FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

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Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas

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Budding Uninhibited by Benzimidazole 1 in pancreatic cancer: theoretical, mechanistic and bioinformatic insights

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Inhibition of FKBP5 alleviates obstetric antiphospholipid syndrome by regulating macrophage polarization

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Embracing change: Chemical modifications of nucleic acid bases as epigenetic marks

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Role of FK506 binding protein 51 in central nervous system diseases

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Impaired insulin secretion via the Wnt5a/β-catenin pathway contributes to diabetes development in pancreatic cancer

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Statin use and outcomes in advanced prostate cancer:Secondary analysis of the SPARTAN trial

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T cells engineered against Dickkopf-1-A2 complex can be used to treat HLA-A2+ solid and hematologic cancers

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Identifying significant genes as prognostic biomarkers in pancreatic cancer through integrated transcriptomic and in silico pharmacology approaches

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Chronic military stress and glandular epithelial tumor biology: an integrative neuroendocrine–inflammatory framework with insights from microgravity gene discovery

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Targeting DGAT1 reprograms lipid landscape and restores CD8⁺ T cell immunity in pancreatic cancer

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PHLPP is neither a Phosphatase nor a Tumor Suppressor

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FKBP5 (FK506 binding protein 5)

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Posttranslational regulation of Akt in human

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Identification of therapeutic targets and prognostic biomarkers among CC chemokines in the pancreatic adenocarcinoma microenvironment

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Leucine rich repeat LGI family member 3: Integrative analyses support its prognostic association with pancreatic adenocarcinoma

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Integrative human pan-cancer analysis of NDC80

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Linking the immunophilin FKBP5 to taxol resistance in ovarian cancer

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Corticosteroid Receptors, Their Chaperones and Cochaperones: How Do They Modulate Adipogenesis?

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Comprehensive Dissection of Transcriptome Data and Regulatory Factors in Pancreatic Cancer Cells

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Chaperoning skin atrophy

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The therapeutic efficacy for targeting the PI3K signaling pathway for fighting breast, prostate and multiple myeloma cancer cells

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Functional Genomics Based on Germline Genome-Wide Association Studies of Endocrine Therapy for Breast Cancer

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Medical Therapy for Advanced Pancreatic Cancer: Work in Progress

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Understanding the function of the JunB transcription factor in anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma

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Functional metabolic phenotyping of human pancreatic ductal adenocarcinomaPreprint

Heid, I., Karakaya, S., Münch, C., Lueong, S., Winkelkotte, A. M., Liffers, S. T., Godfrey, L., Cheung, P. F., Savvatakis, K., Topping, G. J., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.23.452145 · Cited by 1

Comprehensive Analysis of the Transcriptional Expressions and Prognostic Value of S100A Family in Pancreatic Ductal AdenocarcinomaPreprint

Li, H., Wang, J., Jin, X., Жао, Л., Ye, H., Ma, Y., Jiang, X., & Yu, Z. (2021) · Research Square · doi:10.21203/rs.3.rs-149466/v1 · Cited by 1

Elimination of FKBP51 attenuates CCl4-induced liver injury via enhancement of mitochondrial function by increased Parkin activityPreprint

Qiu, B., Zhong, Z., Dou, L., Xu, Y., Zou, Y., Weldon, K. S., Wang, J., Zhang, L., Liu, M., Williams, K. E., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2679397/v1 · Cited by 1

Bone Morphogenetic Protein (BMP) signaling upregulates expression of ID1 and ID3 in pancreatitis and pancreatic ductal adenocarcinomaPreprint

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Biochemical analysis of human cancer-associated pseudokinases

Bailey, F. P. (2014) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)

Akt signaling and coordinated changes in the distribution and expression of akt-regulating phosphatases

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Regulation of PHLPP2 Expression in AML

Theede, K. M. (2012) · University of Minnesota Digital Conservancy (University of Minnesota)

Effects of immunosuppressive drugs on human adipose tissue metabolism

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Overexpression of Androgen Receptor in Prostate Cancer

Urbanucci, A. (2012) · Tampere University Institutional Repository (Tampere University)

The Co-chaperones FKBP51 and PP5 Control Nuclear Receptor Phosphorylation and Adipogenesis

Stechschulte, L. A. (2013) · OhioLink ETD Center (Ohio Library and Information Network)

Construction of pancreatic cancer double-factor regulatory network based on chip data on the transcriptional level

ZhaoTong, L.-L., & LiuNa, T.-F. (2014)

Regulation and Function of the Cancer Stem Cell Transcription Factors GLI1 and Kruppel-like Factor 4

Vanderbilt, D. B. (2015) · The Research Repository @ WVU (West Virginia University) · doi:10.33915/etd.6863

Investigating the feasibility of incorporating Vpx into lentiviral gene therapy vectors: at a global and targeted scale

McAllery, S. (2016) · The Sydney eScholarship Repository (The University of Sydney)

Characterising novel phosphatase enzymes important in regulating androgen receptor function in the progression of castrate resistant prostate cancer

Grey, J. (2017)

The critical role of cysteine import and metabolism in pancreatic cancer

Badgley, M. A. (2017) · doi:10.7916/d8db8dhx

Alterations in gene expression induced by oxaliplatin based chemotherapy in colorectal cancer

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Apoptosis-Inducing Factor Mediates Metabolism and Oxidative Stress Signaling through Functionally Uncoupled Mechanisms to the Benefit of Tumorigenesis

Scott, A. J. (2019) · NDSU Repository (North Dakota State University)

Gene Ranking: A Novel Approach Using Multi-Objective Genetic Algorithm

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Identification and Characterization of Two Potential Novel Regulators of Apoptosis, MAGE-D2 and SUMI-1

Clegg, H. V. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/dcpq-a148

FATE1: Contributor to Tumor Cell Fitness and Example of an Oncogene-Activated Cancer Testis Antigen

Taus, P. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/6ww8-8048

Molecular Profiling in Pancreatic Ductal Adenocarcinoma

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HSP90-Based Heterocomplex as Essential Regulator for Cancer Disease

Galigniana, M. D. (2019) · Heat shock proteins · doi:10.1007/978-3-030-23158-3_2

Prognostic Biomarker Identification for Pancreatic Cancer by Analyzing Multiple mRNA Microarray and microRNA Expression Datasets

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Chemical Systems Biology Reveals Mechanisms of Glucocorticoid Receptor SignalingPreprint

Bruno, N. E., Nwachukwu, J. C., Srinivasan, S., Nettles, C. C., Izard, T., Jin, Z., Boregowda, S. V., Phinney, D. G., Elemento, O., Liu, X., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.15.153270

Peer Review #2 of "Identifying disease-associated signaling pathways through a novel effector gene analysis (v0.1)"

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Metabolic effects of oncogenic K-Ras in cancer cells

Bergner, R. (2018) · doi:10.25560/82596

Genome-wide regulation of glucocorticoid signaling by SUMO modifications

Paakinaho, V. (2014) · UEF eRepo (University of Eastern Finland)

KPNA4 Serves as A Biomarker For Pancreatic Adnenocarcinoma KPNA4 Serves as A Promising Diagnostic and Prognostic Biomarker For Human Pancreatic AdenocarcinomaPreprint

Zhou, Y., Zhu, H., Chu, Y., Luo, M., Li, W., Lvy, L., & Huo, J. (2021) · Research Square · doi:10.21203/rs.3.rs-151398/v1

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Ellsworth, K. A., & Wang, L. (2014)

Hec1/Ndc80 is overexpressed in human gastric cancer and regulates cell growth

Ract, R. T., & Liu, C. (2014)

Systemic effects of mastitis in the dairy cow : identifying mechanisms underlying impaired lactation in non-inflamed glands

Shangraw, E. M. (2020) · doi:10.32469/10355/81499

Clinical Implications in Understanding Prostate Cancer Biology: From Androgen Receptor to Molecular Target Therapy in Metastatic Castration Resistant Prostate Cancer

Ricardo, E. D., Uchiyama, A. A. T., Shimba, D. S., & Kann, A. G. (2021) · Acta Scientific Cancer Biology · doi:10.31080/ascb.2021.04.0308

Comprehensive Analysis of Prognostic and Immune Infiltrates for CBX Family in Human Pancreatic AdenocarcinomaPreprint

Li, Q., Fu, L., wu, D. Y., & wang, F. J. (2021) · Research Square · doi:10.21203/rs.3.rs-580431/v1

Repression of PHLPP by miR-190 Contributes to Arsenic-Induced Akt Activation and Carcinogenesis

Beezhold, K. (2011) · The Research Repository @ WVU (West Virginia University) · doi:10.33915/etd.3421

Overexpressing PLOD Family Genes Predict Poor Prognosis In Pancreatic CancerPreprint

Zhang, J., Tian, Y. Z., Mo, S., & Fu, X. (2021) · Research Square · doi:10.21203/rs.3.rs-895700/v1

Faculty Opinions recommendation of Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation.

Stingl, J. (2012) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.716598070.792003121

FKBP5 Epialleles

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FKBP (FK506 Binding Protein)

D’Arrigo, P., Tufano, M., Rea, A., Romano, S., & Romano, M. F. (2017) · Springer eBooks · doi:10.1007/978-3-319-67199-4_101769

Identification of IFITM1 with prognostic value in pancreatic cancer using network module-based analysisPreprint

Wu, L., Zhu, X., Tang, M., Wang, L., Ma, C., Liang, T., & Yan, S. (2020) · Research Square · doi:10.21203/rs.3.rs-45691/v1

Peer Review #1 of "Identifying disease-associated signaling pathways through a novel effector gene analysis (v0.1)"

(2020) · PeerJ · doi:10.7287/peerj.9695v0.1/reviews/1

Identification and functional characterisation of TGFB: Regulated and cell surface candidates in pancreatic cancer

Monkman, J. H. (2021) · Queensland University of Technology · doi:10.5204/thesis.eprints.213218

Peer Review #1 of "Identifying disease-associated signaling pathways through a novel effector gene analysis (v0.2)"

(2020) · PeerJ · doi:10.7287/peerj.9695v0.2/reviews/1

Functional non-invasive detection of glycolytic pancreatic ductal adenocarcinomaPreprint

Heid, I., Münch, C., Karakaya, S., Lueong, S., Winkelkotte, A. M., Liffers, S. T., Godfrey, L., Cheung, P. F., Savvatakis, K., Topping, G. J., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1753218/v1

FK506 (Tacrolimus) can suppress the progression of colorectal cancer via the FKBP51 - NF-κB signaling pathwayPreprint

Wang, C., Xia, Z., & Cong, J. (2022) · Research Square · doi:10.21203/rs.3.rs-2329149/v1

Efficient Novel Approach Prediction of Survival Time on Pancreatic Cancer Using Machine Learning Paradigms Toward Big Data Analytics

Reddy, P. S., & Sekhar, M. C. (2023) · Advances in intelligent systems and computing · doi:10.1007/978-981-19-5443-6_48

Data from Anti-VEGF Treatment–Resistant Pancreatic Cancers Secrete Proinflammatory Factors That Contribute to Malignant Progression by Inducing an EMT Cell Phenotype

Carbone, C., Moccia, T., Zhu, C., Paradiso, G., Budillon, A., Chiao, P. J., Abbruzzese, J. L., & Melisi, D. (2023) · doi:10.1158/1078-0432.c.6519875.v1

Data from Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer

Fasching, P. A., Liu, D., Scully, S. J., Ingle, J. N., Junior, P. C. M. L., Rack, B. K., Hein, A., Ekici, A. B., Reis, A., Schneeweiß, A., et al. (2023) · doi:10.1158/1078-0432.c.6531272.v1

Data from Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer

Fasching, P. A., Liu, D., Scully, S. J., Ingle, J. N., Junior, P. C. M. L., Rack, B. K., Hein, A., Ekici, A. B., Reis, A., Schneeweiß, A., et al. (2023) · doi:10.1158/1078-0432.c.6531272

Data from Anti-VEGF Treatment–Resistant Pancreatic Cancers Secrete Proinflammatory Factors That Contribute to Malignant Progression by Inducing an EMT Cell Phenotype

Carbone, C., Moccia, T., Zhu, C., Paradiso, G., Budillon, A., Chiao, P. J., Abbruzzese, J. L., & Melisi, D. (2023) · doi:10.1158/1078-0432.c.6519875

Supplementary Tables from Constitutive β-Catenin Activation Induces Male-Specific Tumorigenesis in the Bladder Urothelium

Lin, C., Yin, Y., Stemler, K. M., Humphrey, P. A., Kibel, A. S., Mysorekar, I. U., & Ma, L. (2023) · doi:10.1158/0008-5472.22398033

Supplementary Tables from Constitutive β-Catenin Activation Induces Male-Specific Tumorigenesis in the Bladder Urothelium

Lin, C., Yin, Y., Stemler, K. M., Humphrey, P. A., Kibel, A. S., Mysorekar, I. U., & Ma, L. (2023) · doi:10.1158/0008-5472.22398033.v1

Caspase 8 protects pancreatic neoplasia from KRAS-driven necroptotic primingPreprint

Tishina, S., Dahlhaus, A., Androulidaki, A., Kotliar, M., Mulalic, L., Rakhsh-Khorshid, H., Hocher, F., Stroh, J., Beck, J., Manik, M., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2971504/v1

Relationship Between FKBP5 Polymorphisms at Rs1334894, Rs9394309, and Rs6912833 Loci, and Dyslipidemia in Pediatric Nephrotic Syndrome

Peng, S., Yang, F., Guo, Z., & Liu, D. (2023) · American Journal of Pediatrics · doi:10.11648/j.ajp.20230902.13

Integrated analysis reveals potential significance of FKBP5 in the prognosis and immunity of osteoarthritis and pan-cancer

Xiao, Y., Wang, Y., Xu, X., Jiao, X., & Huo, Y. (2023) · Electronic Journal of Biotechnology · doi:10.1016/j.ejbt.2023.05.002

Oncogenic KRAS-induces necroptotic priming of pancreatic neoplasiaPreprint

Tishina, S., Dahlhaus, A., Androulidaki, A., Kotliar, M., Mulalic, L., Rakhsh-Khorshid, H., Hocher, F., Stroh, J., Beck, J., Manik, M., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2971504/v2

Additional file 3 of Identification and functional analysis of novel oncogene DDX60L in pancreatic ductal adenocarcinoma

Wu, H., Tian, W., Tai, X., Li, X., Li, Z., Shui, J., Yu, J., Wang, Z., & Zhu, X. (2021) · Figshare · doi:10.6084/m9.figshare.17037432

Additional file 3 of Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma

Heid, I., Münch, C., Karakaya, S., Lueong, S., Winkelkotte, A. M., Liffers, S. T., Godfrey, L., Cheung, P. F., Savvatakis, K., Topping, G. J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22601486

Additional file 5 of Identification and functional analysis of novel oncogene DDX60L in pancreatic ductal adenocarcinoma

Wu, H., Tian, W., Tai, X., Li, X., Li, Z., Shui, J., Yu, J., Wang, Z., & Zhu, X. (2021) · Figshare · doi:10.6084/m9.figshare.17037447

Additional file 5 of Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma

Heid, I., Münch, C., Karakaya, S., Lueong, S., Winkelkotte, A. M., Liffers, S. T., Godfrey, L., Cheung, P. F., Savvatakis, K., Topping, G. J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22601492

Additional file 6 of Identification and functional analysis of novel oncogene DDX60L in pancreatic ductal adenocarcinoma

Wu, H., Tian, W., Tai, X., Li, X., Li, Z., Shui, J., Yu, J., Wang, Z., & Zhu, X. (2021) · Figshare · doi:10.6084/m9.figshare.17037453

Additional file 7 of Identification and functional analysis of novel oncogene DDX60L in pancreatic ductal adenocarcinoma

Wu, H., Tian, W., Tai, X., Li, X., Li, Z., Shui, J., Yu, J., Wang, Z., & Zhu, X. (2021) · Figshare · doi:10.6084/m9.figshare.17037459

Additional file 4 of Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma

Heid, I., Münch, C., Karakaya, S., Lueong, S., Winkelkotte, A. M., Liffers, S. T., Godfrey, L., Cheung, P. F., Savvatakis, K., Topping, G. J., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22601489

Additional file 4 of Identification and functional analysis of novel oncogene DDX60L in pancreatic ductal adenocarcinoma

Wu, H., Tian, W., Tai, X., Li, X., Li, Z., Shui, J., Yu, J., Wang, Z., & Zhu, X. (2021) · Figshare · doi:10.6084/m9.figshare.17037438

Deeply Saddening Life Events Play a Carcinogenic Role by Inducing Mutations in ALOX12 and FKBP5 Genes

Kutluhan, A., Topak, O. Z., Akça, H., Tokgün, P. E., Özdel, O. İ., Yılmaz, S., Sungurtekin, U., Erdem, E., & Yaren, A. (2024) · Genes · doi:10.3390/genes15121531

Deciphering the potential ability of DExD/H-box helicase 60 (DDX60) on the proliferation, diagnostic and prognostic biomarker in pancreatic cancer: a research based on silico, RNA-seq and molecular biology experiment

Zhang, D., Zhang, E., Cai, Y., sun, Y., Zeng, P., Jiang, X., & Lian, Y. (2025) · Hereditas · doi:10.1186/s41065-024-00361-9

The downregulation of FKBP5 contributes to the pathogenesis of adenomyosis and is associated with impaired endometrial receptivity

Wang, M., Xiang, Y., Zhang, D., Geng, X., Han, X., Guo, P., Zhang, L., & Tan, L. (2025) · Biology of Reproduction · doi:10.1093/biolre/ioaf126

From Metabolism to Malignancy: Profiling Diabetes-Related Genes in Hepatocellular CarcinomaPreprint

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