next Generation Sequencing Panels into Clinical Practice

Schneider, K. W., Anguiano, A., Axell, L., Barth, C., Crow, K., Gilstrap, M., Hamlington, B., Lesh, S., Mullineaux, L. G., Rahm, A. K., et al. (2014) · Journal of Genetic Counseling · doi:10.1007/s10897-014-9718-3 · Cited by 11

Saliva samples as a source of DNA for high throughput genotyping: an acceptable and sufficient means in improvement of risk estimation throughout mammographic diagnostics

Pöhls, U. G., Hack, C. C., Ekici, A. B., Beckmann, M. W., Fasching, P. A., Ruebner, M., & Huebner, H. (2018) · European journal of medical research · doi:10.1186/s40001-018-0318-9 · Cited by 11

From seeds to survival rates: investigating Linum usitatissimum’s potential against ovarian cancer through network pharmacology

Islam, M. M., Sreeharsha, N., Alshabrmi, F. M., Asif, A. H., Al‐Dhubiab, B. E., Anwer, M. K., Krishnasamy, R., & Rehman, A. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1285258 · Cited by 11

XRCC1 gene polymorphisms in a population sample and in women with a family history of breast cancer from Rio de Janeiro (Brazil)

Falagan-Lotsch, P., Rodrigues, M. S., Esteves, V. F., Vieira, R. J. D. S., Amendola, L. C., Pagnoncelli, D., da Paixão, J. C., & Gallo, C. V. D. M. (2009) · Genetics and Molecular Biology · doi:10.1590/s1415-47572009000200008 · Cited by 11

Estrogen promotes increased breast cancer cell proliferation and migration through downregulation of CPEB1 expression

Sovijit, W., Watcharin, S., Ishii, Y., Kambe, J., Fujita, T., Watanabe, G., Yamaguchi, H., & Nagaoka, K. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.10.085 · Cited by 12

Unlocking the Molecular Mechanisms of DNA Repair and Platinum Drug Resistance in Cancer Chemotherapy

Yu, J. (2009) · Current Drug Therapy · doi:10.2174/157488509787081895 · Cited by 11

Haplotypes of the I157T CHEK2 germline mutation in ethnically diverse populations

Kaufman, B., Laitman, Y., Gronwald, J., Winqvist, R., Irmejs, A., Lubiński, J., Pylkäs, K., Gardovskis, J., Miklaševičs, E., & Friedman, E. (2009) · Familial Cancer · doi:10.1007/s10689-009-9269-1 · Cited by 12

The role of BACH1 , BARD1 and TOPBP1 genes in familial breast cancer

Karppinen, S. (2009) · Cited by 11

A novel approach for haplotype-based association analysis using family data

Chen, Y., Li, X., & Li, J. (2010) · BMC Bioinformatics · doi:10.1186/1471-2105-11-s1-s45 · Cited by 10

Association detection between ordinal trait and rare variants based on adaptive combination of P values

Wang, M., Ma, W., & Zhou, Y. (2017) · Journal of Human Genetics · doi:10.1038/s10038-017-0354-2 · Cited by 10

Association Between Single-Nucleotide Polymorphisms in Breast Cancer Susceptibility Genes and Clinicopathological Characteristics

Wang, S., Zhang, K., Tang, L., Yang, Y., Wang, H., Zhou, Z., Pang, J., & Chen, F. (2021) · Clinical Epidemiology · doi:10.2147/clep.s292429 · Cited by 10

Interaction of p53 with BRC analogs: A comparative design assisted by ZDOCK and CABS-Dock simulation

Yuan, L., Liu, G., Zhao, D., Zhu, H., Qi, J., & Lü, K. (2022) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2022.134109 · Cited by 10

Genetic contribution of GADD45A to susceptibility to sporadic and non-BRCA1/2 familial breast cancers: a systematic evaluation in Chinese populations

Yu, K., Di, G., Li, W., Rao, N.-Y., Fan, L., Yuan, W. T., Hu, Z., Wu, J., Shen, Z., Huang, W., et al. (2009) · Breast Cancer Research and Treatment · doi:10.1007/s10549-009-0516-9 · Cited by 10

Mutation screening of breast cancer susceptibility genes in Chinese high-risk families: the results will develop the genetic testing strategy in China

Cao, A., Hu, Z., & Shao, Z. (2009) · Breast Cancer Research and Treatment · doi:10.1007/s10549-009-0598-4 · Cited by 10

A Rare Variant Association Test Based on Combinations of Single-Variant Tests

Sha, Q., & Zhang, S. (2014) · Genetic Epidemiology · doi:10.1002/gepi.21834 · Cited by 9

Long-term risk of second malignancies in women after breast conservation therapy for ductal carcinoma in situ or early-stage breast cancer

Kushner, C. J., Hwang, W., Wang, S., Solin, L. J., & Vapiwala, N. (2018) · Breast Cancer Research and Treatment · doi:10.1007/s10549-018-4729-7 · Cited by 9

Identification of Novel Susceptibility Genes for Breast Cancer – Genome-Wide Association Studies or Evaluation of Candidate Genes?

Meindl, A. (2009) · Breast Care · doi:10.1159/000211991 · Cited by 9

Association of Single-Nucleotide Polymorphisms in Monoubiquitinated FANCD2-DNA Damage Repair Pathway Genes With Breast Cancer in the Chinese Population

Chen, F., Wang, H., Li, H., Hu, X., Dai, X., Wang, S.-M., Yan, G.-J., Jiang, P., Hu, Y., Huang, J., et al. (2018) · Technology in Cancer Research & Treatment · doi:10.1177/1533033818819841 · Cited by 9

Breast Cancer Association Studies in a Han Chinese Population using 10 European-ancestry-associated Breast Cancer Susceptibility SNPs

Guan, Y., Yang, X., Yao, G., Qiu, F., Chen, J., Chen, L.-J., Ye, C.-S., & Li, M. (2014) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2014.15.1.85 · Cited by 9

TOPBP1 , CLSPN and PALB2 genes in familial breast cancer susceptibility

Erkko, H. (2008) · Cited by 9

Detecting association of rare and common variants based on cross-validation prediction error

Yang, X., Wang, S., Zhang, S., & Sha, Q. (2017) · Genetic Epidemiology · doi:10.1002/gepi.22034 · Cited by 8

Involvement of ERCC1 (rs3212986) and ERCC2 (rs1799793, rs13181) polymorphisms of DNA repair genes in breast cancer occurrence in Burkina Faso

Adico, M. D. W., Zouré, A. A., Sombié, H. K., Kiendrebeogo, I. T., Dabré, S., Amegnona, L. J., Bakyono, B. S., Traoré, L., Ouedraogo, T. C., Ouédraogo, R. A., et al. (2023) · Molecular Genetics & Genomic Medicine · doi:10.1002/mgg3.2134 · Cited by 8

Results of a population-based screening for hereditary breast cancer in a region of North-Central Italy: contribution of BRCA1/2 germ-line mutations

Seymour, I. J., Casadei, S., Zampiga, V., Rosato, S., Danesi, R., Scarpi, E., Falcini, F., Strada, M., Morini, N., Naldoni, C., et al. (2007) · Breast Cancer Research and Treatment · doi:10.1007/s10549-007-9846-7 · Cited by 8

Cytogenetic and molecular diagnosis of Fanconi anemia revealed two hidden phenotypes: Disorder of sex development and cerebro‐oculo‐facio‐skeletal syndrome

Ali, A. B. H., Amouri, A., Sayeb, M., Makni, S. K., Hammami, W., Naouali, C., Dallali, H., Romdhane, L., Bashamboo, A., McElreavey, K., et al. (2019) · Molecular Genetics & Genomic Medicine · doi:10.1002/mgg3.694 · Cited by 8

A de novo frameshift mutation in ZEB2 causes polledness, abnormal skull shape, small body stature and subfertility in Fleckvieh cattle

Gehrke, L. J., Upadhyay, M. R., Heidrich, K., Kunz, E., Klaus-Halla, D., Weber, F., Zerbe, H., Seichter, D., Graf, A., Krebs, S., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-73807-5 · Cited by 8

The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulatingNTN4expression

Yang, H. K., Ting, X., Geng, Y., Xie, Y., Nierenberg, J. L., Huo, Y., Zhou, Y., Huang, Y., Yu, Y., Yu, X.-Y., et al. (2022) · Science Advances · doi:10.1126/sciadv.abn3509 · Cited by 8

Inherited breast and ovarian cancer

Szabo, C., & King, M. (1995) · Human Molecular Genetics · doi:10.1093/hmg/4.suppl_1.1811 · Cited by 202

The Fanconi anaemia/BRCA pathway and cancer susceptibility. Searching for new therapeutic targets

García, M. J., & Benitez, J. J. (2008) · Clinical & Translational Oncology · doi:10.1007/s12094-008-0160-6 · Cited by 34

Tumor suppressor genes and breast cancer

Buchholz, T. A., Weil, M. M., Story, M. D., Strom, E. A., Brock, W. A., & McNeese, M. D. (1999) · Radiation Oncology Investigations · doi:10.1002/(sici)1520-6823(1999)7:2 · Cited by 32

Breast Cancer Predisposition Syndromes

Hemel, D., & Domchek, S. M. (2010) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2010.06.004 · Cited by 30

Breast Cancer Gene (BRCA1, BRCA2)

Lee, C. H. (2003) · Journal of Medicine and Life Science · doi:10.22730/jmls.2003.1.1.1