FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

Pei, Huadong, Li, Liang, Fridley, Brooke L., Jenkins, Gregory D., Kalari, Krishna R., Lingle, Wilma, Petersen, Gloria, Lou, Zhenkun, Wang, Liewei·2009·Cancer Cell

DOI 10.1016/j.ccr.2009.07.016

Cited by (727)

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Suhua Xia, Zhenyu Feng, Xiaowei Qi, Yuan Yin, Jianqiang Jin, Yufeng Wu, Hao-Rong Wu, Yizhong Feng, Min Tao · 2014 · Medical Oncology
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Xudong Huang, Jian Zheng, Jun Li, Xu Che, Wenle Tan, Wen Tan, Mingming Shao, Xinxin Cheng, Zhongli Du, Yanjie Zhao et al. · 2018 · Theranostics
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Yun Feng, Hongliang Liu, Bensong Duan, Zhensheng Liu, James L. Abbruzzese, Kyle M. Walsh, Xuefeng Zhang, Qingyi Wei · 2019 · Carcinogenesis
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Jie Yan, Liangcai Wu, Congwei Jia, Shuangni Yu, Zhaohui Lu, Yueping Sun, Jie Chen · 2020 · Aging
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IFNs, ISGylation and cancer: Cui prodest?
Andrea Sgorbissa, Claudio Brancolini · 2012 · Cytokine & Growth Factor Reviews
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Melanie Gérard, Angélique Deleersnijder, Jonas Demeulemeester, Zeger Debyser, Veerle Baekelandt · 2011 · Molecular Neurobiology
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Ke Zhang, Panling Xu, Yujie Li, Shu Dong, Huifeng Gao, Lianyu Chen, Hao Chen, Zhen Chen · 2022 · BMC Genomic Data
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Liang Li, Brooke L. Fridley, Krishna R. Kalari, Nifang Niu, Gregory D. Jenkins, Anthony J. Batzler, Ryan Abo, Daniel J. Schaid, Liewei Wang · 2014 · BMC Genomics
Assembly of the FKBP51–PHLPP2–AKT signaling complex in cerebral ischemia/reperfusion injury in rats
Xiue Wei, Feng-Yu Zhang, Kai Wang, Qingxiu C. Zhang, Liangqun Rong · 2014 · Brain Research
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William Adrian Hall, Aleksandra V. Petrova, Lauren Elizabeth Colbert, Claire W. Hardy, Sarah B. Fisher, Burcu Saka, Joseph W. Shelton, Matthew D. Warren, Brooke G. Pantazides, K. Gandhi et al. · 2013 · Oncogene
Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer
Giuseppina Sannino, Nicole S. Armbruster, Mona Bodenhöfer, Ursula Haerle, Diana Behrens, Malte Buchholz, Ulrich Rothbauer, Bence Sipos, Christian Schmees · 2016 · Oncotarget
Overexpressed gene signature of EPH receptor A/B family in cancer patients-comprehensive analyses from the public high-throughput database.
Nam Nhut Phan, Shirui Liu, Chih‐Yang Wang, Hui‐Ping Hsu, Ming‐Derg Lai, Chung-Yen Li, Chien‐Fu Chen, Chung-Chieh Chiao, Meng‐Chi Yen, Zhengda Sun et al. · 2020 · PubMed Central
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Sisi Qin, James N. Ingle, Mohan Liu, Jia Yu, Donald Lawrence Wickerham, Michiaki Kubo, Richard M. Weinshilboum, Liewei Wang · 2017 · Breast Cancer Research
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